ProfileGDS5420 / 222248_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 33% 13% 19% 35% 20% 9% 14% 13% 21% 21% 18% 6% 16% 16% 0% 20% 25% 24% 21% 18% 24% 2% 13% 8% 29% 31% 14% 24% 21% 5% 23% 18% 37% 23% 24% 20% 8% 6% 17% 27% 29% 14% 33% 39% 13% 35% 31% 18% 33% 34% 2% 30% 26% 25% 24% 33% 20% 34% 27% 30% 16% 34% 19% 26% 37% 11% 32% 29% 7% 28% 40% 7% 30% 21% 26% 36% 29% 27% 32% 25% 19% 15% 24% 28% 32% 32% 20% 28% 18% 17% 24% 33% 27% 38% 25% 13% 20% 0% 22% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose57.0233
GSM1296119B_lesional_pre-dose16.8813
GSM1296076C_lesional_pre-dose24.6519
GSM1296092D_lesional_pre-dose57.135
GSM1296103E_lesional_pre-dose22.0620
GSM1296078F_lesional_pre-dose9.759
GSM1296107G_lesional_pre-dose17.6314
GSM1296109H_lesional_pre-dose16.2813
GSM1296080I_lesional_pre-dose22.921
GSM1296090J_lesional_pre-dose22.9821
GSM1296074K_lesional_pre-dose18.2618
GSM1296111L_lesional_pre-dose7.956
GSM1296099M_lesional_pre-dose16.9916
GSM1296086O_lesional_pre-dose16.1916
GSM1296117P_lesional_pre-dose0.20
GSM1296113Q_lesional_pre-dose33.4420
GSM1296096R_lesional_pre-dose30.6425
GSM1296105S_lesional_pre-dose32.4924
GSM1296098T_lesional_pre-dose31.4621
GSM1296101U_lesional_pre-dose19.5918
GSM1296121V_lesional_pre-dose34.3324
GSM1296088W_lesional_pre-dose1.92
GSM1296082X_lesional_pre-dose11.8913
GSM1296115Y_lesional_pre-dose8.958
GSM1296084Z_lesional_pre-dose44.9429
GSM1296072B_lesional_day858.2131
GSM1296069L_lesional_day819.0114
GSM1296071P_lesional_day841.3124
GSM1296070Y_lesional_day831.5621
GSM1296073V_lesional_day85.675
GSM1296034A_lesional_day1531.0523
GSM1296041G_lesional_day1524.6918
GSM1296035R_lesional_day1567.8237
GSM1296038U_lesional_day1528.5123
GSM1296047B_lesional_day1539.7524
GSM1296039E_lesional_day1524.8820
GSM1296042H_lesional_day1510.838
GSM1296043L_lesional_day158.316
GSM1296037M_lesional_day1520.4817
GSM1296046P_lesional_day1548.2727
GSM1296044Q_lesional_day1553.129
GSM1296045Y_lesional_day1520.6114
GSM1296025C_lesional_day1556.5533
GSM1296033D_lesional_day1581.5439
GSM1296027I_lesional_day1510.9313
GSM1296032J_lesional_day1564.1135
GSM1296024K_lesional_day1547.6131
GSM1296031W_lesional_day1521.6218
GSM1296028X_lesional_day1555.3133
GSM1296029Z_lesional_day1559.3334
GSM1296026F_lesional_day151.862
GSM1296030O_lesional_day1537.1830
GSM1296040S_lesional_day1537.3626
GSM1296036T_lesional_day1535.8125
GSM1296048V_lesional_day1535.9824
GSM1296059A_lesional_day4351.8333
GSM1296066G_lesional_day4329.1820
GSM1296060R_lesional_day4359.6134
GSM1296063U_lesional_day4339.3727
GSM1296064E_lesional_day4344.8430
GSM1296067H_lesional_day4320.8816
GSM1296062M_lesional_day4360.7934
GSM1296068Q_lesional_day4331.5819
GSM1296050C_lesional_day4337.7826
GSM1296057D_lesional_day4372.3737
GSM1296052I_lesional_day4310.3911
GSM1296054J_lesional_day4355.0932
GSM1296049K_lesional_day4345.3629
GSM1296055W_lesional_day437.597
GSM1296053X_lesional_day4340.0128
GSM1296058Z_lesional_day4382.9440
GSM1296051F_lesional_day437.17
GSM1296056O_lesional_day4340.5630
GSM1296065S_lesional_day4325.5321
GSM1296061T_lesional_day4337.7326
GSM1296095A_non-lesional_pre-dose6736
GSM1296120B_non-lesional_pre-dose52.8929
GSM1296077C_non-lesional_pre-dose36.927
GSM1296093D_non-lesional_pre-dose55.8232
GSM1296104E_non-lesional_pre-dose36.0425
GSM1296079F_non-lesional_pre-dose23.8319
GSM1296108G_non-lesional_pre-dose17.915
GSM1296110H_non-lesional_pre-dose39.1124
GSM1296081I_non-lesional_pre-dose35.7528
GSM1296091J_non-lesional_pre-dose50.0732
GSM1296075K_non-lesional_pre-dose53.4332
GSM1296112L_non-lesional_pre-dose34.8320
GSM1296100M_non-lesional_pre-dose42.0128
GSM1296087O_non-lesional_pre-dose17.9718
GSM1296118P_non-lesional_pre-dose25.7917
GSM1296114Q_non-lesional_pre-dose39.1524
GSM1296097R_non-lesional_pre-dose55.4533
GSM1296106S_non-lesional_pre-dose42.9827
GSM1296102U_non-lesional_pre-dose88.2938
GSM1296122V_non-lesional_pre-dose40.2225
GSM1296089W_non-lesional_pre-dose14.5713
GSM1296083X_non-lesional_pre-dose22.6320
GSM1296116Y_non-lesional_pre-dose0.120
GSM1296085Z_non-lesional_pre-dose27.7522