ProfileGDS5420 / 223001_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 91% 89% 90% 85% 90% 88% 86% 74% 92% 91% 92% 86% 90% 92% 91% 86% 80% 73% 80% 91% 85% 91% 92% 84% 87% 94% 89% 88% 93% 64% 88% 88% 85% 87% 90% 90% 89% 80% 87% 87% 89% 74% 84% 82% 82% 74% 84% 83% 83% 82% 84% 80% 76% 92% 84% 88% 85% 89% 91% 85% 77% 88% 81% 84% 82% 74% 77% 87% 73% 83% 88% 88% 87% 73% 87% 88% 76% 71% 86% 79% 83% 86% 72% 86% 87% 86% 77% 81% 85% 87% 84% 79% 76% 88% 82% 74% 85% 78% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose772.0475
GSM1296119B_lesional_pre-dose2279.2991
GSM1296076C_lesional_pre-dose2244.9889
GSM1296092D_lesional_pre-dose2309.2690
GSM1296103E_lesional_pre-dose1442.3785
GSM1296078F_lesional_pre-dose2317.3190
GSM1296107G_lesional_pre-dose1893.488
GSM1296109H_lesional_pre-dose1578.3386
GSM1296080I_lesional_pre-dose722.4774
GSM1296090J_lesional_pre-dose2657.1392
GSM1296074K_lesional_pre-dose2633.9691
GSM1296111L_lesional_pre-dose2420.3592
GSM1296099M_lesional_pre-dose1607.386
GSM1296086O_lesional_pre-dose2324.1390
GSM1296117P_lesional_pre-dose2525.7692
GSM1296113Q_lesional_pre-dose2173.9891
GSM1296096R_lesional_pre-dose1641.2186
GSM1296105S_lesional_pre-dose1049.2680
GSM1296098T_lesional_pre-dose692.4873
GSM1296101U_lesional_pre-dose1049.0680
GSM1296121V_lesional_pre-dose2437.4291
GSM1296088W_lesional_pre-dose1546.1685
GSM1296082X_lesional_pre-dose2561.6891
GSM1296115Y_lesional_pre-dose2457.4192
GSM1296084Z_lesional_pre-dose1354.4984
GSM1296072B_lesional_day81723.9987
GSM1296069L_lesional_day82795.3694
GSM1296071P_lesional_day81778.9689
GSM1296070Y_lesional_day81755.8888
GSM1296073V_lesional_day82901.2993
GSM1296034A_lesional_day15430.0164
GSM1296041G_lesional_day151895.0788
GSM1296035R_lesional_day151804.288
GSM1296038U_lesional_day151471.7585
GSM1296047B_lesional_day151592.4787
GSM1296039E_lesional_day152217.2890
GSM1296042H_lesional_day152004.4190
GSM1296043L_lesional_day151928.1989
GSM1296037M_lesional_day151050.980
GSM1296046P_lesional_day151656.387
GSM1296044Q_lesional_day151576.3687
GSM1296045Y_lesional_day151853.5689
GSM1296025C_lesional_day15744.6374
GSM1296033D_lesional_day151359.584
GSM1296027I_lesional_day151230.3382
GSM1296032J_lesional_day151172.4182
GSM1296024K_lesional_day15727.2174
GSM1296031W_lesional_day151332.1584
GSM1296028X_lesional_day151288.6483
GSM1296029Z_lesional_day151272.3383
GSM1296026F_lesional_day151229.6382
GSM1296030O_lesional_day151464.2984
GSM1296040S_lesional_day151058.2280
GSM1296036T_lesional_day15831.2176
GSM1296048V_lesional_day152461.5192
GSM1296059A_lesional_day431353.784
GSM1296066G_lesional_day431818.6388
GSM1296060R_lesional_day431501.4985
GSM1296063U_lesional_day432026.589
GSM1296064E_lesional_day432548.591
GSM1296067H_lesional_day431374.4485
GSM1296062M_lesional_day43903.2977
GSM1296068Q_lesional_day431635.9988
GSM1296050C_lesional_day431148.4281
GSM1296057D_lesional_day431408.3284
GSM1296052I_lesional_day431202.3182
GSM1296054J_lesional_day43755.8574
GSM1296049K_lesional_day43898.9677
GSM1296055W_lesional_day431700.5687
GSM1296053X_lesional_day43721.9673
GSM1296058Z_lesional_day431280.1283
GSM1296051F_lesional_day431901.4588
GSM1296056O_lesional_day431913.6588
GSM1296065S_lesional_day431670.4387
GSM1296061T_lesional_day43703.4673
GSM1296095A_non-lesional_pre-dose1802.4487
GSM1296120B_non-lesional_pre-dose1736.1588
GSM1296077C_non-lesional_pre-dose845.0776
GSM1296093D_non-lesional_pre-dose630.3871
GSM1296104E_non-lesional_pre-dose1589.7686
GSM1296079F_non-lesional_pre-dose996.379
GSM1296108G_non-lesional_pre-dose1308.7383
GSM1296110H_non-lesional_pre-dose1473.2986
GSM1296081I_non-lesional_pre-dose657.5772
GSM1296091J_non-lesional_pre-dose1679.386
GSM1296075K_non-lesional_pre-dose1771.3987
GSM1296112L_non-lesional_pre-dose1444.2186
GSM1296100M_non-lesional_pre-dose899.0977
GSM1296087O_non-lesional_pre-dose1191.7781
GSM1296118P_non-lesional_pre-dose1392.2585
GSM1296114Q_non-lesional_pre-dose1622.3287
GSM1296097R_non-lesional_pre-dose1365.1684
GSM1296106S_non-lesional_pre-dose1002.179
GSM1296102U_non-lesional_pre-dose809.0476
GSM1296122V_non-lesional_pre-dose1764.7688
GSM1296089W_non-lesional_pre-dose1160.1582
GSM1296083X_non-lesional_pre-dose752.1574
GSM1296116Y_non-lesional_pre-dose1389.0585
GSM1296085Z_non-lesional_pre-dose957.5178