ProfileGDS5420 / 217042_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 33% 45% 27% 20% 38% 25% 46% 46% 21% 15% 9% 46% 43% 26% 45% 46% 45% 35% 45% 37% 45% 13% 30% 44% 27% 38% 45% 44% 45% 37% 30% 50% 35% 33% 42% 42% 45% 43% 29% 44% 41% 40% 23% 17% 8% 10% 28% 22% 20% 14% 19% 2% 39% 31% 40% 38% 41% 35% 37% 46% 37% 32% 39% 21% 25% 13% 12% 2% 24% 25% 25% 12% 35% 33% 30% 38% 8% 23% 37% 9% 40% 44% 16% 25% 47% 32% 12% 40% 41% 32% 40% 25% 41% 11% 10% 47% 2% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose55.433
GSM1296119B_lesional_pre-dose131.545
GSM1296076C_lesional_pre-dose41.1627
GSM1296092D_lesional_pre-dose21.0320
GSM1296103E_lesional_pre-dose7838
GSM1296078F_lesional_pre-dose35.0625
GSM1296107G_lesional_pre-dose144.6446
GSM1296109H_lesional_pre-dose149.1646
GSM1296080I_lesional_pre-dose22.9721
GSM1296090J_lesional_pre-dose14.6815
GSM1296074K_lesional_pre-dose8.089
GSM1296111L_lesional_pre-dose145.4746
GSM1296099M_lesional_pre-dose114.3243
GSM1296086O_lesional_pre-dose34.4626
GSM1296117P_lesional_pre-dose140.5745
GSM1296113Q_lesional_pre-dose154.6146
GSM1296096R_lesional_pre-dose121.2245
GSM1296105S_lesional_pre-dose67.9535
GSM1296098T_lesional_pre-dose132.4845
GSM1296101U_lesional_pre-dose76.5137
GSM1296121V_lesional_pre-dose131.7645
GSM1296088W_lesional_pre-dose12.9613
GSM1296082X_lesional_pre-dose42.330
GSM1296115Y_lesional_pre-dose129.0944
GSM1296084Z_lesional_pre-dose40.8427
GSM1296072B_lesional_day888.6338
GSM1296069L_lesional_day8144.2945
GSM1296071P_lesional_day8138.7444
GSM1296070Y_lesional_day8145.6545
GSM1296073V_lesional_day878.5237
GSM1296034A_lesional_day1550.0230
GSM1296041G_lesional_day15179.2650
GSM1296035R_lesional_day155935
GSM1296038U_lesional_day1557.5333
GSM1296047B_lesional_day15114.4142
GSM1296039E_lesional_day15101.6342
GSM1296042H_lesional_day15141.4245
GSM1296043L_lesional_day15132.5443
GSM1296037M_lesional_day1547.729
GSM1296046P_lesional_day15137.8744
GSM1296044Q_lesional_day15119.4841
GSM1296045Y_lesional_day15114.1440
GSM1296025C_lesional_day1530.4823
GSM1296033D_lesional_day151817
GSM1296027I_lesional_day156.958
GSM1296032J_lesional_day158.9810
GSM1296024K_lesional_day1539.1628
GSM1296031W_lesional_day1528.5122
GSM1296028X_lesional_day1522.7720
GSM1296029Z_lesional_day1513.6214
GSM1296026F_lesional_day1523.8419
GSM1296030O_lesional_day151.812
GSM1296040S_lesional_day1591.0639
GSM1296036T_lesional_day1555.731
GSM1296048V_lesional_day15100.7440
GSM1296059A_lesional_day4373.0738
GSM1296066G_lesional_day43108.5441
GSM1296060R_lesional_day4363.2835
GSM1296063U_lesional_day4377.8337
GSM1296064E_lesional_day43132.9346
GSM1296067H_lesional_day4388.5537
GSM1296062M_lesional_day4354.3732
GSM1296068Q_lesional_day43106.0739
GSM1296050C_lesional_day4327.0821
GSM1296057D_lesional_day4330.4325
GSM1296052I_lesional_day4312.3813
GSM1296054J_lesional_day4313.1112
GSM1296049K_lesional_day432.312
GSM1296055W_lesional_day4332.2624
GSM1296053X_lesional_day43
GSM1296058Z_lesional_day4328.425
GSM1296051F_lesional_day4333.825
GSM1296056O_lesional_day4311.5612
GSM1296065S_lesional_day4368.3635
GSM1296061T_lesional_day4359.7133
GSM1296095A_non-lesional_pre-dose44.9730
GSM1296120B_non-lesional_pre-dose94.938
GSM1296077C_non-lesional_pre-dose8.458
GSM1296093D_non-lesional_pre-dose31.8123
GSM1296104E_non-lesional_pre-dose73.5137
GSM1296079F_non-lesional_pre-dose9.789
GSM1296108G_non-lesional_pre-dose99.9940
GSM1296110H_non-lesional_pre-dose143.5544
GSM1296081I_non-lesional_pre-dose
GSM1296091J_non-lesional_pre-dose15.8716
GSM1296075K_non-lesional_pre-dose32.3825
GSM1296112L_non-lesional_pre-dose169.9947
GSM1296100M_non-lesional_pre-dose54.5232
GSM1296087O_non-lesional_pre-dose11.3512
GSM1296118P_non-lesional_pre-dose111.7940
GSM1296114Q_non-lesional_pre-dose117.0841
GSM1296097R_non-lesional_pre-dose51.3732
GSM1296106S_non-lesional_pre-dose99.3340
GSM1296102U_non-lesional_pre-dose35.1725
GSM1296122V_non-lesional_pre-dose108.8241
GSM1296089W_non-lesional_pre-dose11.9711
GSM1296083X_non-lesional_pre-dose9.5410
GSM1296116Y_non-lesional_pre-dose169.6347
GSM1296085Z_non-lesional_pre-dose2.82