ProfileGDS5420 / 227055_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 8% 7% 24% 9% 3% 9% 2% 29% 15% 2% 14% 6% 9% 1% 12% 3% 6% 31% 22% 26% 8% 20% 18% 23% 18% 27% 3% 6% 14% 35% 7% 28% 7% 9% 46% 1% 32% 4% 5% 25% 2% 36% 14% 21% 42% 11% 12% 12% 9% 2% 12% 9% 3% 14% 20% 42% 7% 33% 20% 14% 26% 5% 34% 36% 22% 36% 33% 10% 11% 1% 1% 41% 14% 62% 64% 8% 0% 12% 24% 33% 10% 60% 6% 40% 31% 16% 29% 53% 70% 2% 10% 8% 50% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose7.858
GSM1296119B_lesional_pre-dose7.917
GSM1296076C_lesional_pre-dose
GSM1296092D_lesional_pre-dose26.3124
GSM1296103E_lesional_pre-dose8.249
GSM1296078F_lesional_pre-dose3.533
GSM1296107G_lesional_pre-dose10.499
GSM1296109H_lesional_pre-dose2.222
GSM1296080I_lesional_pre-dose
GSM1296090J_lesional_pre-dose39.7329
GSM1296074K_lesional_pre-dose14.5215
GSM1296111L_lesional_pre-dose2.92
GSM1296099M_lesional_pre-dose14.1914
GSM1296086O_lesional_pre-dose5.466
GSM1296117P_lesional_pre-dose11.39
GSM1296113Q_lesional_pre-dose2.171
GSM1296096R_lesional_pre-dose10.3312
GSM1296105S_lesional_pre-dose3.53
GSM1296098T_lesional_pre-dose8.416
GSM1296101U_lesional_pre-dose50.5231
GSM1296121V_lesional_pre-dose30.8222
GSM1296088W_lesional_pre-dose
GSM1296082X_lesional_pre-dose32.3526
GSM1296115Y_lesional_pre-dose9.298
GSM1296084Z_lesional_pre-dose25.5320
GSM1296072B_lesional_day823.6818
GSM1296069L_lesional_day839.1723
GSM1296071P_lesional_day826.718
GSM1296070Y_lesional_day8
GSM1296073V_lesional_day844.1827
GSM1296034A_lesional_day153.333
GSM1296041G_lesional_day156.56
GSM1296035R_lesional_day1511.4114
GSM1296038U_lesional_day1565.9235
GSM1296047B_lesional_day159.147
GSM1296039E_lesional_day1543.2728
GSM1296042H_lesional_day158.977
GSM1296043L_lesional_day1511.69
GSM1296037M_lesional_day15140.2246
GSM1296046P_lesional_day152.041
GSM1296044Q_lesional_day1566.1132
GSM1296045Y_lesional_day155.754
GSM1296025C_lesional_day155.365
GSM1296033D_lesional_day1531.725
GSM1296027I_lesional_day151.92
GSM1296032J_lesional_day1571.5236
GSM1296024K_lesional_day1513.9114
GSM1296031W_lesional_day1526.3621
GSM1296028X_lesional_day15103.342
GSM1296029Z_lesional_day1510.7811
GSM1296026F_lesional_day1514.112
GSM1296030O_lesional_day1510.1312
GSM1296040S_lesional_day1510.199
GSM1296036T_lesional_day152.022
GSM1296048V_lesional_day1514.2212
GSM1296059A_lesional_day437.769
GSM1296066G_lesional_day434.043
GSM1296060R_lesional_day4313.2814
GSM1296063U_lesional_day4323.720
GSM1296064E_lesional_day43100.0842
GSM1296067H_lesional_day438.557
GSM1296062M_lesional_day4356.233
GSM1296068Q_lesional_day4333.9920
GSM1296050C_lesional_day4316.6314
GSM1296057D_lesional_day4332.1726
GSM1296052I_lesional_day434.275
GSM1296054J_lesional_day4365.6634
GSM1296049K_lesional_day4368.0436
GSM1296055W_lesional_day4328.0622
GSM1296053X_lesional_day4368.8436
GSM1296058Z_lesional_day4351.0633
GSM1296051F_lesional_day4310.9710
GSM1296056O_lesional_day43
GSM1296065S_lesional_day4310.5211
GSM1296061T_lesional_day431.561
GSM1296095A_non-lesional_pre-dose0.941
GSM1296120B_non-lesional_pre-dose110.5341
GSM1296077C_non-lesional_pre-dose14.2714
GSM1296093D_non-lesional_pre-dose376.0562
GSM1296104E_non-lesional_pre-dose397.7864
GSM1296079F_non-lesional_pre-dose
GSM1296108G_non-lesional_pre-dose9.378
GSM1296110H_non-lesional_pre-dose0.410
GSM1296081I_non-lesional_pre-dose10.5412
GSM1296091J_non-lesional_pre-dose28.6624
GSM1296075K_non-lesional_pre-dose56.4133
GSM1296112L_non-lesional_pre-dose14.6710
GSM1296100M_non-lesional_pre-dose330.660
GSM1296087O_non-lesional_pre-dose5.46
GSM1296118P_non-lesional_pre-dose113.8440
GSM1296114Q_non-lesional_pre-dose62.431
GSM1296097R_non-lesional_pre-dose16.0216
GSM1296106S_non-lesional_pre-dose46.7629
GSM1296102U_non-lesional_pre-dose223.8953
GSM1296122V_non-lesional_pre-dose573.5370
GSM1296089W_non-lesional_pre-dose1.962
GSM1296083X_non-lesional_pre-dose9.8810
GSM1296116Y_non-lesional_pre-dose11.678
GSM1296085Z_non-lesional_pre-dose168.9950