ProfileGDS5420 / 223809_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 25% 59% 57% 52% 33% 39% 38% 28% 27% 56% 59% 53% 40% 53% 52% 57% 44% 27% 20% 43% 45% 38% 53% 51% 28% 55% 58% 59% 53% 63% 26% 52% 55% 48% 48% 63% 48% 45% 32% 56% 47% 57% 11% 42% 41% 22% 43% 47% 37% 45% 35% 47% 26% 23% 60% 32% 35% 54% 65% 53% 50% 38% 42% 45% 45% 43% 31% 37% 49% 32% 43% 47% 61% 40% 39% 47% 48% 31% 43% 18% 36% 41% 5% 21% 43% 26% 25% 37% 27% 48% 40% 32% 52% 41% 12% 40% 26% 16% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose31.6325
GSM1296119B_lesional_pre-dose294.3859
GSM1296076C_lesional_pre-dose249.4557
GSM1296092D_lesional_pre-dose176.2652
GSM1296103E_lesional_pre-dose53.9633
GSM1296078F_lesional_pre-dose80.4939
GSM1296107G_lesional_pre-dose92.938
GSM1296109H_lesional_pre-dose47.4828
GSM1296080I_lesional_pre-dose33.6727
GSM1296090J_lesional_pre-dose233.9556
GSM1296074K_lesional_pre-dose273.6859
GSM1296111L_lesional_pre-dose215.7353
GSM1296099M_lesional_pre-dose93.1140
GSM1296086O_lesional_pre-dose193.6653
GSM1296117P_lesional_pre-dose209.2752
GSM1296113Q_lesional_pre-dose281.2957
GSM1296096R_lesional_pre-dose117.1144
GSM1296105S_lesional_pre-dose39.6927
GSM1296098T_lesional_pre-dose29.3820
GSM1296101U_lesional_pre-dose113.6843
GSM1296121V_lesional_pre-dose135.1645
GSM1296088W_lesional_pre-dose75.0138
GSM1296082X_lesional_pre-dose183.3553
GSM1296115Y_lesional_pre-dose192.9151
GSM1296084Z_lesional_pre-dose43.9628
GSM1296072B_lesional_day8247.8155
GSM1296069L_lesional_day8306.258
GSM1296071P_lesional_day8314.3959
GSM1296070Y_lesional_day8223.7653
GSM1296073V_lesional_day8375.6463
GSM1296034A_lesional_day1539.8326
GSM1296041G_lesional_day15199.6452
GSM1296035R_lesional_day15240.8855
GSM1296038U_lesional_day15148.2148
GSM1296047B_lesional_day15164.2648
GSM1296039E_lesional_day15365.9563
GSM1296042H_lesional_day15167.4748
GSM1296043L_lesional_day15147.0145
GSM1296037M_lesional_day1558.2832
GSM1296046P_lesional_day15269.756
GSM1296044Q_lesional_day15169.4747
GSM1296045Y_lesional_day15290.6457
GSM1296025C_lesional_day1512.4111
GSM1296033D_lesional_day15101.242
GSM1296027I_lesional_day1584.8641
GSM1296032J_lesional_day1526.7522
GSM1296024K_lesional_day15103.5643
GSM1296031W_lesional_day15149.5947
GSM1296028X_lesional_day1570.5437
GSM1296029Z_lesional_day15121.0445
GSM1296026F_lesional_day1565.9835
GSM1296030O_lesional_day15123.4447
GSM1296040S_lesional_day1537.1226
GSM1296036T_lesional_day1532.2623
GSM1296048V_lesional_day15318.6460
GSM1296059A_lesional_day4351.4832
GSM1296066G_lesional_day4377.8835
GSM1296060R_lesional_day43218.6654
GSM1296063U_lesional_day43412.0765
GSM1296064E_lesional_day43193.2353
GSM1296067H_lesional_day43196.8250
GSM1296062M_lesional_day4381.4538
GSM1296068Q_lesional_day43128.642
GSM1296050C_lesional_day43125.1745
GSM1296057D_lesional_day43127.1845
GSM1296052I_lesional_day4399.2743
GSM1296054J_lesional_day4351.7131
GSM1296049K_lesional_day4372.0537
GSM1296055W_lesional_day43177.7849
GSM1296053X_lesional_day4352.5332
GSM1296058Z_lesional_day43104.2743
GSM1296051F_lesional_day43132.5947
GSM1296056O_lesional_day43317.7861
GSM1296065S_lesional_day4395.8440
GSM1296061T_lesional_day4391.6639
GSM1296095A_non-lesional_pre-dose133.3247
GSM1296120B_non-lesional_pre-dose167.248
GSM1296077C_non-lesional_pre-dose46.2231
GSM1296093D_non-lesional_pre-dose
GSM1296104E_non-lesional_pre-dose111.6243
GSM1296079F_non-lesional_pre-dose21.9618
GSM1296108G_non-lesional_pre-dose76.8536
GSM1296110H_non-lesional_pre-dose119.5541
GSM1296081I_non-lesional_pre-dose4.65
GSM1296091J_non-lesional_pre-dose23.5321
GSM1296075K_non-lesional_pre-dose103.7543
GSM1296112L_non-lesional_pre-dose50.1726
GSM1296100M_non-lesional_pre-dose33.0725
GSM1296087O_non-lesional_pre-dose62.137
GSM1296118P_non-lesional_pre-dose49.727
GSM1296114Q_non-lesional_pre-dose168.9848
GSM1296097R_non-lesional_pre-dose92.2240
GSM1296106S_non-lesional_pre-dose57.5132
GSM1296102U_non-lesional_pre-dose213.9752
GSM1296122V_non-lesional_pre-dose113.7641
GSM1296089W_non-lesional_pre-dose13.1512
GSM1296083X_non-lesional_pre-dose89.7440
GSM1296116Y_non-lesional_pre-dose50.2626
GSM1296085Z_non-lesional_pre-dose17.5416