ProfileGDS5420 / 220261_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 56% 70% 74% 76% 62% 73% 70% 62% 53% 78% 77% 74% 71% 74% 71% 68% 73% 65% 51% 60% 75% 67% 76% 73% 67% 71% 73% 69% 72% 74% 48% 69% 75% 72% 69% 72% 70% 72% 72% 69% 71% 75% 56% 71% 69% 74% 53% 74% 69% 68% 60% 71% 64% 55% 74% 71% 71% 69% 77% 77% 63% 58% 72% 75% 75% 69% 64% 57% 78% 64% 74% 73% 78% 76% 53% 75% 71% 65% 58% 73% 65% 70% 61% 67% 75% 72% 68% 71% 77% 68% 70% 72% 67% 66% 72% 71% 63% 66% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose257.4356
GSM1296119B_lesional_pre-dose577.7770
GSM1296076C_lesional_pre-dose696.2974
GSM1296092D_lesional_pre-dose829.4876
GSM1296103E_lesional_pre-dose365.6962
GSM1296078F_lesional_pre-dose647.7873
GSM1296107G_lesional_pre-dose578.7970
GSM1296109H_lesional_pre-dose372.5462
GSM1296080I_lesional_pre-dose192.1853
GSM1296090J_lesional_pre-dose958.8578
GSM1296074K_lesional_pre-dose858.7477
GSM1296111L_lesional_pre-dose729.4674
GSM1296099M_lesional_pre-dose640.9171
GSM1296086O_lesional_pre-dose719.0474
GSM1296117P_lesional_pre-dose611.8371
GSM1296113Q_lesional_pre-dose512.7968
GSM1296096R_lesional_pre-dose712.2873
GSM1296105S_lesional_pre-dose434.7865
GSM1296098T_lesional_pre-dose185.0651
GSM1296101U_lesional_pre-dose332.0560
GSM1296121V_lesional_pre-dose748.0875
GSM1296088W_lesional_pre-dose473.2467
GSM1296082X_lesional_pre-dose819.7876
GSM1296115Y_lesional_pre-dose678.9473
GSM1296084Z_lesional_pre-dose477.867
GSM1296072B_lesional_day8611.171
GSM1296069L_lesional_day8693.0773
GSM1296071P_lesional_day8545.4869
GSM1296070Y_lesional_day8657.2472
GSM1296073V_lesional_day8735.3374
GSM1296034A_lesional_day15162.0948
GSM1296041G_lesional_day15545.2369
GSM1296035R_lesional_day15767.6775
GSM1296038U_lesional_day15656.372
GSM1296047B_lesional_day15548.5169
GSM1296039E_lesional_day15643.7672
GSM1296042H_lesional_day15580.7770
GSM1296043L_lesional_day15642.7572
GSM1296037M_lesional_day15642.9272
GSM1296046P_lesional_day15563.2369
GSM1296044Q_lesional_day15619.0971
GSM1296045Y_lesional_day15745.1175
GSM1296025C_lesional_day15234.7156
GSM1296033D_lesional_day15622.7871
GSM1296027I_lesional_day15543.8369
GSM1296032J_lesional_day15726.4174
GSM1296024K_lesional_day15204.3853
GSM1296031W_lesional_day15730.0674
GSM1296028X_lesional_day15540.7869
GSM1296029Z_lesional_day15517.4668
GSM1296026F_lesional_day15309.9160
GSM1296030O_lesional_day15625.8471
GSM1296040S_lesional_day15419.964
GSM1296036T_lesional_day15252.6355
GSM1296048V_lesional_day15699.5974
GSM1296059A_lesional_day43595.1271
GSM1296066G_lesional_day43592.8671
GSM1296060R_lesional_day43554.7269
GSM1296063U_lesional_day43886.6177
GSM1296064E_lesional_day43884.277
GSM1296067H_lesional_day43413.9563
GSM1296062M_lesional_day43287.2558
GSM1296068Q_lesional_day43648.8372
GSM1296050C_lesional_day43758.9275
GSM1296057D_lesional_day43797.2175
GSM1296052I_lesional_day43518.4569
GSM1296054J_lesional_day43407.2264
GSM1296049K_lesional_day43268.4757
GSM1296055W_lesional_day43925.4778
GSM1296053X_lesional_day43416.7964
GSM1296058Z_lesional_day43754.8374
GSM1296051F_lesional_day43659.8173
GSM1296056O_lesional_day43935.378
GSM1296065S_lesional_day43811.9176
GSM1296061T_lesional_day43211.5853
GSM1296095A_non-lesional_pre-dose757.2575
GSM1296120B_non-lesional_pre-dose614.871
GSM1296077C_non-lesional_pre-dose427.8265
GSM1296093D_non-lesional_pre-dose303.9658
GSM1296104E_non-lesional_pre-dose680.0273
GSM1296079F_non-lesional_pre-dose401.865
GSM1296108G_non-lesional_pre-dose563.2970
GSM1296110H_non-lesional_pre-dose353.4561
GSM1296081I_non-lesional_pre-dose480.9467
GSM1296091J_non-lesional_pre-dose804.7675
GSM1296075K_non-lesional_pre-dose651.1572
GSM1296112L_non-lesional_pre-dose533.668
GSM1296100M_non-lesional_pre-dose613.1871
GSM1296087O_non-lesional_pre-dose913.7477
GSM1296118P_non-lesional_pre-dose536.7868
GSM1296114Q_non-lesional_pre-dose577.0470
GSM1296097R_non-lesional_pre-dose649.3572
GSM1296106S_non-lesional_pre-dose497.7267
GSM1296102U_non-lesional_pre-dose475.6566
GSM1296122V_non-lesional_pre-dose634.0272
GSM1296089W_non-lesional_pre-dose638.1171
GSM1296083X_non-lesional_pre-dose379.6763
GSM1296116Y_non-lesional_pre-dose463.1366
GSM1296085Z_non-lesional_pre-dose546.1969