ProfileGDS5420 / 216121_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 62% 44% 44% 43% 51% 69% 51% 48% 51% 47% 70% 49% 49% 68% 71% 42% 51% 51% 40% 56% 52% 54% 63% 53% 61% 69% 59% 65% 46% 38% 70% 35% 52% 61% 41% 72% 70% 17% 70% 72% 65% 49% 45% 45% 46% 42% 50% 46% 47% 45% 42% 43% 51% 49% 26% 67% 39% 44% 46% 60% 44% 67% 50% 31% 43% 50% 45% 47% 43% 26% 46% 29% 46% 51% 49% 65% 39% 46% 49% 52% 62% 67% 26% 52% 47% 69% 38% 39% 68% 77% 45% 52% 43% 51% 57% 40% 73% 37% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose155.3148
GSM1296119B_lesional_pre-dose347.0462
GSM1296076C_lesional_pre-dose111.6544
GSM1296092D_lesional_pre-dose100.9344
GSM1296103E_lesional_pre-dose110.9443
GSM1296078F_lesional_pre-dose162.4251
GSM1296107G_lesional_pre-dose531.5569
GSM1296109H_lesional_pre-dose196.1651
GSM1296080I_lesional_pre-dose139.0148
GSM1296090J_lesional_pre-dose175.2751
GSM1296074K_lesional_pre-dose118.4247
GSM1296111L_lesional_pre-dose581.8770
GSM1296099M_lesional_pre-dose163.1549
GSM1296086O_lesional_pre-dose147.4949
GSM1296117P_lesional_pre-dose503.1468
GSM1296113Q_lesional_pre-dose614.5171
GSM1296096R_lesional_pre-dose102.542
GSM1296105S_lesional_pre-dose193.5651
GSM1296098T_lesional_pre-dose183.5851
GSM1296101U_lesional_pre-dose91.7140
GSM1296121V_lesional_pre-dose247.0456
GSM1296088W_lesional_pre-dose189.4352
GSM1296082X_lesional_pre-dose195.1854
GSM1296115Y_lesional_pre-dose383.7463
GSM1296084Z_lesional_pre-dose201.853
GSM1296072B_lesional_day8349.6561
GSM1296069L_lesional_day8548.7469
GSM1296071P_lesional_day8313.3559
GSM1296070Y_lesional_day8440.1965
GSM1296073V_lesional_day8137.9646
GSM1296034A_lesional_day1583.3538
GSM1296041G_lesional_day15554.7370
GSM1296035R_lesional_day1561.0735
GSM1296038U_lesional_day15192.752
GSM1296047B_lesional_day15355.9161
GSM1296039E_lesional_day1598.2341
GSM1296042H_lesional_day15632.4772
GSM1296043L_lesional_day15598.2170
GSM1296037M_lesional_day1521.7117
GSM1296046P_lesional_day15590.6170
GSM1296044Q_lesional_day15660.5672
GSM1296045Y_lesional_day15430.665
GSM1296025C_lesional_day15153.4549
GSM1296033D_lesional_day15123.6145
GSM1296027I_lesional_day15107.5845
GSM1296032J_lesional_day15131.8146
GSM1296024K_lesional_day1599.9442
GSM1296031W_lesional_day15186.2150
GSM1296028X_lesional_day15133.5546
GSM1296029Z_lesional_day15140.7747
GSM1296026F_lesional_day15124.5145
GSM1296030O_lesional_day158742
GSM1296040S_lesional_day15115.6443
GSM1296036T_lesional_day15199.1251
GSM1296048V_lesional_day15167.6749
GSM1296059A_lesional_day4333.5126
GSM1296066G_lesional_day43482.2767
GSM1296060R_lesional_day4382.4339
GSM1296063U_lesional_day43122.144
GSM1296064E_lesional_day43126.9646
GSM1296067H_lesional_day43351.0760
GSM1296062M_lesional_day43116.4544
GSM1296068Q_lesional_day43506.6267
GSM1296050C_lesional_day43174.0850
GSM1296057D_lesional_day4347.0531
GSM1296052I_lesional_day4399.643
GSM1296054J_lesional_day43183.9750
GSM1296049K_lesional_day43122.2745
GSM1296055W_lesional_day43150.0347
GSM1296053X_lesional_day43112.9343
GSM1296058Z_lesional_day4330.2226
GSM1296051F_lesional_day43128.8246
GSM1296056O_lesional_day4338.0329
GSM1296065S_lesional_day43142.6146
GSM1296061T_lesional_day43189.6451
GSM1296095A_non-lesional_pre-dose162.2449
GSM1296120B_non-lesional_pre-dose442.3465
GSM1296077C_non-lesional_pre-dose83.1539
GSM1296093D_non-lesional_pre-dose146.7646
GSM1296104E_non-lesional_pre-dose167.5449
GSM1296079F_non-lesional_pre-dose184.0852
GSM1296108G_non-lesional_pre-dose372.162
GSM1296110H_non-lesional_pre-dose507.9167
GSM1296081I_non-lesional_pre-dose29.9426
GSM1296091J_non-lesional_pre-dose191.6752
GSM1296075K_non-lesional_pre-dose128.7147
GSM1296112L_non-lesional_pre-dose553.0469
GSM1296100M_non-lesional_pre-dose84.5638
GSM1296087O_non-lesional_pre-dose73.1839
GSM1296118P_non-lesional_pre-dose521.8568
GSM1296114Q_non-lesional_pre-dose844.277
GSM1296097R_non-lesional_pre-dose128.3645
GSM1296106S_non-lesional_pre-dose207.4452
GSM1296102U_non-lesional_pre-dose123.4643
GSM1296122V_non-lesional_pre-dose194.6951
GSM1296089W_non-lesional_pre-dose272.3457
GSM1296083X_non-lesional_pre-dose89.2740
GSM1296116Y_non-lesional_pre-dose688.0473
GSM1296085Z_non-lesional_pre-dose73.7337