ProfileGDS5420 / 214738_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 30% 49% 41% 36% 25% 41% 43% 34% 24% 42% 36% 52% 37% 39% 49% 47% 40% 35% 42% 27% 40% 31% 44% 42% 25% 53% 51% 41% 45% 50% 25% 40% 42% 41% 51% 38% 44% 49% 35% 45% 44% 44% 32% 36% 31% 43% 25% 43% 36% 27% 22% 30% 26% 34% 40% 31% 44% 38% 47% 47% 34% 31% 46% 38% 39% 29% 42% 30% 35% 28% 42% 29% 32% 52% 31% 45% 52% 27% 36% 40% 37% 43% 43% 19% 50% 43% 52% 38% 22% 40% 46% 40% 45% 38% 50% 42% 28% 43% 23% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose46.0130
GSM1296119B_lesional_pre-dose166.2549
GSM1296076C_lesional_pre-dose92.241
GSM1296092D_lesional_pre-dose59.9136
GSM1296103E_lesional_pre-dose32.5925
GSM1296078F_lesional_pre-dose88.1141
GSM1296107G_lesional_pre-dose120.2243
GSM1296109H_lesional_pre-dose71.3334
GSM1296080I_lesional_pre-dose27.6824
GSM1296090J_lesional_pre-dose97.8142
GSM1296074K_lesional_pre-dose61.3936
GSM1296111L_lesional_pre-dose208.8752
GSM1296099M_lesional_pre-dose77.637
GSM1296086O_lesional_pre-dose80.4639
GSM1296117P_lesional_pre-dose171.949
GSM1296113Q_lesional_pre-dose165.7347
GSM1296096R_lesional_pre-dose85.4140
GSM1296105S_lesional_pre-dose69.6535
GSM1296098T_lesional_pre-dose111.7942
GSM1296101U_lesional_pre-dose38.3927
GSM1296121V_lesional_pre-dose97.2640
GSM1296088W_lesional_pre-dose48.8131
GSM1296082X_lesional_pre-dose106.6344
GSM1296115Y_lesional_pre-dose113.6642
GSM1296084Z_lesional_pre-dose34.8325
GSM1296072B_lesional_day8219.5153
GSM1296069L_lesional_day8209.7551
GSM1296071P_lesional_day8120.8841
GSM1296070Y_lesional_day8149.4945
GSM1296073V_lesional_day8168.1650
GSM1296034A_lesional_day1536.4425
GSM1296041G_lesional_day15100.8640
GSM1296035R_lesional_day1594.2642
GSM1296038U_lesional_day1599.2641
GSM1296047B_lesional_day15193.4851
GSM1296039E_lesional_day1576.7938
GSM1296042H_lesional_day15134.0144
GSM1296043L_lesional_day15187.349
GSM1296037M_lesional_day1570.8835
GSM1296046P_lesional_day15150.1145
GSM1296044Q_lesional_day15138.3144
GSM1296045Y_lesional_day15141.2144
GSM1296025C_lesional_day1552.4532
GSM1296033D_lesional_day1566.6936
GSM1296027I_lesional_day1540.6831
GSM1296032J_lesional_day15109.9143
GSM1296024K_lesional_day1531.625
GSM1296031W_lesional_day15114.6243
GSM1296028X_lesional_day1568.5136
GSM1296029Z_lesional_day1537.5827
GSM1296026F_lesional_day1529.4822
GSM1296030O_lesional_day1538.8830
GSM1296040S_lesional_day1537.8326
GSM1296036T_lesional_day1569.4434
GSM1296048V_lesional_day1598.3140
GSM1296059A_lesional_day4347.2731
GSM1296066G_lesional_day43130.3744
GSM1296060R_lesional_day4379.7538
GSM1296063U_lesional_day43145.9947
GSM1296064E_lesional_day43135.0647
GSM1296067H_lesional_day4371.1734
GSM1296062M_lesional_day4350.8331
GSM1296068Q_lesional_day43161.3646
GSM1296050C_lesional_day4382.6738
GSM1296057D_lesional_day4385.439
GSM1296052I_lesional_day4336.9629
GSM1296054J_lesional_day43110.8942
GSM1296049K_lesional_day4346.7230
GSM1296055W_lesional_day4370.9135
GSM1296053X_lesional_day4340.0728
GSM1296058Z_lesional_day4399.642
GSM1296051F_lesional_day4344.9929
GSM1296056O_lesional_day4349.9232
GSM1296065S_lesional_day43204.6452
GSM1296061T_lesional_day4354.1831
GSM1296095A_non-lesional_pre-dose117.945
GSM1296120B_non-lesional_pre-dose205.3952
GSM1296077C_non-lesional_pre-dose37.2127
GSM1296093D_non-lesional_pre-dose72.8636
GSM1296104E_non-lesional_pre-dose94.6340
GSM1296079F_non-lesional_pre-dose73.3937
GSM1296108G_non-lesional_pre-dose118.4443
GSM1296110H_non-lesional_pre-dose135.9743
GSM1296081I_non-lesional_pre-dose18.6519
GSM1296091J_non-lesional_pre-dose166.550
GSM1296075K_non-lesional_pre-dose104.0343
GSM1296112L_non-lesional_pre-dose218.8952
GSM1296100M_non-lesional_pre-dose84.2838
GSM1296087O_non-lesional_pre-dose24.0322
GSM1296118P_non-lesional_pre-dose110.1840
GSM1296114Q_non-lesional_pre-dose152.0246
GSM1296097R_non-lesional_pre-dose92.5140
GSM1296106S_non-lesional_pre-dose134.345
GSM1296102U_non-lesional_pre-dose87.5738
GSM1296122V_non-lesional_pre-dose187.9950
GSM1296089W_non-lesional_pre-dose114.8342
GSM1296083X_non-lesional_pre-dose39.1228
GSM1296116Y_non-lesional_pre-dose133.3643
GSM1296085Z_non-lesional_pre-dose29.0723