ProfileGDS5420 / 218605_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 80% 91% 89% 87% 86% 89% 88% 88% 79% 87% 87% 90% 90% 88% 89% 85% 90% 81% 76% 81% 91% 86% 89% 91% 82% 89% 88% 87% 89% 91% 74% 90% 86% 86% 88% 86% 89% 85% 80% 85% 85% 88% 85% 84% 83% 81% 77% 81% 80% 77% 84% 83% 84% 79% 91% 86% 88% 88% 89% 90% 89% 84% 84% 84% 84% 80% 78% 80% 83% 78% 81% 86% 89% 88% 76% 86% 86% 80% 75% 83% 82% 85% 86% 70% 82% 84% 85% 78% 84% 86% 82% 83% 82% 81% 85% 79% 70% 87% 80% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1061.6480
GSM1296119B_lesional_pre-dose2281.5491
GSM1296076C_lesional_pre-dose2076.9589
GSM1296092D_lesional_pre-dose1749.7687
GSM1296103E_lesional_pre-dose1589.7286
GSM1296078F_lesional_pre-dose2093.5289
GSM1296107G_lesional_pre-dose1790.8988
GSM1296109H_lesional_pre-dose1735.5488
GSM1296080I_lesional_pre-dose1015.3679
GSM1296090J_lesional_pre-dose1785.3287
GSM1296074K_lesional_pre-dose1906.1487
GSM1296111L_lesional_pre-dose2050.9390
GSM1296099M_lesional_pre-dose2121.290
GSM1296086O_lesional_pre-dose1914.6188
GSM1296117P_lesional_pre-dose1937.1189
GSM1296113Q_lesional_pre-dose1375.9485
GSM1296096R_lesional_pre-dose2099.7590
GSM1296105S_lesional_pre-dose1102.0481
GSM1296098T_lesional_pre-dose826.3176
GSM1296101U_lesional_pre-dose1104.9981
GSM1296121V_lesional_pre-dose2447.7291
GSM1296088W_lesional_pre-dose1638.1186
GSM1296082X_lesional_pre-dose2215.2889
GSM1296115Y_lesional_pre-dose2337.591
GSM1296084Z_lesional_pre-dose1236.8382
GSM1296072B_lesional_day81984.2189
GSM1296069L_lesional_day81793.5988
GSM1296071P_lesional_day81571.8887
GSM1296070Y_lesional_day81848.6389
GSM1296073V_lesional_day82456.5591
GSM1296034A_lesional_day15757.9374
GSM1296041G_lesional_day152122.6890
GSM1296035R_lesional_day151565.7886
GSM1296038U_lesional_day151648.8286
GSM1296047B_lesional_day151768.6788
GSM1296039E_lesional_day151672.8186
GSM1296042H_lesional_day151957.9789
GSM1296043L_lesional_day151442.8585
GSM1296037M_lesional_day151050.2480
GSM1296046P_lesional_day151380.1185
GSM1296044Q_lesional_day151419.385
GSM1296045Y_lesional_day151680.5288
GSM1296025C_lesional_day151486.4585
GSM1296033D_lesional_day151404.6884
GSM1296027I_lesional_day151302.2183
GSM1296032J_lesional_day151129.7681
GSM1296024K_lesional_day15877.6177
GSM1296031W_lesional_day151143.1781
GSM1296028X_lesional_day151096.1280
GSM1296029Z_lesional_day15908.2777
GSM1296026F_lesional_day151354.0284
GSM1296030O_lesional_day151323.283
GSM1296040S_lesional_day151380.8584
GSM1296036T_lesional_day151000.5579
GSM1296048V_lesional_day152386.7291
GSM1296059A_lesional_day431620.5386
GSM1296066G_lesional_day431823.0688
GSM1296060R_lesional_day431801.7788
GSM1296063U_lesional_day432015.2289
GSM1296064E_lesional_day432263.6790
GSM1296067H_lesional_day431855.0389
GSM1296062M_lesional_day431386.3384
GSM1296068Q_lesional_day431312.3384
GSM1296050C_lesional_day431350.484
GSM1296057D_lesional_day431368.8584
GSM1296052I_lesional_day431076.380
GSM1296054J_lesional_day43917.7478
GSM1296049K_lesional_day431038.5680
GSM1296055W_lesional_day431281.3783
GSM1296053X_lesional_day43949.1378
GSM1296058Z_lesional_day431148.0281
GSM1296051F_lesional_day431698.1486
GSM1296056O_lesional_day432064.6389
GSM1296065S_lesional_day431804.8588
GSM1296061T_lesional_day43851.3876
GSM1296095A_non-lesional_pre-dose1567.1186
GSM1296120B_non-lesional_pre-dose1578.3486
GSM1296077C_non-lesional_pre-dose1076.9780
GSM1296093D_non-lesional_pre-dose775.5775
GSM1296104E_non-lesional_pre-dose1261.4183
GSM1296079F_non-lesional_pre-dose1266.3182
GSM1296108G_non-lesional_pre-dose1490.3585
GSM1296110H_non-lesional_pre-dose1529.786
GSM1296081I_non-lesional_pre-dose561.6970
GSM1296091J_non-lesional_pre-dose1236.2382
GSM1296075K_non-lesional_pre-dose1481.7284
GSM1296112L_non-lesional_pre-dose1349.1885
GSM1296100M_non-lesional_pre-dose934.6378
GSM1296087O_non-lesional_pre-dose1456.8384
GSM1296118P_non-lesional_pre-dose1498.3986
GSM1296114Q_non-lesional_pre-dose1186.0182
GSM1296097R_non-lesional_pre-dose1321.9483
GSM1296106S_non-lesional_pre-dose1170.3682
GSM1296102U_non-lesional_pre-dose1129.5581
GSM1296122V_non-lesional_pre-dose1475.6585
GSM1296089W_non-lesional_pre-dose986.179
GSM1296083X_non-lesional_pre-dose592.7970
GSM1296116Y_non-lesional_pre-dose1561.2287
GSM1296085Z_non-lesional_pre-dose1066.9580