ProfileGDS5420 / 216904_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 24% 46% 5% 25% 26% 19% 39% 12% 42% 22% 48% 38% 1% 35% 38% 33% 37% 5% 35% 42% 31% 35% 41% 19% 43% 59% 44% 47% 43% 15% 41% 40% 51% 41% 47% 43% 53% 43% 45% 44% 54% 21% 22% 16% 15% 44% 28% 36% 16% 18% 33% 20% 51% 39% 31% 33% 53% 38% 47% 34% 46% 31% 52% 19% 13% 15% 66% 22% 56% 41% 45% 52% 24% 51% 46% 21% 16% 48% 16% 40% 43% 11% 21% 33% 52% 39% 23% 29% 37% 50% 45% 42% 41% 46% 31% 39% 26% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose31.2124
GSM1296119B_lesional_pre-dose140.4546
GSM1296076C_lesional_pre-dose6.45
GSM1296092D_lesional_pre-dose28.5725
GSM1296103E_lesional_pre-dose35.0926
GSM1296078F_lesional_pre-dose22.519
GSM1296107G_lesional_pre-dose95.4339
GSM1296109H_lesional_pre-dose14.6312
GSM1296080I_lesional_pre-dose
GSM1296090J_lesional_pre-dose93.3842
GSM1296074K_lesional_pre-dose24.5322
GSM1296111L_lesional_pre-dose164.6848
GSM1296099M_lesional_pre-dose78.4738
GSM1296086O_lesional_pre-dose1.111
GSM1296117P_lesional_pre-dose77.3235
GSM1296113Q_lesional_pre-dose98.9538
GSM1296096R_lesional_pre-dose56.0533
GSM1296105S_lesional_pre-dose78.1637
GSM1296098T_lesional_pre-dose7.165
GSM1296101U_lesional_pre-dose68.2835
GSM1296121V_lesional_pre-dose108.4142
GSM1296088W_lesional_pre-dose48.3931
GSM1296082X_lesional_pre-dose57.6535
GSM1296115Y_lesional_pre-dose106.2241
GSM1296084Z_lesional_pre-dose24.5719
GSM1296072B_lesional_day8118.9443
GSM1296069L_lesional_day8319.5459
GSM1296071P_lesional_day8142.1344
GSM1296070Y_lesional_day8166.4147
GSM1296073V_lesional_day8115.8843
GSM1296034A_lesional_day1516.8515
GSM1296041G_lesional_day15104.4541
GSM1296035R_lesional_day1582.7340
GSM1296038U_lesional_day15180.9451
GSM1296047B_lesional_day15112.3441
GSM1296039E_lesional_day15139.8647
GSM1296042H_lesional_day15125.7343
GSM1296043L_lesional_day15231.2253
GSM1296037M_lesional_day15121.6343
GSM1296046P_lesional_day15143.0845
GSM1296044Q_lesional_day15134.6544
GSM1296045Y_lesional_day15239.9154
GSM1296025C_lesional_day15
GSM1296033D_lesional_day1523.2621
GSM1296027I_lesional_day1522.2622
GSM1296032J_lesional_day1516.4516
GSM1296024K_lesional_day1515.1115
GSM1296031W_lesional_day15121.4544
GSM1296028X_lesional_day1538.628
GSM1296029Z_lesional_day1568.4536
GSM1296026F_lesional_day1518.4516
GSM1296030O_lesional_day1516.4318
GSM1296040S_lesional_day1560.0333
GSM1296036T_lesional_day1526.2220
GSM1296048V_lesional_day15189.8651
GSM1296059A_lesional_day4380.3439
GSM1296066G_lesional_day4362.0531
GSM1296060R_lesional_day4356.9633
GSM1296063U_lesional_day43209.953
GSM1296064E_lesional_day4379.438
GSM1296067H_lesional_day43165.1747
GSM1296062M_lesional_day4360.0734
GSM1296068Q_lesional_day43159.7346
GSM1296050C_lesional_day4351.9531
GSM1296057D_lesional_day43202.8552
GSM1296052I_lesional_day4319.319
GSM1296054J_lesional_day4313.913
GSM1296049K_lesional_day4315.9615
GSM1296055W_lesional_day43467.0466
GSM1296053X_lesional_day4326.2322
GSM1296058Z_lesional_day43240.1756
GSM1296051F_lesional_day4393.9641
GSM1296056O_lesional_day43119.2845
GSM1296065S_lesional_day43199.8552
GSM1296061T_lesional_day4334.2424
GSM1296095A_non-lesional_pre-dose176.9751
GSM1296120B_non-lesional_pre-dose149.8946
GSM1296077C_non-lesional_pre-dose23.8521
GSM1296093D_non-lesional_pre-dose18.3116
GSM1296104E_non-lesional_pre-dose152.8748
GSM1296079F_non-lesional_pre-dose19.1716
GSM1296108G_non-lesional_pre-dose103.1840
GSM1296110H_non-lesional_pre-dose128.443
GSM1296081I_non-lesional_pre-dose9.7611
GSM1296091J_non-lesional_pre-dose23.5321
GSM1296075K_non-lesional_pre-dose57.133
GSM1296112L_non-lesional_pre-dose222.752
GSM1296100M_non-lesional_pre-dose88.9339
GSM1296087O_non-lesional_pre-dose25.4423
GSM1296118P_non-lesional_pre-dose55.4329
GSM1296114Q_non-lesional_pre-dose90.4637
GSM1296097R_non-lesional_pre-dose171.9750
GSM1296106S_non-lesional_pre-dose138.9945
GSM1296102U_non-lesional_pre-dose114.8942
GSM1296122V_non-lesional_pre-dose108.0241
GSM1296089W_non-lesional_pre-dose139.5546
GSM1296083X_non-lesional_pre-dose49.2331
GSM1296116Y_non-lesional_pre-dose109.0839
GSM1296085Z_non-lesional_pre-dose36.6526