ProfileGDS5420 / 221006_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 44% 47% 44% 40% 53% 43% 48% 48% 39% 45% 43% 50% 37% 42% 50% 61% 44% 44% 53% 48% 50% 40% 42% 53% 45% 44% 51% 52% 51% 49% 49% 51% 46% 46% 51% 46% 48% 52% 41% 55% 54% 55% 47% 38% 39% 43% 47% 41% 36% 41% 40% 42% 46% 50% 48% 49% 53% 46% 50% 47% 44% 47% 55% 47% 45% 38% 52% 42% 41% 42% 40% 41% 41% 43% 54% 49% 48% 46% 47% 44% 40% 51% 51% 31% 42% 50% 51% 48% 40% 54% 61% 42% 41% 49% 44% 53% 29% 56% 42% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose116.1344
GSM1296119B_lesional_pre-dose149.847
GSM1296076C_lesional_pre-dose112.9544
GSM1296092D_lesional_pre-dose79.5540
GSM1296103E_lesional_pre-dose205.2453
GSM1296078F_lesional_pre-dose99.343
GSM1296107G_lesional_pre-dose166.948
GSM1296109H_lesional_pre-dose165.5448
GSM1296080I_lesional_pre-dose76.7339
GSM1296090J_lesional_pre-dose116.9645
GSM1296074K_lesional_pre-dose95.843
GSM1296111L_lesional_pre-dose183.0450
GSM1296099M_lesional_pre-dose77.8137
GSM1296086O_lesional_pre-dose95.7842
GSM1296117P_lesional_pre-dose189.2150
GSM1296113Q_lesional_pre-dose353.7461
GSM1296096R_lesional_pre-dose117.7244
GSM1296105S_lesional_pre-dose125.6444
GSM1296098T_lesional_pre-dose206.3753
GSM1296101U_lesional_pre-dose158.7648
GSM1296121V_lesional_pre-dose174.9950
GSM1296088W_lesional_pre-dose85.0440
GSM1296082X_lesional_pre-dose92.0142
GSM1296115Y_lesional_pre-dose217.6753
GSM1296084Z_lesional_pre-dose126.4645
GSM1296072B_lesional_day8129.7844
GSM1296069L_lesional_day8210.5751
GSM1296071P_lesional_day8216.5552
GSM1296070Y_lesional_day8206.651
GSM1296073V_lesional_day8160.6749
GSM1296034A_lesional_day15174.8149
GSM1296041G_lesional_day15187.1951
GSM1296035R_lesional_day15127.0146
GSM1296038U_lesional_day15131.0246
GSM1296047B_lesional_day15194.3851
GSM1296039E_lesional_day1513046
GSM1296042H_lesional_day15170.1448
GSM1296043L_lesional_day15213.7852
GSM1296037M_lesional_day15106.5141
GSM1296046P_lesional_day15254.855
GSM1296044Q_lesional_day15247.1654
GSM1296045Y_lesional_day15255.455
GSM1296025C_lesional_day15138.9947
GSM1296033D_lesional_day1578.4838
GSM1296027I_lesional_day1571.6439
GSM1296032J_lesional_day15108.4143
GSM1296024K_lesional_day15132.5847
GSM1296031W_lesional_day15106.6741
GSM1296028X_lesional_day1566.236
GSM1296029Z_lesional_day1593.4241
GSM1296026F_lesional_day1586.4940
GSM1296030O_lesional_day1589.2742
GSM1296040S_lesional_day15143.0946
GSM1296036T_lesional_day15190.4650
GSM1296048V_lesional_day15157.6348
GSM1296059A_lesional_day43152.6149
GSM1296066G_lesional_day43223.653
GSM1296060R_lesional_day43130.7546
GSM1296063U_lesional_day43177.5950
GSM1296064E_lesional_day43136.5947
GSM1296067H_lesional_day43139.6744
GSM1296062M_lesional_day43142.8447
GSM1296068Q_lesional_day43261.5955
GSM1296050C_lesional_day43140.6947
GSM1296057D_lesional_day43126.6945
GSM1296052I_lesional_day4371.8738
GSM1296054J_lesional_day43203.4852
GSM1296049K_lesional_day43101.6342
GSM1296055W_lesional_day43104.1241
GSM1296053X_lesional_day43103.642
GSM1296058Z_lesional_day4383.9440
GSM1296051F_lesional_day4394.4641
GSM1296056O_lesional_day4388.8241
GSM1296065S_lesional_day43111.5943
GSM1296061T_lesional_day43227.2754
GSM1296095A_non-lesional_pre-dose156.949
GSM1296120B_non-lesional_pre-dose169.7748
GSM1296077C_non-lesional_pre-dose127.4146
GSM1296093D_non-lesional_pre-dose152.2247
GSM1296104E_non-lesional_pre-dose118.344
GSM1296079F_non-lesional_pre-dose88.9640
GSM1296108G_non-lesional_pre-dose201.1351
GSM1296110H_non-lesional_pre-dose203.251
GSM1296081I_non-lesional_pre-dose42.2331
GSM1296091J_non-lesional_pre-dose98.9242
GSM1296075K_non-lesional_pre-dose160.2850
GSM1296112L_non-lesional_pre-dose217.151
GSM1296100M_non-lesional_pre-dose157.1248
GSM1296087O_non-lesional_pre-dose79.8840
GSM1296118P_non-lesional_pre-dose245.4254
GSM1296114Q_non-lesional_pre-dose355.361
GSM1296097R_non-lesional_pre-dose103.8642
GSM1296106S_non-lesional_pre-dose110.3541
GSM1296102U_non-lesional_pre-dose171.6249
GSM1296122V_non-lesional_pre-dose134.9544
GSM1296089W_non-lesional_pre-dose225.8753
GSM1296083X_non-lesional_pre-dose41.4729
GSM1296116Y_non-lesional_pre-dose267.8756
GSM1296085Z_non-lesional_pre-dose101.6542