ProfileGDS5420 / 227039_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 54% 50% 48% 45% 52% 59% 67% 39% 43% 42% 61% 50% 50% 56% 65% 47% 50% 48% 58% 57% 44% 48% 59% 42% 52% 65% 64% 62% 52% 53% 60% 50% 50% 55% 42% 61% 64% 55% 65% 63% 61% 39% 38% 40% 38% 40% 40% 34% 41% 49% 44% 52% 45% 57% 50% 61% 53% 50% 41% 60% 49% 61% 39% 36% 41% 46% 40% 42% 39% 45% 40% 43% 47% 50% 50% 56% 42% 39% 38% 39% 61% 65% 25% 49% 43% 68% 46% 36% 64% 66% 51% 47% 47% 54% 39% 41% 62% 35% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose186.9651
GSM1296119B_lesional_pre-dose225.7854
GSM1296076C_lesional_pre-dose157.8350
GSM1296092D_lesional_pre-dose131.9648
GSM1296103E_lesional_pre-dose123.0945
GSM1296078F_lesional_pre-dose172.2552
GSM1296107G_lesional_pre-dose299.559
GSM1296109H_lesional_pre-dose481.4567
GSM1296080I_lesional_pre-dose77.3939
GSM1296090J_lesional_pre-dose104.1843
GSM1296074K_lesional_pre-dose89.6842
GSM1296111L_lesional_pre-dose332.761
GSM1296099M_lesional_pre-dose171.6750
GSM1296086O_lesional_pre-dose155.4750
GSM1296117P_lesional_pre-dose268.2156
GSM1296113Q_lesional_pre-dose432.8365
GSM1296096R_lesional_pre-dose138.0147
GSM1296105S_lesional_pre-dose182.4450
GSM1296098T_lesional_pre-dose153.7948
GSM1296101U_lesional_pre-dose296.8258
GSM1296121V_lesional_pre-dose260.5257
GSM1296088W_lesional_pre-dose109.6144
GSM1296082X_lesional_pre-dose135.0548
GSM1296115Y_lesional_pre-dose308.5359
GSM1296084Z_lesional_pre-dose103.9142
GSM1296072B_lesional_day8212.0252
GSM1296069L_lesional_day8435.3565
GSM1296071P_lesional_day8419.3764
GSM1296070Y_lesional_day8373.4862
GSM1296073V_lesional_day8192.6652
GSM1296034A_lesional_day15229.7753
GSM1296041G_lesional_day15318.7860
GSM1296035R_lesional_day15170.9950
GSM1296038U_lesional_day15174.4550
GSM1296047B_lesional_day15248.3355
GSM1296039E_lesional_day15102.9642
GSM1296042H_lesional_day15338.161
GSM1296043L_lesional_day15421.0264
GSM1296037M_lesional_day15245.855
GSM1296046P_lesional_day15444.3565
GSM1296044Q_lesional_day15396.5263
GSM1296045Y_lesional_day15354.661
GSM1296025C_lesional_day1581.8139
GSM1296033D_lesional_day1579.7738
GSM1296027I_lesional_day1580.3940
GSM1296032J_lesional_day1580.8838
GSM1296024K_lesional_day1586.4440
GSM1296031W_lesional_day1597.4440
GSM1296028X_lesional_day1559.7234
GSM1296029Z_lesional_day1598.8541
GSM1296026F_lesional_day15153.8349
GSM1296030O_lesional_day15100.3844
GSM1296040S_lesional_day15196.2952
GSM1296036T_lesional_day15139.4145
GSM1296048V_lesional_day15264.4557
GSM1296059A_lesional_day43163.5450
GSM1296066G_lesional_day43350.3661
GSM1296060R_lesional_day43208.5153
GSM1296063U_lesional_day43179.0550
GSM1296064E_lesional_day4391.6941
GSM1296067H_lesional_day43341.7360
GSM1296062M_lesional_day43162.6349
GSM1296068Q_lesional_day43362.4361
GSM1296050C_lesional_day4386.9539
GSM1296057D_lesional_day4369.536
GSM1296052I_lesional_day4387.5341
GSM1296054J_lesional_day43143.7446
GSM1296049K_lesional_day4390.2740
GSM1296055W_lesional_day43109.8642
GSM1296053X_lesional_day4384.8539
GSM1296058Z_lesional_day43120.6545
GSM1296051F_lesional_day4388.4940
GSM1296056O_lesional_day43100.2543
GSM1296065S_lesional_day43144.6847
GSM1296061T_lesional_day43173.4450
GSM1296095A_non-lesional_pre-dose171.4450
GSM1296120B_non-lesional_pre-dose259.7456
GSM1296077C_non-lesional_pre-dose100.242
GSM1296093D_non-lesional_pre-dose90.5939
GSM1296104E_non-lesional_pre-dose78.8638
GSM1296079F_non-lesional_pre-dose81.4339
GSM1296108G_non-lesional_pre-dose352.7361
GSM1296110H_non-lesional_pre-dose444.8965
GSM1296081I_non-lesional_pre-dose29.3425
GSM1296091J_non-lesional_pre-dose150.2249
GSM1296075K_non-lesional_pre-dose101.7343
GSM1296112L_non-lesional_pre-dose532.5868
GSM1296100M_non-lesional_pre-dose140.1646
GSM1296087O_non-lesional_pre-dose59.2936
GSM1296118P_non-lesional_pre-dose428.0664
GSM1296114Q_non-lesional_pre-dose464.5466
GSM1296097R_non-lesional_pre-dose180.3351
GSM1296106S_non-lesional_pre-dose155.3547
GSM1296102U_non-lesional_pre-dose158.4247
GSM1296122V_non-lesional_pre-dose236.1954
GSM1296089W_non-lesional_pre-dose92.5239
GSM1296083X_non-lesional_pre-dose98.9441
GSM1296116Y_non-lesional_pre-dose385.7162
GSM1296085Z_non-lesional_pre-dose65.2835