ProfileGDS5420 / 226754_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 61% 55% 50% 61% 54% 56% 57% 75% 56% 59% 53% 65% 55% 55% 53% 66% 71% 72% 65% 62% 61% 45% 55% 65% 64% 60% 68% 60% 52% 84% 56% 66% 59% 66% 59% 60% 62% 71% 66% 61% 60% 81% 67% 70% 73% 83% 65% 67% 72% 72% 67% 68% 73% 63% 66% 59% 69% 59% 59% 73% 72% 62% 69% 68% 69% 74% 81% 63% 70% 69% 65% 61% 66% 79% 65% 65% 75% 78% 57% 75% 58% 66% 75% 58% 67% 63% 74% 64% 67% 56% 72% 69% 73% 75% 61% 80% 62% 72% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose578.4770
GSM1296119B_lesional_pre-dose344.4861
GSM1296076C_lesional_pre-dose207.5255
GSM1296092D_lesional_pre-dose151.6650
GSM1296103E_lesional_pre-dose341.9461
GSM1296078F_lesional_pre-dose193.954
GSM1296107G_lesional_pre-dose256.4456
GSM1296109H_lesional_pre-dose280.3257
GSM1296080I_lesional_pre-dose809.0575
GSM1296090J_lesional_pre-dose229.9656
GSM1296074K_lesional_pre-dose272.3259
GSM1296111L_lesional_pre-dose218.753
GSM1296099M_lesional_pre-dose431.4765
GSM1296086O_lesional_pre-dose214.6655
GSM1296117P_lesional_pre-dose250.0355
GSM1296113Q_lesional_pre-dose234.853
GSM1296096R_lesional_pre-dose451.6466
GSM1296105S_lesional_pre-dose616.7871
GSM1296098T_lesional_pre-dose652.7672
GSM1296101U_lesional_pre-dose450.2665
GSM1296121V_lesional_pre-dose362.4262
GSM1296088W_lesional_pre-dose323.3961
GSM1296082X_lesional_pre-dose109.8545
GSM1296115Y_lesional_pre-dose241.1455
GSM1296084Z_lesional_pre-dose416.2365
GSM1296072B_lesional_day8402.4964
GSM1296069L_lesional_day8328.3260
GSM1296071P_lesional_day8527.8168
GSM1296070Y_lesional_day8342.8960
GSM1296073V_lesional_day8191.2952
GSM1296034A_lesional_day151293.5984
GSM1296041G_lesional_day15247.7156
GSM1296035R_lesional_day15463.666
GSM1296038U_lesional_day15307.9659
GSM1296047B_lesional_day15469.8266
GSM1296039E_lesional_day15294.6959
GSM1296042H_lesional_day15332.4760
GSM1296043L_lesional_day15369.6262
GSM1296037M_lesional_day15600.7771
GSM1296046P_lesional_day15472.8666
GSM1296044Q_lesional_day15349.8661
GSM1296045Y_lesional_day15330.2360
GSM1296025C_lesional_day151178.8381
GSM1296033D_lesional_day15487.4867
GSM1296027I_lesional_day15583.9470
GSM1296032J_lesional_day15693.2873
GSM1296024K_lesional_day151337.9983
GSM1296031W_lesional_day15443.1165
GSM1296028X_lesional_day15488.4567
GSM1296029Z_lesional_day15659.0572
GSM1296026F_lesional_day15637.9472
GSM1296030O_lesional_day15477.7167
GSM1296040S_lesional_day15512.1668
GSM1296036T_lesional_day15686.6473
GSM1296048V_lesional_day15375.5863
GSM1296059A_lesional_day4345366
GSM1296066G_lesional_day43305.2159
GSM1296060R_lesional_day43558.4469
GSM1296063U_lesional_day43305.7759
GSM1296064E_lesional_day43281.9959
GSM1296067H_lesional_day43684.373
GSM1296062M_lesional_day43671.3772
GSM1296068Q_lesional_day43388.6662
GSM1296050C_lesional_day43542.3769
GSM1296057D_lesional_day43522.4368
GSM1296052I_lesional_day43521.4969
GSM1296054J_lesional_day43737.1374
GSM1296049K_lesional_day431172.3181
GSM1296055W_lesional_day43392.0663
GSM1296053X_lesional_day43596.5870
GSM1296058Z_lesional_day43558.8269
GSM1296051F_lesional_day43397.0665
GSM1296056O_lesional_day43325.7461
GSM1296065S_lesional_day43450.6766
GSM1296061T_lesional_day431010.579
GSM1296095A_non-lesional_pre-dose418.7265
GSM1296120B_non-lesional_pre-dose424.2465
GSM1296077C_non-lesional_pre-dose774.2375
GSM1296093D_non-lesional_pre-dose926.278
GSM1296104E_non-lesional_pre-dose260.4257
GSM1296079F_non-lesional_pre-dose782.275
GSM1296108G_non-lesional_pre-dose296.3358
GSM1296110H_non-lesional_pre-dose462.2966
GSM1296081I_non-lesional_pre-dose767.3775
GSM1296091J_non-lesional_pre-dose277.5458
GSM1296075K_non-lesional_pre-dose445.0967
GSM1296112L_non-lesional_pre-dose394.6863
GSM1296100M_non-lesional_pre-dose739.7274
GSM1296087O_non-lesional_pre-dose381.2864
GSM1296118P_non-lesional_pre-dose495.5567
GSM1296114Q_non-lesional_pre-dose273.2156
GSM1296097R_non-lesional_pre-dose634.4372
GSM1296106S_non-lesional_pre-dose559.7369
GSM1296102U_non-lesional_pre-dose691.973
GSM1296122V_non-lesional_pre-dose749.175
GSM1296089W_non-lesional_pre-dose358.6461
GSM1296083X_non-lesional_pre-dose1045.2380
GSM1296116Y_non-lesional_pre-dose372.7262
GSM1296085Z_non-lesional_pre-dose647.9972