ProfileGDS5420 / 225029_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 78% 93% 90% 94% 91% 89% 90% 84% 77% 93% 91% 91% 92% 91% 92% 91% 91% 87% 76% 89% 91% 86% 93% 90% 91% 94% 93% 90% 91% 91% 75% 91% 92% 91% 93% 94% 91% 92% 92% 90% 92% 89% 76% 92% 91% 91% 77% 90% 88% 91% 83% 90% 90% 78% 92% 92% 90% 91% 93% 94% 89% 81% 90% 86% 92% 92% 84% 76% 92% 82% 93% 87% 92% 93% 72% 94% 93% 81% 84% 94% 79% 90% 87% 82% 94% 89% 90% 91% 92% 89% 91% 93% 90% 88% 91% 93% 79% 90% 93% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose924.3278
GSM1296119B_lesional_pre-dose2885.593
GSM1296076C_lesional_pre-dose2407.3890
GSM1296092D_lesional_pre-dose3341.7894
GSM1296103E_lesional_pre-dose2288.0891
GSM1296078F_lesional_pre-dose2188.789
GSM1296107G_lesional_pre-dose2184.0490
GSM1296109H_lesional_pre-dose1382.8984
GSM1296080I_lesional_pre-dose884.9177
GSM1296090J_lesional_pre-dose3131.9993
GSM1296074K_lesional_pre-dose2582.5791
GSM1296111L_lesional_pre-dose2296.0491
GSM1296099M_lesional_pre-dose2513.8692
GSM1296086O_lesional_pre-dose2549.7391
GSM1296117P_lesional_pre-dose2421.1192
GSM1296113Q_lesional_pre-dose2143.5891
GSM1296096R_lesional_pre-dose2334.5391
GSM1296105S_lesional_pre-dose1683.8187
GSM1296098T_lesional_pre-dose811.7376
GSM1296101U_lesional_pre-dose1906.5689
GSM1296121V_lesional_pre-dose2389.4291
GSM1296088W_lesional_pre-dose1618.4786
GSM1296082X_lesional_pre-dose3135.0293
GSM1296115Y_lesional_pre-dose2143.2190
GSM1296084Z_lesional_pre-dose2360.2591
GSM1296072B_lesional_day82940.1594
GSM1296069L_lesional_day82556.2293
GSM1296071P_lesional_day81922.6990
GSM1296070Y_lesional_day82196.7191
GSM1296073V_lesional_day82574.3291
GSM1296034A_lesional_day15795.6875
GSM1296041G_lesional_day152292.4991
GSM1296035R_lesional_day152555.6992
GSM1296038U_lesional_day152406.1591
GSM1296047B_lesional_day152567.1293
GSM1296039E_lesional_day153401.1294
GSM1296042H_lesional_day152191.191
GSM1296043L_lesional_day152277.2492
GSM1296037M_lesional_day152650.0692
GSM1296046P_lesional_day152032.4390
GSM1296044Q_lesional_day152277.5392
GSM1296045Y_lesional_day15191489
GSM1296025C_lesional_day15825.5576
GSM1296033D_lesional_day152528.5992
GSM1296027I_lesional_day152343.1391
GSM1296032J_lesional_day152292.4891
GSM1296024K_lesional_day15882.4877
GSM1296031W_lesional_day152121.9290
GSM1296028X_lesional_day151879.3488
GSM1296029Z_lesional_day152352.4491
GSM1296026F_lesional_day151311.1483
GSM1296030O_lesional_day152259.5190
GSM1296040S_lesional_day152147.1690
GSM1296036T_lesional_day15922.178
GSM1296048V_lesional_day152626.4192
GSM1296059A_lesional_day432587.1392
GSM1296066G_lesional_day432145.5190
GSM1296060R_lesional_day432288.8991
GSM1296063U_lesional_day432987.4193
GSM1296064E_lesional_day433394.8994
GSM1296067H_lesional_day431877.689
GSM1296062M_lesional_day431126.9281
GSM1296068Q_lesional_day43196390
GSM1296050C_lesional_day431557.5586
GSM1296057D_lesional_day432458.4692
GSM1296052I_lesional_day432547.3992
GSM1296054J_lesional_day431313.8484
GSM1296049K_lesional_day43843.8176
GSM1296055W_lesional_day432539.2392
GSM1296053X_lesional_day431234.882
GSM1296058Z_lesional_day432816.5293
GSM1296051F_lesional_day431807.6387
GSM1296056O_lesional_day432685.4492
GSM1296065S_lesional_day432747.493
GSM1296061T_lesional_day43663.6372
GSM1296095A_non-lesional_pre-dose3161.8894
GSM1296120B_non-lesional_pre-dose2743.2593
GSM1296077C_non-lesional_pre-dose1161.3381
GSM1296093D_non-lesional_pre-dose1312.8184
GSM1296104E_non-lesional_pre-dose3425.6894
GSM1296079F_non-lesional_pre-dose996.679
GSM1296108G_non-lesional_pre-dose2061.6990
GSM1296110H_non-lesional_pre-dose1633.4587
GSM1296081I_non-lesional_pre-dose1260.6982
GSM1296091J_non-lesional_pre-dose3109.4194
GSM1296075K_non-lesional_pre-dose2045.4689
GSM1296112L_non-lesional_pre-dose1979.3890
GSM1296100M_non-lesional_pre-dose2388.191
GSM1296087O_non-lesional_pre-dose2767.4392
GSM1296118P_non-lesional_pre-dose1845.4289
GSM1296114Q_non-lesional_pre-dose2260.2291
GSM1296097R_non-lesional_pre-dose2953.3893
GSM1296106S_non-lesional_pre-dose2107.390
GSM1296102U_non-lesional_pre-dose1705.0688
GSM1296122V_non-lesional_pre-dose2293.6491
GSM1296089W_non-lesional_pre-dose2568.4693
GSM1296083X_non-lesional_pre-dose991.0179
GSM1296116Y_non-lesional_pre-dose1917.2890
GSM1296085Z_non-lesional_pre-dose2719.2393