ProfileGDS5420 / 225446_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 77% 82% 74% 59% 85% 79% 63% 51% 76% 80% 81% 69% 71% 80% 80% 69% 64% 51% 57% 75% 68% 76% 81% 62% 75% 79% 78% 83% 80% 41% 85% 68% 69% 74% 71% 80% 79% 66% 83% 80% 81% 67% 69% 64% 69% 61% 65% 67% 62% 68% 64% 55% 53% 78% 59% 84% 68% 76% 76% 72% 60% 82% 79% 67% 61% 61% 68% 68% 56% 63% 77% 68% 73% 55% 70% 77% 71% 57% 74% 69% 80% 74% 58% 77% 79% 78% 68% 69% 82% 82% 73% 67% 61% 75% 67% 63% 82% 66% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose241.6155
GSM1296119B_lesional_pre-dose84277
GSM1296076C_lesional_pre-dose1210.782
GSM1296092D_lesional_pre-dose714.7374
GSM1296103E_lesional_pre-dose293.7459
GSM1296078F_lesional_pre-dose1508.4485
GSM1296107G_lesional_pre-dose958.7479
GSM1296109H_lesional_pre-dose396.663
GSM1296080I_lesional_pre-dose175.3451
GSM1296090J_lesional_pre-dose810.5876
GSM1296074K_lesional_pre-dose1125.9480
GSM1296111L_lesional_pre-dose1079.1281
GSM1296099M_lesional_pre-dose547.1969
GSM1296086O_lesional_pre-dose585.7271
GSM1296117P_lesional_pre-dose1047.5180
GSM1296113Q_lesional_pre-dose1027.7680
GSM1296096R_lesional_pre-dose534.8269
GSM1296105S_lesional_pre-dose424.0264
GSM1296098T_lesional_pre-dose185.5151
GSM1296101U_lesional_pre-dose275.6157
GSM1296121V_lesional_pre-dose769.9275
GSM1296088W_lesional_pre-dose503.2568
GSM1296082X_lesional_pre-dose807.0176
GSM1296115Y_lesional_pre-dose1144.581
GSM1296084Z_lesional_pre-dose359.7762
GSM1296072B_lesional_day8753.9775
GSM1296069L_lesional_day8987.5279
GSM1296071P_lesional_day8897.778
GSM1296070Y_lesional_day81247.5383
GSM1296073V_lesional_day81036.0580
GSM1296034A_lesional_day15102.9241
GSM1296041G_lesional_day151472.5985
GSM1296035R_lesional_day15531.0368
GSM1296038U_lesional_day15554.7469
GSM1296047B_lesional_day15749.9874
GSM1296039E_lesional_day15610.9171
GSM1296042H_lesional_day151052.280
GSM1296043L_lesional_day15995.2579
GSM1296037M_lesional_day15452.7666
GSM1296046P_lesional_day151243.5583
GSM1296044Q_lesional_day151020.0780
GSM1296045Y_lesional_day151116.0581
GSM1296025C_lesional_day15464.8467
GSM1296033D_lesional_day15545.5769
GSM1296027I_lesional_day15380.5864
GSM1296032J_lesional_day15540.8369
GSM1296024K_lesional_day15321.8161
GSM1296031W_lesional_day15434.1465
GSM1296028X_lesional_day15472.5967
GSM1296029Z_lesional_day15369.8262
GSM1296026F_lesional_day15491.568
GSM1296030O_lesional_day15394.8364
GSM1296040S_lesional_day15234.555
GSM1296036T_lesional_day15225.8353
GSM1296048V_lesional_day15918.8978
GSM1296059A_lesional_day43294.859
GSM1296066G_lesional_day431356.3984
GSM1296060R_lesional_day43517.3368
GSM1296063U_lesional_day43825.5376
GSM1296064E_lesional_day43796.3976
GSM1296067H_lesional_day43656.7372
GSM1296062M_lesional_day43321.9560
GSM1296068Q_lesional_day431183.4682
GSM1296050C_lesional_day43975.3879
GSM1296057D_lesional_day43502.4767
GSM1296052I_lesional_day43320.0661
GSM1296054J_lesional_day43356.3661
GSM1296049K_lesional_day43505.6168
GSM1296055W_lesional_day43524.7468
GSM1296053X_lesional_day43260.2656
GSM1296058Z_lesional_day43390.4363
GSM1296051F_lesional_day43892.3277
GSM1296056O_lesional_day43493.6768
GSM1296065S_lesional_day43704.7573
GSM1296061T_lesional_day43244.6655
GSM1296095A_non-lesional_pre-dose563.6470
GSM1296120B_non-lesional_pre-dose884.4577
GSM1296077C_non-lesional_pre-dose600.3671
GSM1296093D_non-lesional_pre-dose283.0457
GSM1296104E_non-lesional_pre-dose702.5474
GSM1296079F_non-lesional_pre-dose536.2669
GSM1296108G_non-lesional_pre-dose1033.2780
GSM1296110H_non-lesional_pre-dose744.0674
GSM1296081I_non-lesional_pre-dose273.1558
GSM1296091J_non-lesional_pre-dose894.7477
GSM1296075K_non-lesional_pre-dose1020.2379
GSM1296112L_non-lesional_pre-dose933.8178
GSM1296100M_non-lesional_pre-dose514.5568
GSM1296087O_non-lesional_pre-dose531.9869
GSM1296118P_non-lesional_pre-dose1123.4782
GSM1296114Q_non-lesional_pre-dose1185.3282
GSM1296097R_non-lesional_pre-dose691.8473
GSM1296106S_non-lesional_pre-dose495.1467
GSM1296102U_non-lesional_pre-dose358.2161
GSM1296122V_non-lesional_pre-dose784.3875
GSM1296089W_non-lesional_pre-dose486.7867
GSM1296083X_non-lesional_pre-dose385.7663
GSM1296116Y_non-lesional_pre-dose1123.1182
GSM1296085Z_non-lesional_pre-dose446.1766