ProfileGDS5420 / 219641_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 45% 48% 54% 45% 39% 51% 47% 33% 50% 52% 49% 52% 45% 47% 49% 51% 43% 42% 54% 50% 54% 40% 48% 46% 54% 55% 49% 53% 55% 51% 48% 50% 48% 54% 56% 50% 52% 55% 46% 51% 46% 56% 53% 48% 50% 49% 51% 46% 48% 47% 49% 49% 37% 53% 56% 49% 48% 57% 50% 53% 48% 53% 55% 58% 52% 54% 51% 53% 45% 58% 51% 58% 49% 45% 57% 54% 57% 54% 58% 50% 49% 51% 47% 50% 58% 53% 48% 52% 54% 52% 54% 46% 53% 51% 46% 55% 51% 53% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose15348
GSM1296119B_lesional_pre-dose134.6645
GSM1296076C_lesional_pre-dose139.5248
GSM1296092D_lesional_pre-dose201.4154
GSM1296103E_lesional_pre-dose119.645
GSM1296078F_lesional_pre-dose80.8139
GSM1296107G_lesional_pre-dose197.0251
GSM1296109H_lesional_pre-dose152.2647
GSM1296080I_lesional_pre-dose5133
GSM1296090J_lesional_pre-dose157.9750
GSM1296074K_lesional_pre-dose174.652
GSM1296111L_lesional_pre-dose170.3649
GSM1296099M_lesional_pre-dose205.0552
GSM1296086O_lesional_pre-dose114.0545
GSM1296117P_lesional_pre-dose153.3647
GSM1296113Q_lesional_pre-dose186.6349
GSM1296096R_lesional_pre-dose175.751
GSM1296105S_lesional_pre-dose115.3943
GSM1296098T_lesional_pre-dose107.7242
GSM1296101U_lesional_pre-dose225.0754
GSM1296121V_lesional_pre-dose177.1750
GSM1296088W_lesional_pre-dose207.8454
GSM1296082X_lesional_pre-dose81.5340
GSM1296115Y_lesional_pre-dose155.4248
GSM1296084Z_lesional_pre-dose133.1546
GSM1296072B_lesional_day8234.8154
GSM1296069L_lesional_day8255.6755
GSM1296071P_lesional_day8192.1349
GSM1296070Y_lesional_day8227.2253
GSM1296073V_lesional_day8224.9155
GSM1296034A_lesional_day15195.2151
GSM1296041G_lesional_day15164.1148
GSM1296035R_lesional_day15169.8850
GSM1296038U_lesional_day15151.0648
GSM1296047B_lesional_day15233.7954
GSM1296039E_lesional_day15238.0856
GSM1296042H_lesional_day15186.9850
GSM1296043L_lesional_day15218.0752
GSM1296037M_lesional_day15249.5555
GSM1296046P_lesional_day15155.9746
GSM1296044Q_lesional_day15202.7551
GSM1296045Y_lesional_day15156.9846
GSM1296025C_lesional_day15241.1356
GSM1296033D_lesional_day15212.2953
GSM1296027I_lesional_day15130.1948
GSM1296032J_lesional_day15175.2550
GSM1296024K_lesional_day15155.4649
GSM1296031W_lesional_day15195.2651
GSM1296028X_lesional_day15127.9446
GSM1296029Z_lesional_day15151.448
GSM1296026F_lesional_day15136.0747
GSM1296030O_lesional_day15137.2849
GSM1296040S_lesional_day15162.6549
GSM1296036T_lesional_day1583.7537
GSM1296048V_lesional_day15213.8353
GSM1296059A_lesional_day43244.2656
GSM1296066G_lesional_day43172.5549
GSM1296060R_lesional_day43153.2948
GSM1296063U_lesional_day43261.7157
GSM1296064E_lesional_day43163.8650
GSM1296067H_lesional_day43227.8953
GSM1296062M_lesional_day43155.8748
GSM1296068Q_lesional_day43233.6353
GSM1296050C_lesional_day43232.5555
GSM1296057D_lesional_day43280.3158
GSM1296052I_lesional_day43186.8252
GSM1296054J_lesional_day43238.9254
GSM1296049K_lesional_day43183.851
GSM1296055W_lesional_day43216.2153
GSM1296053X_lesional_day43123.4145
GSM1296058Z_lesional_day43287.6158
GSM1296051F_lesional_day43177.1851
GSM1296056O_lesional_day43275.5458
GSM1296065S_lesional_day43169.3449
GSM1296061T_lesional_day43127.5345
GSM1296095A_non-lesional_pre-dose266.7757
GSM1296120B_non-lesional_pre-dose234.3354
GSM1296077C_non-lesional_pre-dose259.3157
GSM1296093D_non-lesional_pre-dose232.6354
GSM1296104E_non-lesional_pre-dose282.1758
GSM1296079F_non-lesional_pre-dose161.8750
GSM1296108G_non-lesional_pre-dose171.2349
GSM1296110H_non-lesional_pre-dose209.0851
GSM1296081I_non-lesional_pre-dose127.2447
GSM1296091J_non-lesional_pre-dose161.7450
GSM1296075K_non-lesional_pre-dose257.7758
GSM1296112L_non-lesional_pre-dose237.8953
GSM1296100M_non-lesional_pre-dose163.6648
GSM1296087O_non-lesional_pre-dose171.4252
GSM1296118P_non-lesional_pre-dose244.954
GSM1296114Q_non-lesional_pre-dose215.9952
GSM1296097R_non-lesional_pre-dose219.7754
GSM1296106S_non-lesional_pre-dose147.8246
GSM1296102U_non-lesional_pre-dose220.6753
GSM1296122V_non-lesional_pre-dose202.0451
GSM1296089W_non-lesional_pre-dose145.646
GSM1296083X_non-lesional_pre-dose242.5355
GSM1296116Y_non-lesional_pre-dose210.2451
GSM1296085Z_non-lesional_pre-dose203.5653