ProfileGDS5420 / 226267_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 65% 66% 63% 64% 66% 66% 63% 59% 66% 63% 65% 67% 63% 66% 64% 64% 67% 61% 68% 71% 65% 67% 64% 64% 70% 65% 69% 67% 66% 64% 69% 60% 69% 70% 66% 66% 66% 70% 66% 65% 65% 68% 65% 64% 69% 63% 66% 71% 65% 66% 69% 67% 66% 65% 71% 68% 62% 65% 68% 66% 66% 64% 65% 65% 69% 69% 66% 67% 78% 67% 74% 69% 69% 66% 67% 71% 68% 68% 58% 65% 63% 69% 67% 70% 67% 68% 67% 64% 72% 66% 62% 70% 66% 71% 65% 74% 73% 67% 61% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose441.965
GSM1296119B_lesional_pre-dose459.266
GSM1296076C_lesional_pre-dose349.8863
GSM1296092D_lesional_pre-dose388.1364
GSM1296103E_lesional_pre-dose454.4866
GSM1296078F_lesional_pre-dose427.5266
GSM1296107G_lesional_pre-dose388.6163
GSM1296109H_lesional_pre-dose311.2659
GSM1296080I_lesional_pre-dose432.666
GSM1296090J_lesional_pre-dose362.763
GSM1296074K_lesional_pre-dose388.3265
GSM1296111L_lesional_pre-dose474.9967
GSM1296099M_lesional_pre-dose380.8163
GSM1296086O_lesional_pre-dose432.9766
GSM1296117P_lesional_pre-dose404.7264
GSM1296113Q_lesional_pre-dose414.0264
GSM1296096R_lesional_pre-dose471.1267
GSM1296105S_lesional_pre-dose353.2461
GSM1296098T_lesional_pre-dose524.3168
GSM1296101U_lesional_pre-dose629.771
GSM1296121V_lesional_pre-dose418.2265
GSM1296088W_lesional_pre-dose48767
GSM1296082X_lesional_pre-dose369.0964
GSM1296115Y_lesional_pre-dose394.6964
GSM1296084Z_lesional_pre-dose579.1470
GSM1296072B_lesional_day8424.2765
GSM1296069L_lesional_day8562.9469
GSM1296071P_lesional_day8487.6367
GSM1296070Y_lesional_day8454.1766
GSM1296073V_lesional_day8385.3464
GSM1296034A_lesional_day15574.3969
GSM1296041G_lesional_day15324.5560
GSM1296035R_lesional_day15546.2569
GSM1296038U_lesional_day15588.2770
GSM1296047B_lesional_day15454.0466
GSM1296039E_lesional_day15431.7966
GSM1296042H_lesional_day15447.2966
GSM1296043L_lesional_day15573.9170
GSM1296037M_lesional_day15461.0166
GSM1296046P_lesional_day15435.6965
GSM1296044Q_lesional_day15447.765
GSM1296045Y_lesional_day15527.4368
GSM1296025C_lesional_day15415.9265
GSM1296033D_lesional_day15407.5964
GSM1296027I_lesional_day15544.9569
GSM1296032J_lesional_day15384.8263
GSM1296024K_lesional_day15455.866
GSM1296031W_lesional_day15608.6571
GSM1296028X_lesional_day15427.1565
GSM1296029Z_lesional_day15448.9266
GSM1296026F_lesional_day15533.9469
GSM1296030O_lesional_day15472.7667
GSM1296040S_lesional_day15470.7166
GSM1296036T_lesional_day15457.0965
GSM1296048V_lesional_day15589.771
GSM1296059A_lesional_day43529.0868
GSM1296066G_lesional_day43363.5262
GSM1296060R_lesional_day43437.7365
GSM1296063U_lesional_day43507.2768
GSM1296064E_lesional_day43432.9766
GSM1296067H_lesional_day43462.5766
GSM1296062M_lesional_day43426.9164
GSM1296068Q_lesional_day43453.0465
GSM1296050C_lesional_day43406.0365
GSM1296057D_lesional_day43564.7969
GSM1296052I_lesional_day43541.0569
GSM1296054J_lesional_day43458.3566
GSM1296049K_lesional_day43481.5667
GSM1296055W_lesional_day43936.1678
GSM1296053X_lesional_day43488.6367
GSM1296058Z_lesional_day43755.774
GSM1296051F_lesional_day43509.2269
GSM1296056O_lesional_day43542.1669
GSM1296065S_lesional_day43454.7366
GSM1296061T_lesional_day43493.4567
GSM1296095A_non-lesional_pre-dose605.2271
GSM1296120B_non-lesional_pre-dose501.5468
GSM1296077C_non-lesional_pre-dose488.6868
GSM1296093D_non-lesional_pre-dose292.6358
GSM1296104E_non-lesional_pre-dose417.8565
GSM1296079F_non-lesional_pre-dose365.6163
GSM1296108G_non-lesional_pre-dose555.6469
GSM1296110H_non-lesional_pre-dose492.4967
GSM1296081I_non-lesional_pre-dose573.4570
GSM1296091J_non-lesional_pre-dose480.6367
GSM1296075K_non-lesional_pre-dose499.1568
GSM1296112L_non-lesional_pre-dose491.767
GSM1296100M_non-lesional_pre-dose412.4464
GSM1296087O_non-lesional_pre-dose642.8272
GSM1296118P_non-lesional_pre-dose471.0566
GSM1296114Q_non-lesional_pre-dose376.0862
GSM1296097R_non-lesional_pre-dose583.0670
GSM1296106S_non-lesional_pre-dose454.0766
GSM1296102U_non-lesional_pre-dose624.8571
GSM1296122V_non-lesional_pre-dose422.2965
GSM1296089W_non-lesional_pre-dose745.0474
GSM1296083X_non-lesional_pre-dose712.6173
GSM1296116Y_non-lesional_pre-dose503.0567
GSM1296085Z_non-lesional_pre-dose336.5361