ProfileGDS5420 / 220765_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 36% 46% 33% 41% 43% 48% 52% 55% 43% 40% 43% 51% 35% 46% 53% 48% 60% 49% 48% 39% 39% 34% 44% 49% 39% 48% 53% 47% 39% 66% 41% 48% 52% 48% 39% 49% 54% 69% 40% 51% 50% 66% 48% 63% 56% 62% 57% 56% 60% 54% 52% 63% 44% 39% 54% 47% 49% 46% 38% 56% 57% 52% 57% 55% 60% 57% 56% 62% 61% 65% 47% 48% 49% 56% 48% 42% 62% 55% 49% 59% 51% 51% 66% 48% 53% 56% 70% 60% 48% 53% 57% 54% 61% 58% 57% 65% 46% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose148.4848
GSM1296119B_lesional_pre-dose8036
GSM1296076C_lesional_pre-dose121.4146
GSM1296092D_lesional_pre-dose48.6133
GSM1296103E_lesional_pre-dose93.9941
GSM1296078F_lesional_pre-dose103.6143
GSM1296107G_lesional_pre-dose159.8548
GSM1296109H_lesional_pre-dose205.8952
GSM1296080I_lesional_pre-dose230.1255
GSM1296090J_lesional_pre-dose99.3743
GSM1296074K_lesional_pre-dose77.2240
GSM1296111L_lesional_pre-dose127.3343
GSM1296099M_lesional_pre-dose189.7151
GSM1296086O_lesional_pre-dose61.8335
GSM1296117P_lesional_pre-dose149.9546
GSM1296113Q_lesional_pre-dose231.1453
GSM1296096R_lesional_pre-dose147.5948
GSM1296105S_lesional_pre-dose329.3260
GSM1296098T_lesional_pre-dose170.4649
GSM1296101U_lesional_pre-dose156.8348
GSM1296121V_lesional_pre-dose90.7939
GSM1296088W_lesional_pre-dose81.1239
GSM1296082X_lesional_pre-dose55.4234
GSM1296115Y_lesional_pre-dose123.7744
GSM1296084Z_lesional_pre-dose161.4449
GSM1296072B_lesional_day895.2639
GSM1296069L_lesional_day8174.5948
GSM1296071P_lesional_day8232.0953
GSM1296070Y_lesional_day8159.947
GSM1296073V_lesional_day890.6939
GSM1296034A_lesional_day15490.7666
GSM1296041G_lesional_day15105.5241
GSM1296035R_lesional_day15144.7248
GSM1296038U_lesional_day15189.6852
GSM1296047B_lesional_day15163.8348
GSM1296039E_lesional_day1583.8639
GSM1296042H_lesional_day15177.3149
GSM1296043L_lesional_day15246.8854
GSM1296037M_lesional_day15548.4669
GSM1296046P_lesional_day15108.9340
GSM1296044Q_lesional_day15205.6951
GSM1296045Y_lesional_day15194.1750
GSM1296025C_lesional_day15445.3266
GSM1296033D_lesional_day15149.4148
GSM1296027I_lesional_day15364.1763
GSM1296032J_lesional_day15258.1756
GSM1296024K_lesional_day15356.1162
GSM1296031W_lesional_day15283.4657
GSM1296028X_lesional_day15243.7456
GSM1296029Z_lesional_day15325.5560
GSM1296026F_lesional_day15209.1554
GSM1296030O_lesional_day15174.5352
GSM1296040S_lesional_day15382.163
GSM1296036T_lesional_day15126.2244
GSM1296048V_lesional_day1592.8339
GSM1296059A_lesional_day43214.4854
GSM1296066G_lesional_day43156.3247
GSM1296060R_lesional_day43162.1449
GSM1296063U_lesional_day43139.0846
GSM1296064E_lesional_day4375.1738
GSM1296067H_lesional_day43279.0756
GSM1296062M_lesional_day43268.7657
GSM1296068Q_lesional_day43217.4752
GSM1296050C_lesional_day43264.5157
GSM1296057D_lesional_day43242.4855
GSM1296052I_lesional_day43293.8360
GSM1296054J_lesional_day43273.8857
GSM1296049K_lesional_day43250.5556
GSM1296055W_lesional_day43372.6862
GSM1296053X_lesional_day43349.961
GSM1296058Z_lesional_day43422.165
GSM1296051F_lesional_day43135.4447
GSM1296056O_lesional_day43137.2148
GSM1296065S_lesional_day43168.3749
GSM1296061T_lesional_day43254.2556
GSM1296095A_non-lesional_pre-dose14448
GSM1296120B_non-lesional_pre-dose114.4842
GSM1296077C_non-lesional_pre-dose340.2262
GSM1296093D_non-lesional_pre-dose243.3255
GSM1296104E_non-lesional_pre-dose158.9349
GSM1296079F_non-lesional_pre-dose291.9259
GSM1296108G_non-lesional_pre-dose199.8151
GSM1296110H_non-lesional_pre-dose212.7951
GSM1296081I_non-lesional_pre-dose435.8566
GSM1296091J_non-lesional_pre-dose142.0848
GSM1296075K_non-lesional_pre-dose195.2153
GSM1296112L_non-lesional_pre-dose277.556
GSM1296100M_non-lesional_pre-dose602.4370
GSM1296087O_non-lesional_pre-dose299.2160
GSM1296118P_non-lesional_pre-dose169.1948
GSM1296114Q_non-lesional_pre-dose228.553
GSM1296097R_non-lesional_pre-dose261.8257
GSM1296106S_non-lesional_pre-dose232.2754
GSM1296102U_non-lesional_pre-dose360.8461
GSM1296122V_non-lesional_pre-dose292.7658
GSM1296089W_non-lesional_pre-dose282.8257
GSM1296083X_non-lesional_pre-dose450.165
GSM1296116Y_non-lesional_pre-dose159.746
GSM1296085Z_non-lesional_pre-dose323.6660