ProfileGDS5420 / 222106_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 28% 33% 34% 41% 19% 41% 26% 47% 27% 66% 60% 47% 37% 30% 50% 18% 37% 46% 33% 35% 46% 43% 27% 15% 41% 50% 42% 66% 43% 29% 51% 64% 34% 31% 55% 40% 61% 59% 55% 60% 24% 52% 46% 58% 49% 69% 80% 42% 41% 76% 75% 45% 52% 60% 58% 43% 48% 58% 41% 55% 85% 31% 48% 69% 58% 59% 77% 80% 77% 50% 68% 84% 43% 47% 83% 15% 40% 36% 16% 17% 47% 27% 52% 6% 50% 49% 26% 34% 58% 46% 17% 43% 44% 53% 60% 47% 41% 20% 56% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose39.8528
GSM1296119B_lesional_pre-dose67.1533
GSM1296076C_lesional_pre-dose59.2434
GSM1296092D_lesional_pre-dose83.9541
GSM1296103E_lesional_pre-dose20.9919
GSM1296078F_lesional_pre-dose89.3941
GSM1296107G_lesional_pre-dose43.5226
GSM1296109H_lesional_pre-dose156.0847
GSM1296080I_lesional_pre-dose34.6827
GSM1296090J_lesional_pre-dose437.1966
GSM1296074K_lesional_pre-dose276.3360
GSM1296111L_lesional_pre-dose159.4347
GSM1296099M_lesional_pre-dose73.4537
GSM1296086O_lesional_pre-dose45.0930
GSM1296117P_lesional_pre-dose181.8550
GSM1296113Q_lesional_pre-dose30.6718
GSM1296096R_lesional_pre-dose69.7737
GSM1296105S_lesional_pre-dose138.9246
GSM1296098T_lesional_pre-dose65.9933
GSM1296101U_lesional_pre-dose68.135
GSM1296121V_lesional_pre-dose140.1346
GSM1296088W_lesional_pre-dose103.7743
GSM1296082X_lesional_pre-dose34.5427
GSM1296115Y_lesional_pre-dose17.6815
GSM1296084Z_lesional_pre-dose100.1741
GSM1296072B_lesional_day8187.8750
GSM1296069L_lesional_day8125.9742
GSM1296071P_lesional_day8483.0966
GSM1296070Y_lesional_day8129.343
GSM1296073V_lesional_day847.7829
GSM1296034A_lesional_day15194.0251
GSM1296041G_lesional_day15409.9664
GSM1296035R_lesional_day1557.334
GSM1296038U_lesional_day1549.9731
GSM1296047B_lesional_day15252.655
GSM1296039E_lesional_day1587.740
GSM1296042H_lesional_day15343.7761
GSM1296043L_lesional_day15319.5359
GSM1296037M_lesional_day15241.8655
GSM1296046P_lesional_day15332.0360
GSM1296044Q_lesional_day1538.424
GSM1296045Y_lesional_day15214.7452
GSM1296025C_lesional_day15133.0346
GSM1296033D_lesional_day1528358
GSM1296027I_lesional_day15145.6149
GSM1296032J_lesional_day15562.769
GSM1296024K_lesional_day151071.6680
GSM1296031W_lesional_day15107.7642
GSM1296028X_lesional_day1595.4641
GSM1296029Z_lesional_day15857.0476
GSM1296026F_lesional_day15791.275
GSM1296030O_lesional_day15106.6345
GSM1296040S_lesional_day15204.7552
GSM1296036T_lesional_day15336.1260
GSM1296048V_lesional_day15284.8658
GSM1296059A_lesional_day43104.6343
GSM1296066G_lesional_day43167.0448
GSM1296060R_lesional_day43293.0758
GSM1296063U_lesional_day43100.941
GSM1296064E_lesional_day43220.1555
GSM1296067H_lesional_day431434.2285
GSM1296062M_lesional_day435031
GSM1296068Q_lesional_day43175.0348
GSM1296050C_lesional_day43532.2169
GSM1296057D_lesional_day43294.4858
GSM1296052I_lesional_day43289.2559
GSM1296054J_lesional_day43873.5477
GSM1296049K_lesional_day431041.6580
GSM1296055W_lesional_day43881.7677
GSM1296053X_lesional_day43176.0150
GSM1296058Z_lesional_day43525.4168
GSM1296051F_lesional_day431404.7884
GSM1296056O_lesional_day43104.2143
GSM1296065S_lesional_day43151.0747
GSM1296061T_lesional_day431271.7383
GSM1296095A_non-lesional_pre-dose15.5815
GSM1296120B_non-lesional_pre-dose103.440
GSM1296077C_non-lesional_pre-dose68.1336
GSM1296093D_non-lesional_pre-dose18.8916
GSM1296104E_non-lesional_pre-dose21.1617
GSM1296079F_non-lesional_pre-dose139.6247
GSM1296108G_non-lesional_pre-dose44.2227
GSM1296110H_non-lesional_pre-dose220.9952
GSM1296081I_non-lesional_pre-dose4.766
GSM1296091J_non-lesional_pre-dose160.8950
GSM1296075K_non-lesional_pre-dose150.1949
GSM1296112L_non-lesional_pre-dose48.3326
GSM1296100M_non-lesional_pre-dose64.6834
GSM1296087O_non-lesional_pre-dose257.1458
GSM1296118P_non-lesional_pre-dose153.746
GSM1296114Q_non-lesional_pre-dose25.2417
GSM1296097R_non-lesional_pre-dose108.6243
GSM1296106S_non-lesional_pre-dose131.1144
GSM1296102U_non-lesional_pre-dose227.5553
GSM1296122V_non-lesional_pre-dose327.7460
GSM1296089W_non-lesional_pre-dose149.0947
GSM1296083X_non-lesional_pre-dose94.3441
GSM1296116Y_non-lesional_pre-dose34.0120
GSM1296085Z_non-lesional_pre-dose253.2256