ProfileGDS5420 / 222272_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 72% 59% 79% 58% 67% 77% 75% 69% 69% 59% 74% 63% 58% 60% 66% 65% 70% 59% 73% 57% 60% 65% 63% 60% 68% 60% 77% 67% 60% 64% 74% 63% 68% 66% 66% 70% 64% 64% 71% 66% 66% 62% 75% 62% 66% 68% 69% 71% 66% 65% 72% 62% 69% 67% 57% 67% 76% 74% 66% 63% 66% 65% 66% 80% 57% 65% 68% 81% 63% 71% 66% 77% 57% 68% 74% 70% 68% 79% 72% 68% 78% 66% 72% 73% 62% 76% 71% 69% 66% 72% 73% 69% 68% 67% 70% 72% 73% 69% 67% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose653.8772
GSM1296119B_lesional_pre-dose301.759
GSM1296076C_lesional_pre-dose993.3579
GSM1296092D_lesional_pre-dose260.858
GSM1296103E_lesional_pre-dose471.267
GSM1296078F_lesional_pre-dose887.3477
GSM1296107G_lesional_pre-dose784.1775
GSM1296109H_lesional_pre-dose550.4569
GSM1296080I_lesional_pre-dose527.9669
GSM1296090J_lesional_pre-dose275.7359
GSM1296074K_lesional_pre-dose736.1774
GSM1296111L_lesional_pre-dose372.5663
GSM1296099M_lesional_pre-dose294.4258
GSM1296086O_lesional_pre-dose302.3960
GSM1296117P_lesional_pre-dose452.9566
GSM1296113Q_lesional_pre-dose433.5265
GSM1296096R_lesional_pre-dose582.2570
GSM1296105S_lesional_pre-dose307.5359
GSM1296098T_lesional_pre-dose688.5473
GSM1296101U_lesional_pre-dose282.6157
GSM1296121V_lesional_pre-dose314.1560
GSM1296088W_lesional_pre-dose415.3465
GSM1296082X_lesional_pre-dose354.3463
GSM1296115Y_lesional_pre-dose313.3360
GSM1296084Z_lesional_pre-dose520.8368
GSM1296072B_lesional_day8318.2160
GSM1296069L_lesional_day8850.4577
GSM1296071P_lesional_day8487.7667
GSM1296070Y_lesional_day8330.0160
GSM1296073V_lesional_day8384.1964
GSM1296034A_lesional_day15749.7274
GSM1296041G_lesional_day15373.5863
GSM1296035R_lesional_day15525.1268
GSM1296038U_lesional_day15455.1466
GSM1296047B_lesional_day15466.6166
GSM1296039E_lesional_day15565.270
GSM1296042H_lesional_day15420.1564
GSM1296043L_lesional_day15425.9564
GSM1296037M_lesional_day15617.9871
GSM1296046P_lesional_day15459.766
GSM1296044Q_lesional_day15459.5666
GSM1296045Y_lesional_day15382.262
GSM1296025C_lesional_day15801.0375
GSM1296033D_lesional_day15352.9762
GSM1296027I_lesional_day15448.5666
GSM1296032J_lesional_day15535.6668
GSM1296024K_lesional_day15533.4369
GSM1296031W_lesional_day15631.1571
GSM1296028X_lesional_day15453.6566
GSM1296029Z_lesional_day15444.0665
GSM1296026F_lesional_day15654.0772
GSM1296030O_lesional_day15336.7562
GSM1296040S_lesional_day15548.0369
GSM1296036T_lesional_day15498.1867
GSM1296048V_lesional_day15261.3457
GSM1296059A_lesional_day43471.2967
GSM1296066G_lesional_day43802.0576
GSM1296060R_lesional_day43743.7774
GSM1296063U_lesional_day43449.2866
GSM1296064E_lesional_day43364.3663
GSM1296067H_lesional_day43485.8666
GSM1296062M_lesional_day43438.0765
GSM1296068Q_lesional_day43486.1466
GSM1296050C_lesional_day431067.280
GSM1296057D_lesional_day43267.4357
GSM1296052I_lesional_day43422.5965
GSM1296054J_lesional_day43541.0468
GSM1296049K_lesional_day431125.6581
GSM1296055W_lesional_day43395.0563
GSM1296053X_lesional_day43608.771
GSM1296058Z_lesional_day43443.8766
GSM1296051F_lesional_day43903.7577
GSM1296056O_lesional_day43254.7957
GSM1296065S_lesional_day43511.5268
GSM1296061T_lesional_day43731.4374
GSM1296095A_non-lesional_pre-dose570.5570
GSM1296120B_non-lesional_pre-dose512.1368
GSM1296077C_non-lesional_pre-dose1010.1979
GSM1296093D_non-lesional_pre-dose665.0672
GSM1296104E_non-lesional_pre-dose514.0168
GSM1296079F_non-lesional_pre-dose940.3578
GSM1296108G_non-lesional_pre-dose465.6966
GSM1296110H_non-lesional_pre-dose663.9572
GSM1296081I_non-lesional_pre-dose711.8473
GSM1296091J_non-lesional_pre-dose354.7862
GSM1296075K_non-lesional_pre-dose811.8476
GSM1296112L_non-lesional_pre-dose605.2471
GSM1296100M_non-lesional_pre-dose556.0169
GSM1296087O_non-lesional_pre-dose448.5566
GSM1296118P_non-lesional_pre-dose660.472
GSM1296114Q_non-lesional_pre-dose684.4873
GSM1296097R_non-lesional_pre-dose529.3269
GSM1296106S_non-lesional_pre-dose511.3868
GSM1296102U_non-lesional_pre-dose514.1267
GSM1296122V_non-lesional_pre-dose572.9770
GSM1296089W_non-lesional_pre-dose648.6972
GSM1296083X_non-lesional_pre-dose699.873
GSM1296116Y_non-lesional_pre-dose566.6569
GSM1296085Z_non-lesional_pre-dose498.4567