ProfileGDS5420 / 223813_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 21% 29% 22% 18% 21% 19% 17% 24% 19% 20% 22% 22% 21% 23% 25% 17% 24% 20% 33% 29% 23% 18% 29% 15% 30% 23% 7% 21% 12% 26% 8% 18% 26% 19% 29% 6% 27% 29% 30% 24% 11% 18% 18% 16% 1% 22% 32% 27% 15% 36% 35% 33% 26% 32% 29% 28% 27% 27% 20% 26% 42% 19% 17% 15% 24% 32% 28% 32% 30% 15% 36% 32% 27% 23% 43% 19% 13% 27% 13% 32% 24% 13% 15% 8% 24% 29% 17% 32% 15% 24% 19% 22% 18% 27% 22% 18% 9% 25% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose24.7621
GSM1296119B_lesional_pre-dose50.7229
GSM1296076C_lesional_pre-dose29.2322
GSM1296092D_lesional_pre-dose17.8518
GSM1296103E_lesional_pre-dose24.4121
GSM1296078F_lesional_pre-dose22.8319
GSM1296107G_lesional_pre-dose22.4717
GSM1296109H_lesional_pre-dose36.3924
GSM1296080I_lesional_pre-dose19.8319
GSM1296090J_lesional_pre-dose21.420
GSM1296074K_lesional_pre-dose24.0822
GSM1296111L_lesional_pre-dose34.3922
GSM1296099M_lesional_pre-dose25.821
GSM1296086O_lesional_pre-dose28.1123
GSM1296117P_lesional_pre-dose43.125
GSM1296113Q_lesional_pre-dose27.0117
GSM1296096R_lesional_pre-dose28.8324
GSM1296105S_lesional_pre-dose24.120
GSM1296098T_lesional_pre-dose65.3533
GSM1296101U_lesional_pre-dose45.5529
GSM1296121V_lesional_pre-dose32.2623
GSM1296088W_lesional_pre-dose19.6418
GSM1296082X_lesional_pre-dose40.4129
GSM1296115Y_lesional_pre-dose17.9615
GSM1296084Z_lesional_pre-dose49.830
GSM1296072B_lesional_day832.6623
GSM1296069L_lesional_day89.177
GSM1296071P_lesional_day832.5921
GSM1296070Y_lesional_day815.2812
GSM1296073V_lesional_day839.2626
GSM1296034A_lesional_day158.548
GSM1296041G_lesional_day1524.4318
GSM1296035R_lesional_day1531.8826
GSM1296038U_lesional_day1520.7219
GSM1296047B_lesional_day1553.2629
GSM1296039E_lesional_day156.736
GSM1296042H_lesional_day1547.6127
GSM1296043L_lesional_day1555.1729
GSM1296037M_lesional_day1551.7130
GSM1296046P_lesional_day1539.0324
GSM1296044Q_lesional_day1514.0211
GSM1296045Y_lesional_day1528.9618
GSM1296025C_lesional_day1521.7118
GSM1296033D_lesional_day1516.0216
GSM1296027I_lesional_day150.691
GSM1296032J_lesional_day1525.8622
GSM1296024K_lesional_day1548.8832
GSM1296031W_lesional_day1540.9527
GSM1296028X_lesional_day1515.4815
GSM1296029Z_lesional_day1570.5936
GSM1296026F_lesional_day1566.6335
GSM1296030O_lesional_day1546.5533
GSM1296040S_lesional_day1537.9826
GSM1296036T_lesional_day1560.8432
GSM1296048V_lesional_day1549.7729
GSM1296059A_lesional_day4337.1828
GSM1296066G_lesional_day4346.9327
GSM1296060R_lesional_day4337.3427
GSM1296063U_lesional_day4323.320
GSM1296064E_lesional_day4335.8426
GSM1296067H_lesional_day43118.0742
GSM1296062M_lesional_day4319.9319
GSM1296068Q_lesional_day4326.3317
GSM1296050C_lesional_day4318.6315
GSM1296057D_lesional_day4328.5324
GSM1296052I_lesional_day4346.4332
GSM1296054J_lesional_day4342.828
GSM1296049K_lesional_day4353.3732
GSM1296055W_lesional_day4350.6730
GSM1296053X_lesional_day4315.6815
GSM1296058Z_lesional_day4363.0536
GSM1296051F_lesional_day4354.8532
GSM1296056O_lesional_day4333.8327
GSM1296065S_lesional_day4328.4123
GSM1296061T_lesional_day43116.8643
GSM1296095A_non-lesional_pre-dose20.8719
GSM1296120B_non-lesional_pre-dose17.1513
GSM1296077C_non-lesional_pre-dose37.8927
GSM1296093D_non-lesional_pre-dose14.6713
GSM1296104E_non-lesional_pre-dose54.4432
GSM1296079F_non-lesional_pre-dose32.4924
GSM1296108G_non-lesional_pre-dose15.4113
GSM1296110H_non-lesional_pre-dose20.1915
GSM1296081I_non-lesional_pre-dose7.258
GSM1296091J_non-lesional_pre-dose28.3724
GSM1296075K_non-lesional_pre-dose42.1729
GSM1296112L_non-lesional_pre-dose27.6417
GSM1296100M_non-lesional_pre-dose
GSM1296087O_non-lesional_pre-dose46.5432
GSM1296118P_non-lesional_pre-dose22.0515
GSM1296114Q_non-lesional_pre-dose41.2324
GSM1296097R_non-lesional_pre-dose20.7919
GSM1296106S_non-lesional_pre-dose29.6522
GSM1296102U_non-lesional_pre-dose20.4818
GSM1296122V_non-lesional_pre-dose46.8327
GSM1296089W_non-lesional_pre-dose30.0622
GSM1296083X_non-lesional_pre-dose19.4418
GSM1296116Y_non-lesional_pre-dose13.469
GSM1296085Z_non-lesional_pre-dose33.4625