ProfileGDS5420 / 226088_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 81% 63% 61% 71% 78% 62% 71% 75% 73% 66% 62% 59% 74% 66% 71% 65% 76% 66% 78% 78% 65% 75% 69% 68% 70% 60% 51% 64% 57% 60% 64% 62% 77% 74% 55% 71% 63% 65% 66% 51% 59% 62% 46% 72% 62% 58% 52% 60% 64% 64% 62% 70% 77% 72% 65% 75% 62% 74% 63% 63% 56% 73% 49% 44% 66% 62% 57% 49% 65% 62% 67% 57% 71% 67% 72% 71% 63% 56% 63% 57% 54% 62% 56% 50% 68% 53% 56% 65% 65% 49% 52% 69% 63% 65% 53% 59% 63% 54% 62% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1146.0281
GSM1296119B_lesional_pre-dose371.5163
GSM1296076C_lesional_pre-dose310.7561
GSM1296092D_lesional_pre-dose621.3671
GSM1296103E_lesional_pre-dose962.4578
GSM1296078F_lesional_pre-dose327.3762
GSM1296107G_lesional_pre-dose588.4171
GSM1296109H_lesional_pre-dose754.8975
GSM1296080I_lesional_pre-dose692.3973
GSM1296090J_lesional_pre-dose447.0766
GSM1296074K_lesional_pre-dose319.4762
GSM1296111L_lesional_pre-dose307.3759
GSM1296099M_lesional_pre-dose756.2874
GSM1296086O_lesional_pre-dose441.6866
GSM1296117P_lesional_pre-dose596.5371
GSM1296113Q_lesional_pre-dose431.3365
GSM1296096R_lesional_pre-dose813.176
GSM1296105S_lesional_pre-dose457.1666
GSM1296098T_lesional_pre-dose945.1778
GSM1296101U_lesional_pre-dose932.778
GSM1296121V_lesional_pre-dose422.5865
GSM1296088W_lesional_pre-dose800.8475
GSM1296082X_lesional_pre-dose521.9769
GSM1296115Y_lesional_pre-dose519.5168
GSM1296084Z_lesional_pre-dose558.7870
GSM1296072B_lesional_day8319.960
GSM1296069L_lesional_day8204.8351
GSM1296071P_lesional_day8411.2464
GSM1296070Y_lesional_day8289.1657
GSM1296073V_lesional_day8307.860
GSM1296034A_lesional_day15430.6664
GSM1296041G_lesional_day15350.9962
GSM1296035R_lesional_day15909.6277
GSM1296038U_lesional_day15742.5874
GSM1296047B_lesional_day15242.2555
GSM1296039E_lesional_day15587.4971
GSM1296042H_lesional_day15381.9563
GSM1296043L_lesional_day15439.8465
GSM1296037M_lesional_day15468.7266
GSM1296046P_lesional_day15206.2351
GSM1296044Q_lesional_day15317.5759
GSM1296045Y_lesional_day15370.3862
GSM1296025C_lesional_day15133.7146
GSM1296033D_lesional_day15652.2372
GSM1296027I_lesional_day15337.5662
GSM1296032J_lesional_day15290.3858
GSM1296024K_lesional_day15181.7552
GSM1296031W_lesional_day15338.9760
GSM1296028X_lesional_day15398.6764
GSM1296029Z_lesional_day15404.464
GSM1296026F_lesional_day15349.0262
GSM1296030O_lesional_day15573.9570
GSM1296040S_lesional_day15871.5677
GSM1296036T_lesional_day15680.6372
GSM1296048V_lesional_day15428.5865
GSM1296059A_lesional_day43805.7175
GSM1296066G_lesional_day43374.1762
GSM1296060R_lesional_day43748.4974
GSM1296063U_lesional_day43370.9963
GSM1296064E_lesional_day43357.2663
GSM1296067H_lesional_day43273.6356
GSM1296062M_lesional_day43716.5273
GSM1296068Q_lesional_day43193.8749
GSM1296050C_lesional_day43121.8644
GSM1296057D_lesional_day43467.0966
GSM1296052I_lesional_day43336.8862
GSM1296054J_lesional_day43282.2257
GSM1296049K_lesional_day43157.5249
GSM1296055W_lesional_day43427.7565
GSM1296053X_lesional_day43367.1562
GSM1296058Z_lesional_day43482.5267
GSM1296051F_lesional_day43242.4957
GSM1296056O_lesional_day43589.8271
GSM1296065S_lesional_day43493.5867
GSM1296061T_lesional_day43677.2472
GSM1296095A_non-lesional_pre-dose600.0671
GSM1296120B_non-lesional_pre-dose380.9663
GSM1296077C_non-lesional_pre-dose245.7456
GSM1296093D_non-lesional_pre-dose392.0963
GSM1296104E_non-lesional_pre-dose259.6957
GSM1296079F_non-lesional_pre-dose207.454
GSM1296108G_non-lesional_pre-dose362.8362
GSM1296110H_non-lesional_pre-dose272.8456
GSM1296081I_non-lesional_pre-dose157.4350
GSM1296091J_non-lesional_pre-dose495.1968
GSM1296075K_non-lesional_pre-dose192.253
GSM1296112L_non-lesional_pre-dose274.1256
GSM1296100M_non-lesional_pre-dose432.6465
GSM1296087O_non-lesional_pre-dose399.9165
GSM1296118P_non-lesional_pre-dose179.8749
GSM1296114Q_non-lesional_pre-dose214.5252
GSM1296097R_non-lesional_pre-dose532.5469
GSM1296106S_non-lesional_pre-dose394.6663
GSM1296102U_non-lesional_pre-dose461.7565
GSM1296122V_non-lesional_pre-dose224.453
GSM1296089W_non-lesional_pre-dose317.2859
GSM1296083X_non-lesional_pre-dose377.9763
GSM1296116Y_non-lesional_pre-dose246.8554
GSM1296085Z_non-lesional_pre-dose353.862