ProfileGDS5420 / 218062_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 84% 89% 92% 95% 89% 92% 93% 90% 82% 92% 90% 94% 94% 92% 90% 93% 94% 91% 83% 91% 95% 92% 93% 91% 94% 90% 93% 93% 93% 92% 80% 92% 93% 96% 94% 96% 93% 94% 96% 95% 96% 92% 85% 94% 88% 92% 83% 96% 93% 93% 84% 89% 91% 87% 92% 94% 93% 94% 96% 94% 94% 89% 96% 94% 97% 90% 89% 86% 97% 87% 95% 92% 95% 95% 83% 95% 95% 90% 91% 97% 89% 95% 91% 90% 95% 93% 95% 96% 93% 94% 95% 95% 94% 93% 96% 96% 96% 92% 93% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1359.2984
GSM1296119B_lesional_pre-dose2043.9589
GSM1296076C_lesional_pre-dose2873.592
GSM1296092D_lesional_pre-dose3739.9695
GSM1296103E_lesional_pre-dose2070.7789
GSM1296078F_lesional_pre-dose2835.4792
GSM1296107G_lesional_pre-dose2783.2493
GSM1296109H_lesional_pre-dose2067.2190
GSM1296080I_lesional_pre-dose1265.3282
GSM1296090J_lesional_pre-dose2602.0192
GSM1296074K_lesional_pre-dose2345.5190
GSM1296111L_lesional_pre-dose2903.5994
GSM1296099M_lesional_pre-dose2936.4494
GSM1296086O_lesional_pre-dose2826.4292
GSM1296117P_lesional_pre-dose2110.5890
GSM1296113Q_lesional_pre-dose2509.3293
GSM1296096R_lesional_pre-dose3030.1794
GSM1296105S_lesional_pre-dose2209.491
GSM1296098T_lesional_pre-dose1295.6783
GSM1296101U_lesional_pre-dose2306.0391
GSM1296121V_lesional_pre-dose3366.7795
GSM1296088W_lesional_pre-dose2513.5292
GSM1296082X_lesional_pre-dose3191.1493
GSM1296115Y_lesional_pre-dose2412.1591
GSM1296084Z_lesional_pre-dose3005.0194
GSM1296072B_lesional_day82157.6690
GSM1296069L_lesional_day82680.0793
GSM1296071P_lesional_day82544.7693
GSM1296070Y_lesional_day82586.3793
GSM1296073V_lesional_day82629.0492
GSM1296034A_lesional_day151037.2380
GSM1296041G_lesional_day152583.3992
GSM1296035R_lesional_day152858.9293
GSM1296038U_lesional_day154135.2596
GSM1296047B_lesional_day152835.0194
GSM1296039E_lesional_day154512.3896
GSM1296042H_lesional_day152585.8693
GSM1296043L_lesional_day152808.6594
GSM1296037M_lesional_day153975.7796
GSM1296046P_lesional_day153193.0395
GSM1296044Q_lesional_day153372.7896
GSM1296045Y_lesional_day152338.9492
GSM1296025C_lesional_day151537.4685
GSM1296033D_lesional_day152999.6694
GSM1296027I_lesional_day151926.7488
GSM1296032J_lesional_day152423.5292
GSM1296024K_lesional_day151271.6383
GSM1296031W_lesional_day153569.5796
GSM1296028X_lesional_day152641.8593
GSM1296029Z_lesional_day152742.9393
GSM1296026F_lesional_day151369.5684
GSM1296030O_lesional_day152123.4489
GSM1296040S_lesional_day152333.391
GSM1296036T_lesional_day151620.8887
GSM1296048V_lesional_day152667.3892
GSM1296059A_lesional_day433045.2894
GSM1296066G_lesional_day432814.0193
GSM1296060R_lesional_day432980.2894
GSM1296063U_lesional_day433940.1196
GSM1296064E_lesional_day433782.9194
GSM1296067H_lesional_day432705.0794
GSM1296062M_lesional_day431928.6789
GSM1296068Q_lesional_day433403.2196
GSM1296050C_lesional_day433263.2594
GSM1296057D_lesional_day434266.6997
GSM1296052I_lesional_day432262.7290
GSM1296054J_lesional_day431939.589
GSM1296049K_lesional_day431557.6286
GSM1296055W_lesional_day434469.4297
GSM1296053X_lesional_day431666.3687
GSM1296058Z_lesional_day433356.6395
GSM1296051F_lesional_day432706.4392
GSM1296056O_lesional_day433661.2395
GSM1296065S_lesional_day433107.1695
GSM1296061T_lesional_day431284.9283
GSM1296095A_non-lesional_pre-dose3865.0495
GSM1296120B_non-lesional_pre-dose3246.6995
GSM1296077C_non-lesional_pre-dose2168.7690
GSM1296093D_non-lesional_pre-dose2239.8191
GSM1296104E_non-lesional_pre-dose5433.3297
GSM1296079F_non-lesional_pre-dose2025.2589
GSM1296108G_non-lesional_pre-dose3430.9395
GSM1296110H_non-lesional_pre-dose2138.6591
GSM1296081I_non-lesional_pre-dose2235.9790
GSM1296091J_non-lesional_pre-dose3455.3995
GSM1296075K_non-lesional_pre-dose2936.7493
GSM1296112L_non-lesional_pre-dose3169.7195
GSM1296100M_non-lesional_pre-dose3778.0796
GSM1296087O_non-lesional_pre-dose2827.0493
GSM1296118P_non-lesional_pre-dose2835.6694
GSM1296114Q_non-lesional_pre-dose3354.295
GSM1296097R_non-lesional_pre-dose3422.2695
GSM1296106S_non-lesional_pre-dose2828.494
GSM1296102U_non-lesional_pre-dose2613.5293
GSM1296122V_non-lesional_pre-dose3711.5896
GSM1296089W_non-lesional_pre-dose3622.0296
GSM1296083X_non-lesional_pre-dose3995.6296
GSM1296116Y_non-lesional_pre-dose2269.292
GSM1296085Z_non-lesional_pre-dose2739.8893