ProfileGDS5420 / 225424_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 64% 64% 67% 62% 81% 92% 64% 61% 66% 68% 76% 60% 72% 61% 58% 62% 91% 55% 60% 67% 63% 57% 70% 58% 68% 85% 75% 79% 73% 60% 88% 59% 78% 63% 59% 81% 79% 64% 69% 95% 84% 91% 72% 81% 95% 89% 94% 64% 71% 75% 73% 83% 58% 72% 60% 86% 70% 91% 70% 82% 60% 99% 98% 87% 86% 66% 89% 87% 66% 68% 82% 70% 99% 84% 77% 63% 87% 76% 61% 79% 97% 70% 97% 68% 91% 90% 61% 88% 80% 62% 73% 89% 68% 87% 66% 94% 83% 81% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose240.5755
GSM1296119B_lesional_pre-dose395.7264
GSM1296076C_lesional_pre-dose372.564
GSM1296092D_lesional_pre-dose458.2767
GSM1296103E_lesional_pre-dose367.2362
GSM1296078F_lesional_pre-dose1136.8981
GSM1296107G_lesional_pre-dose2701.6292
GSM1296109H_lesional_pre-dose425.7664
GSM1296080I_lesional_pre-dose323.3461
GSM1296090J_lesional_pre-dose428.2766
GSM1296074K_lesional_pre-dose470.8668
GSM1296111L_lesional_pre-dose818.1776
GSM1296099M_lesional_pre-dose336.9560
GSM1296086O_lesional_pre-dose629.5972
GSM1296117P_lesional_pre-dose338.161
GSM1296113Q_lesional_pre-dose304.9458
GSM1296096R_lesional_pre-dose348.2862
GSM1296105S_lesional_pre-dose2302.7791
GSM1296098T_lesional_pre-dose24455
GSM1296101U_lesional_pre-dose335.3460
GSM1296121V_lesional_pre-dose489.3967
GSM1296088W_lesional_pre-dose378.3963
GSM1296082X_lesional_pre-dose245.3357
GSM1296115Y_lesional_pre-dose557.9970
GSM1296084Z_lesional_pre-dose275.4758
GSM1296072B_lesional_day8524.7268
GSM1296069L_lesional_day81409.0485
GSM1296071P_lesional_day8780.3875
GSM1296070Y_lesional_day8960.7979
GSM1296073V_lesional_day8655.4873
GSM1296034A_lesional_day15343.5160
GSM1296041G_lesional_day151828.3588
GSM1296035R_lesional_day15300.9259
GSM1296038U_lesional_day15965.7778
GSM1296047B_lesional_day15398.1163
GSM1296039E_lesional_day15291.7759
GSM1296042H_lesional_day151120.0181
GSM1296043L_lesional_day15983.5679
GSM1296037M_lesional_day15409.1664
GSM1296046P_lesional_day15545.4769
GSM1296044Q_lesional_day153263.8695
GSM1296045Y_lesional_day151328.9584
GSM1296025C_lesional_day152372.9291
GSM1296033D_lesional_day15642.9772
GSM1296027I_lesional_day151192.8481
GSM1296032J_lesional_day153322.3995
GSM1296024K_lesional_day152058.0989
GSM1296031W_lesional_day153005.4694
GSM1296028X_lesional_day15417.3864
GSM1296029Z_lesional_day15613.4371
GSM1296026F_lesional_day15759.8375
GSM1296030O_lesional_day15673.6673
GSM1296040S_lesional_day151249.4183
GSM1296036T_lesional_day15305.0858
GSM1296048V_lesional_day15634.9772
GSM1296059A_lesional_day43311.1860
GSM1296066G_lesional_day431554.6686
GSM1296060R_lesional_day43589.3870
GSM1296063U_lesional_day432314.7691
GSM1296064E_lesional_day43564.0570
GSM1296067H_lesional_day431136.382
GSM1296062M_lesional_day43332.6760
GSM1296068Q_lesional_day437961.2699
GSM1296050C_lesional_day435150.2398
GSM1296057D_lesional_day431652.2887
GSM1296052I_lesional_day431650.6686
GSM1296054J_lesional_day43460.1566
GSM1296049K_lesional_day432055.4489
GSM1296055W_lesional_day431637.887
GSM1296053X_lesional_day43453.0566
GSM1296058Z_lesional_day43524.168
GSM1296051F_lesional_day431239.3982
GSM1296056O_lesional_day43560.3970
GSM1296065S_lesional_day435610.399
GSM1296061T_lesional_day431324.0584
GSM1296095A_non-lesional_pre-dose849.3477
GSM1296120B_non-lesional_pre-dose383.1663
GSM1296077C_non-lesional_pre-dose1724.187
GSM1296093D_non-lesional_pre-dose852.2476
GSM1296104E_non-lesional_pre-dose343.9261
GSM1296079F_non-lesional_pre-dose1036.7279
GSM1296108G_non-lesional_pre-dose4327.5797
GSM1296110H_non-lesional_pre-dose593.870
GSM1296081I_non-lesional_pre-dose4635.4897
GSM1296091J_non-lesional_pre-dose490.8668
GSM1296075K_non-lesional_pre-dose2465.891
GSM1296112L_non-lesional_pre-dose1896.0190
GSM1296100M_non-lesional_pre-dose340.4961
GSM1296087O_non-lesional_pre-dose1949.0388
GSM1296118P_non-lesional_pre-dose1003.0380
GSM1296114Q_non-lesional_pre-dose369.1162
GSM1296097R_non-lesional_pre-dose672.3573
GSM1296106S_non-lesional_pre-dose1933.9689
GSM1296102U_non-lesional_pre-dose518.7368
GSM1296122V_non-lesional_pre-dose1652.887
GSM1296089W_non-lesional_pre-dose48066
GSM1296083X_non-lesional_pre-dose3200.6294
GSM1296116Y_non-lesional_pre-dose1264.4183
GSM1296085Z_non-lesional_pre-dose1124.7481