ProfileGDS5420 / 218359_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 33% 2% 2% 9% 38% 15% 27% 13% 12% 25% 24% 37% 7% 0% 27% 38% 34% 38% 25% 35% 4% 28% 22% 21% 35% 32% 24% 11% 30% 6% 40% 37% 11% 16% 24% 28% 45% 23% 25% 25% 34% 18% 24% 31% 35% 41% 30% 34% 21% 26% 30% 38% 26% 40% 13% 35% 36% 16% 33% 44% 25% 28% 32% 27% 39% 32% 46% 40% 44% 23% 38% 32% 39% 25% 17% 33% 41% 34% 18% 28% 28% 26% 9% 25% 26% 41% 28% 29% 18% 43% 34% 44% 35% 34% 43% 24% 32% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose56.6733
GSM1296119B_lesional_pre-dose2.252
GSM1296076C_lesional_pre-dose3.192
GSM1296092D_lesional_pre-dose7.339
GSM1296103E_lesional_pre-dose79.4538
GSM1296078F_lesional_pre-dose
GSM1296107G_lesional_pre-dose19.2215
GSM1296109H_lesional_pre-dose44.3527
GSM1296080I_lesional_pre-dose12.3113
GSM1296090J_lesional_pre-dose11.2212
GSM1296074K_lesional_pre-dose29.7825
GSM1296111L_lesional_pre-dose39.2624
GSM1296099M_lesional_pre-dose74.1437
GSM1296086O_lesional_pre-dose
GSM1296117P_lesional_pre-dose9.97
GSM1296113Q_lesional_pre-dose0.070
GSM1296096R_lesional_pre-dose35.0427
GSM1296105S_lesional_pre-dose85.9438
GSM1296098T_lesional_pre-dose67.3734
GSM1296101U_lesional_pre-dose80.138
GSM1296121V_lesional_pre-dose38.2225
GSM1296088W_lesional_pre-dose60.0135
GSM1296082X_lesional_pre-dose3.764
GSM1296115Y_lesional_pre-dose47.7228
GSM1296084Z_lesional_pre-dose29.8822
GSM1296072B_lesional_day828.3321
GSM1296069L_lesional_day882.8535
GSM1296071P_lesional_day868.5932
GSM1296070Y_lesional_day838.8824
GSM1296073V_lesional_day812.2811
GSM1296034A_lesional_day1551.5430
GSM1296041G_lesional_day156.676
GSM1296035R_lesional_day1584.0340
GSM1296038U_lesional_day1574.9537
GSM1296047B_lesional_day1514.4111
GSM1296039E_lesional_day1518.1916
GSM1296042H_lesional_day1539.6424
GSM1296043L_lesional_day1552.4428
GSM1296037M_lesional_day15132.645
GSM1296046P_lesional_day1538.623
GSM1296044Q_lesional_day1542.8325
GSM1296045Y_lesional_day1544.9425
GSM1296025C_lesional_day1562.1834
GSM1296033D_lesional_day1518.6318
GSM1296027I_lesional_day1525.1424
GSM1296032J_lesional_day1551.0231
GSM1296024K_lesional_day1562.2535
GSM1296031W_lesional_day15106.241
GSM1296028X_lesional_day1547.0530
GSM1296029Z_lesional_day1557.534
GSM1296026F_lesional_day1527.2421
GSM1296030O_lesional_day1529.2926
GSM1296040S_lesional_day1549.2530
GSM1296036T_lesional_day1586.6438
GSM1296048V_lesional_day154226
GSM1296059A_lesional_day4385.7140
GSM1296066G_lesional_day4316.0413
GSM1296060R_lesional_day4364.7435
GSM1296063U_lesional_day4373.3436
GSM1296064E_lesional_day4317.316
GSM1296067H_lesional_day4367.0533
GSM1296062M_lesional_day43120.0944
GSM1296068Q_lesional_day4347.4525
GSM1296050C_lesional_day4344.5228
GSM1296057D_lesional_day4351.1932
GSM1296052I_lesional_day4332.8927
GSM1296054J_lesional_day4390.2739
GSM1296049K_lesional_day4354.6532
GSM1296055W_lesional_day43142.5446
GSM1296053X_lesional_day4388.7140
GSM1296058Z_lesional_day43110.9644
GSM1296051F_lesional_day4329.423
GSM1296056O_lesional_day4371.9238
GSM1296065S_lesional_day4353.3532
GSM1296061T_lesional_day4389.4639
GSM1296095A_non-lesional_pre-dose31.4125
GSM1296120B_non-lesional_pre-dose23.0117
GSM1296077C_non-lesional_pre-dose54.6633
GSM1296093D_non-lesional_pre-dose101.8941
GSM1296104E_non-lesional_pre-dose60.4334
GSM1296079F_non-lesional_pre-dose21.4918
GSM1296108G_non-lesional_pre-dose46.0428
GSM1296110H_non-lesional_pre-dose50.0428
GSM1296081I_non-lesional_pre-dose29.6926
GSM1296091J_non-lesional_pre-dose8.429
GSM1296075K_non-lesional_pre-dose32.225
GSM1296112L_non-lesional_pre-dose48.4526
GSM1296100M_non-lesional_pre-dose103.7241
GSM1296087O_non-lesional_pre-dose35.0428
GSM1296118P_non-lesional_pre-dose56.8129
GSM1296114Q_non-lesional_pre-dose25.9218
GSM1296097R_non-lesional_pre-dose113.7143
GSM1296106S_non-lesional_pre-dose67.7734
GSM1296102U_non-lesional_pre-dose131.2844
GSM1296122V_non-lesional_pre-dose79.8135
GSM1296089W_non-lesional_pre-dose67.9634
GSM1296083X_non-lesional_pre-dose112.9543
GSM1296116Y_non-lesional_pre-dose42.724
GSM1296085Z_non-lesional_pre-dose52.9632