ProfileGDS5420 / 225280_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 73% 64% 61% 65% 72% 58% 63% 70% 67% 64% 62% 60% 68% 64% 64% 63% 63% 71% 73% 73% 69% 65% 57% 67% 66% 69% 65% 67% 69% 64% 81% 61% 67% 72% 70% 62% 67% 61% 77% 67% 64% 74% 78% 67% 62% 73% 75% 74% 70% 71% 65% 67% 73% 72% 69% 71% 62% 69% 67% 64% 73% 75% 65% 70% 75% 60% 73% 71% 75% 72% 75% 63% 70% 67% 76% 65% 69% 78% 78% 66% 70% 67% 72% 79% 67% 67% 67% 83% 67% 73% 64% 68% 77% 78% 71% 75% 81% 73% 70% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose704.9673
GSM1296119B_lesional_pre-dose399.6764
GSM1296076C_lesional_pre-dose312.4761
GSM1296092D_lesional_pre-dose416.8765
GSM1296103E_lesional_pre-dose668.1872
GSM1296078F_lesional_pre-dose248.2958
GSM1296107G_lesional_pre-dose379.4863
GSM1296109H_lesional_pre-dose591.7570
GSM1296080I_lesional_pre-dose478.167
GSM1296090J_lesional_pre-dose375.8364
GSM1296074K_lesional_pre-dose330.5962
GSM1296111L_lesional_pre-dose328.4560
GSM1296099M_lesional_pre-dose513.1768
GSM1296086O_lesional_pre-dose392.964
GSM1296117P_lesional_pre-dose409.6264
GSM1296113Q_lesional_pre-dose391.7463
GSM1296096R_lesional_pre-dose383.1763
GSM1296105S_lesional_pre-dose624.2771
GSM1296098T_lesional_pre-dose677.2873
GSM1296101U_lesional_pre-dose704.3473
GSM1296121V_lesional_pre-dose536.4269
GSM1296088W_lesional_pre-dose438.0565
GSM1296082X_lesional_pre-dose247.257
GSM1296115Y_lesional_pre-dose492.5567
GSM1296084Z_lesional_pre-dose443.6766
GSM1296072B_lesional_day8535.669
GSM1296069L_lesional_day8435.8965
GSM1296071P_lesional_day8504.1867
GSM1296070Y_lesional_day8534.9669
GSM1296073V_lesional_day8397.6364
GSM1296034A_lesional_day151088.4581
GSM1296041G_lesional_day15339.7161
GSM1296035R_lesional_day15481.0867
GSM1296038U_lesional_day15645.7972
GSM1296047B_lesional_day15566.8470
GSM1296039E_lesional_day15343.3262
GSM1296042H_lesional_day15480.7367
GSM1296043L_lesional_day15350.761
GSM1296037M_lesional_day15894.7977
GSM1296046P_lesional_day15507.2567
GSM1296044Q_lesional_day15415.9564
GSM1296045Y_lesional_day15715.7274
GSM1296025C_lesional_day15929.1378
GSM1296033D_lesional_day15488.9167
GSM1296027I_lesional_day15346.1262
GSM1296032J_lesional_day15700.3573
GSM1296024K_lesional_day15786.4475
GSM1296031W_lesional_day15741.1374
GSM1296028X_lesional_day15571.1170
GSM1296029Z_lesional_day15629.9871
GSM1296026F_lesional_day15406.8765
GSM1296030O_lesional_day15480.7467
GSM1296040S_lesional_day15689.4173
GSM1296036T_lesional_day15681.7872
GSM1296048V_lesional_day15523.7169
GSM1296059A_lesional_day43626.1271
GSM1296066G_lesional_day43372.6762
GSM1296060R_lesional_day43536.5369
GSM1296063U_lesional_day43478.7267
GSM1296064E_lesional_day43385.4664
GSM1296067H_lesional_day43679.1973
GSM1296062M_lesional_day43777.1175
GSM1296068Q_lesional_day43451.965
GSM1296050C_lesional_day43558.9870
GSM1296057D_lesional_day43781.7675
GSM1296052I_lesional_day43297.860
GSM1296054J_lesional_day43706.3573
GSM1296049K_lesional_day43593.8871
GSM1296055W_lesional_day43771.9675
GSM1296053X_lesional_day43656.8172
GSM1296058Z_lesional_day43787.6575
GSM1296051F_lesional_day43351.6863
GSM1296056O_lesional_day43564.270
GSM1296065S_lesional_day43497.2667
GSM1296061T_lesional_day43818.2176
GSM1296095A_non-lesional_pre-dose420.5565
GSM1296120B_non-lesional_pre-dose539.7869
GSM1296077C_non-lesional_pre-dose956.2178
GSM1296093D_non-lesional_pre-dose941.1278
GSM1296104E_non-lesional_pre-dose441.9666
GSM1296079F_non-lesional_pre-dose582.0870
GSM1296108G_non-lesional_pre-dose473.6867
GSM1296110H_non-lesional_pre-dose664.4972
GSM1296081I_non-lesional_pre-dose1031.8279
GSM1296091J_non-lesional_pre-dose463.4267
GSM1296075K_non-lesional_pre-dose446.5767
GSM1296112L_non-lesional_pre-dose505.2767
GSM1296100M_non-lesional_pre-dose1281.3983
GSM1296087O_non-lesional_pre-dose477.6267
GSM1296118P_non-lesional_pre-dose687.0773
GSM1296114Q_non-lesional_pre-dose414.6964
GSM1296097R_non-lesional_pre-dose503.4168
GSM1296106S_non-lesional_pre-dose859.1177
GSM1296102U_non-lesional_pre-dose960.1778
GSM1296122V_non-lesional_pre-dose627.6471
GSM1296089W_non-lesional_pre-dose767.3275
GSM1296083X_non-lesional_pre-dose1144.0981
GSM1296116Y_non-lesional_pre-dose675.3773
GSM1296085Z_non-lesional_pre-dose591.7670