ProfileGDS5420 / 224744_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 87% 88% 80% 75% 87% 84% 79% 51% 83% 86% 89% 80% 82% 87% 81% 82% 73% 52% 71% 83% 77% 84% 90% 74% 82% 88% 83% 86% 87% 58% 89% 79% 80% 83% 83% 84% 85% 71% 85% 83% 86% 58% 76% 70% 70% 61% 76% 65% 67% 66% 67% 74% 59% 84% 78% 86% 78% 86% 86% 75% 67% 89% 83% 73% 61% 54% 59% 86% 64% 76% 82% 81% 84% 58% 82% 83% 71% 56% 78% 67% 81% 75% 55% 76% 81% 83% 73% 70% 82% 79% 77% 75% 67% 80% 73% 61% 83% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose315.0659
GSM1296119B_lesional_pre-dose1653.8487
GSM1296076C_lesional_pre-dose2013.988
GSM1296092D_lesional_pre-dose1087.5280
GSM1296103E_lesional_pre-dose807.4375
GSM1296078F_lesional_pre-dose1820.5687
GSM1296107G_lesional_pre-dose1338.1384
GSM1296109H_lesional_pre-dose952.3479
GSM1296080I_lesional_pre-dose172.3951
GSM1296090J_lesional_pre-dose1364.4683
GSM1296074K_lesional_pre-dose1665.986
GSM1296111L_lesional_pre-dose2023.4789
GSM1296099M_lesional_pre-dose1054.6580
GSM1296086O_lesional_pre-dose1223.8682
GSM1296117P_lesional_pre-dose1729.3987
GSM1296113Q_lesional_pre-dose1054.3181
GSM1296096R_lesional_pre-dose1250.5582
GSM1296105S_lesional_pre-dose714.0773
GSM1296098T_lesional_pre-dose196.3252
GSM1296101U_lesional_pre-dose607.2471
GSM1296121V_lesional_pre-dose1299.4183
GSM1296088W_lesional_pre-dose916.1277
GSM1296082X_lesional_pre-dose1464.0984
GSM1296115Y_lesional_pre-dose2064.2190
GSM1296084Z_lesional_pre-dose743.5874
GSM1296072B_lesional_day81187.882
GSM1296069L_lesional_day81698.7488
GSM1296071P_lesional_day81211.4383
GSM1296070Y_lesional_day81506.5886
GSM1296073V_lesional_day81731.6187
GSM1296034A_lesional_day15297.8858
GSM1296041G_lesional_day151952.2789
GSM1296035R_lesional_day15978.7379
GSM1296038U_lesional_day151061.780
GSM1296047B_lesional_day151224.0383
GSM1296039E_lesional_day151263.6283
GSM1296042H_lesional_day151303.4184
GSM1296043L_lesional_day151438.585
GSM1296037M_lesional_day15625.371
GSM1296046P_lesional_day151441.8885
GSM1296044Q_lesional_day151210.8683
GSM1296045Y_lesional_day151537.6586
GSM1296025C_lesional_day15278.0658
GSM1296033D_lesional_day15839.3276
GSM1296027I_lesional_day15560.470
GSM1296032J_lesional_day15598.8870
GSM1296024K_lesional_day15337.1461
GSM1296031W_lesional_day15821.1476
GSM1296028X_lesional_day15437.6365
GSM1296029Z_lesional_day15496.7467
GSM1296026F_lesional_day15431.6366
GSM1296030O_lesional_day15460.7767
GSM1296040S_lesional_day15729.4874
GSM1296036T_lesional_day15313.5659
GSM1296048V_lesional_day151401.5784
GSM1296059A_lesional_day43948.1778
GSM1296066G_lesional_day431518.0386
GSM1296060R_lesional_day43956.6378
GSM1296063U_lesional_day431593.8586
GSM1296064E_lesional_day431621.4186
GSM1296067H_lesional_day43765.6875
GSM1296062M_lesional_day43488.0967
GSM1296068Q_lesional_day431887.0789
GSM1296050C_lesional_day431301.3183
GSM1296057D_lesional_day43701.3773
GSM1296052I_lesional_day43332.3861
GSM1296054J_lesional_day4323154
GSM1296049K_lesional_day43289.1659
GSM1296055W_lesional_day431528.2786
GSM1296053X_lesional_day43421.8664
GSM1296058Z_lesional_day43857.4976
GSM1296051F_lesional_day431203.5682
GSM1296056O_lesional_day431136.9381
GSM1296065S_lesional_day431385.5484
GSM1296061T_lesional_day43295.358
GSM1296095A_non-lesional_pre-dose1217.6682
GSM1296120B_non-lesional_pre-dose1281.783
GSM1296077C_non-lesional_pre-dose599.171
GSM1296093D_non-lesional_pre-dose258.9356
GSM1296104E_non-lesional_pre-dose927.7178
GSM1296079F_non-lesional_pre-dose483.2267
GSM1296108G_non-lesional_pre-dose1143.4881
GSM1296110H_non-lesional_pre-dose766.5875
GSM1296081I_non-lesional_pre-dose218.555
GSM1296091J_non-lesional_pre-dose861.9376
GSM1296075K_non-lesional_pre-dose1183.9181
GSM1296112L_non-lesional_pre-dose1233.4883
GSM1296100M_non-lesional_pre-dose679.7773
GSM1296087O_non-lesional_pre-dose546.7270
GSM1296118P_non-lesional_pre-dose1153.4282
GSM1296114Q_non-lesional_pre-dose966.9679
GSM1296097R_non-lesional_pre-dose885.277
GSM1296106S_non-lesional_pre-dose784.1175
GSM1296102U_non-lesional_pre-dose506.8567
GSM1296122V_non-lesional_pre-dose1019.9780
GSM1296089W_non-lesional_pre-dose694.4273
GSM1296083X_non-lesional_pre-dose343.1661
GSM1296116Y_non-lesional_pre-dose1214.2183
GSM1296085Z_non-lesional_pre-dose558.1969