ProfileGDS5420 / 224299_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 28% 19% 31% 23% 35% 32% 26% 40% 29% 24% 40% 39% 30% 13% 31% 17% 33% 36% 8% 33% 34% 28% 26% 38% 30% 16% 25% 33% 29% 30% 29% 3% 29% 34% 22% 17% 29% 31% 38% 19% 33% 37% 42% 21% 31% 32% 37% 29% 29% 34% 36% 7% 35% 28% 25% 32% 23% 23% 31% 30% 36% 30% 36% 43% 21% 27% 34% 31% 27% 29% 32% 35% 33% 23% 31% 25% 32% 38% 25% 38% 38% 32% 35% 36% 13% 28% 36% 37% 19% 40% 33% 30% 39% 36% 32% 37% 37% 33% 16% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose40.6728
GSM1296119B_lesional_pre-dose25.7419
GSM1296076C_lesional_pre-dose51.5331
GSM1296092D_lesional_pre-dose2523
GSM1296103E_lesional_pre-dose61.7435
GSM1296078F_lesional_pre-dose52.6432
GSM1296107G_lesional_pre-dose43.9526
GSM1296109H_lesional_pre-dose99.3540
GSM1296080I_lesional_pre-dose39.8829
GSM1296090J_lesional_pre-dose28.0824
GSM1296074K_lesional_pre-dose78.8240
GSM1296111L_lesional_pre-dose98.639
GSM1296099M_lesional_pre-dose49.0830
GSM1296086O_lesional_pre-dose13.2813
GSM1296117P_lesional_pre-dose61.4731
GSM1296113Q_lesional_pre-dose28.2317
GSM1296096R_lesional_pre-dose56.0233
GSM1296105S_lesional_pre-dose73.1136
GSM1296098T_lesional_pre-dose12.258
GSM1296101U_lesional_pre-dose56.7833
GSM1296121V_lesional_pre-dose67.634
GSM1296088W_lesional_pre-dose39.5128
GSM1296082X_lesional_pre-dose31.7926
GSM1296115Y_lesional_pre-dose87.4938
GSM1296084Z_lesional_pre-dose49.9630
GSM1296072B_lesional_day819.1416
GSM1296069L_lesional_day843.0725
GSM1296071P_lesional_day874.8433
GSM1296070Y_lesional_day855.4829
GSM1296073V_lesional_day850.6230
GSM1296034A_lesional_day1547.3929
GSM1296041G_lesional_day154.13
GSM1296035R_lesional_day1537.7429
GSM1296038U_lesional_day1560.334
GSM1296047B_lesional_day1533.2222
GSM1296039E_lesional_day1519.9517
GSM1296042H_lesional_day1554.4929
GSM1296043L_lesional_day1562.6331
GSM1296037M_lesional_day1585.7538
GSM1296046P_lesional_day1529.519
GSM1296044Q_lesional_day1571.933
GSM1296045Y_lesional_day1591.737
GSM1296025C_lesional_day1599.6842
GSM1296033D_lesional_day1523.3321
GSM1296027I_lesional_day1540.7131
GSM1296032J_lesional_day1553.3332
GSM1296024K_lesional_day1568.4537
GSM1296031W_lesional_day1545.3329
GSM1296028X_lesional_day1541.429
GSM1296029Z_lesional_day1558.4334
GSM1296026F_lesional_day1570.8936
GSM1296030O_lesional_day155.687
GSM1296040S_lesional_day1567.935
GSM1296036T_lesional_day1545.2128
GSM1296048V_lesional_day1537.8125
GSM1296059A_lesional_day4350.3132
GSM1296066G_lesional_day4337.1223
GSM1296060R_lesional_day4327.2523
GSM1296063U_lesional_day4352.631
GSM1296064E_lesional_day434630
GSM1296067H_lesional_day4385.7436
GSM1296062M_lesional_day4346.9330
GSM1296068Q_lesional_day4389.3136
GSM1296050C_lesional_day43113.2743
GSM1296057D_lesional_day4322.421
GSM1296052I_lesional_day4332.2727
GSM1296054J_lesional_day4363.2434
GSM1296049K_lesional_day4348.6831
GSM1296055W_lesional_day4341.127
GSM1296053X_lesional_day4342.9929
GSM1296058Z_lesional_day4348.6532
GSM1296051F_lesional_day4362.7235
GSM1296056O_lesional_day4352.2833
GSM1296065S_lesional_day4330.0623
GSM1296061T_lesional_day4354.1531
GSM1296095A_non-lesional_pre-dose32.0525
GSM1296120B_non-lesional_pre-dose65.3432
GSM1296077C_non-lesional_pre-dose74.838
GSM1296093D_non-lesional_pre-dose35.1925
GSM1296104E_non-lesional_pre-dose82.738
GSM1296079F_non-lesional_pre-dose76.538
GSM1296108G_non-lesional_pre-dose6032
GSM1296110H_non-lesional_pre-dose82.2935
GSM1296081I_non-lesional_pre-dose61.6536
GSM1296091J_non-lesional_pre-dose11.9613
GSM1296075K_non-lesional_pre-dose39.2828
GSM1296112L_non-lesional_pre-dose94.2636
GSM1296100M_non-lesional_pre-dose78.4537
GSM1296087O_non-lesional_pre-dose20.3619
GSM1296118P_non-lesional_pre-dose113.5540
GSM1296114Q_non-lesional_pre-dose70.0733
GSM1296097R_non-lesional_pre-dose46.6730
GSM1296106S_non-lesional_pre-dose94.3939
GSM1296102U_non-lesional_pre-dose75.0636
GSM1296122V_non-lesional_pre-dose65.5932
GSM1296089W_non-lesional_pre-dose81.7337
GSM1296083X_non-lesional_pre-dose71.2937
GSM1296116Y_non-lesional_pre-dose72.9233
GSM1296085Z_non-lesional_pre-dose17.2316