ProfileGDS5420 / 213808_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 61% 56% 60% 71% 64% 75% 59% 58% 67% 57% 62% 60% 72% 75% 57% 32% 54% 66% 68% 39% 62% 72% 61% 50% 64% 58% 56% 54% 53% 56% 57% 64% 58% 52% 51% 62% 61% 57% 53% 50% 31% 48% 70% 74% 65% 60% 63% 60% 58% 61% 80% 75% 58% 64% 55% 58% 58% 59% 50% 60% 59% 67% 33% 63% 63% 63% 58% 65% 58% 64% 39% 75% 72% 57% 68% 51% 46% 64% 59% 46% 75% 38% 39% 54% 50% 51% 39% 51% 56% 49% 28% 49% 50% 42% 59% 54% 57% 34% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose339.1661
GSM1296119B_lesional_pre-dose258.6856
GSM1296076C_lesional_pre-dose285.0760
GSM1296092D_lesional_pre-dose605.7271
GSM1296103E_lesional_pre-dose411.7464
GSM1296078F_lesional_pre-dose761.7375
GSM1296107G_lesional_pre-dose306.9159
GSM1296109H_lesional_pre-dose303.5958
GSM1296080I_lesional_pre-dose488.3867
GSM1296090J_lesional_pre-dose241.9357
GSM1296074K_lesional_pre-dose321.9162
GSM1296111L_lesional_pre-dose318.460
GSM1296099M_lesional_pre-dose649.3472
GSM1296086O_lesional_pre-dose769.5875
GSM1296117P_lesional_pre-dose283.2957
GSM1296113Q_lesional_pre-dose72.2532
GSM1296096R_lesional_pre-dose219.6854
GSM1296105S_lesional_pre-dose455.7666
GSM1296098T_lesional_pre-dose503.368
GSM1296101U_lesional_pre-dose89.939
GSM1296121V_lesional_pre-dose362.662
GSM1296088W_lesional_pre-dose666.5272
GSM1296082X_lesional_pre-dose314.9661
GSM1296115Y_lesional_pre-dose179.8150
GSM1296084Z_lesional_pre-dose388.6164
GSM1296072B_lesional_day8287.5858
GSM1296069L_lesional_day8269.3156
GSM1296071P_lesional_day8253.0154
GSM1296070Y_lesional_day8221.7453
GSM1296073V_lesional_day8246.5356
GSM1296034A_lesional_day15280.0257
GSM1296041G_lesional_day15400.3264
GSM1296035R_lesional_day15280.4158
GSM1296038U_lesional_day15189.8452
GSM1296047B_lesional_day15191.9251
GSM1296039E_lesional_day15345.5762
GSM1296042H_lesional_day15345.3361
GSM1296043L_lesional_day15291.0357
GSM1296037M_lesional_day15216.3253
GSM1296046P_lesional_day15189.6350
GSM1296044Q_lesional_day1562.5931
GSM1296045Y_lesional_day15174.0148
GSM1296025C_lesional_day15591.3570
GSM1296033D_lesional_day15743.0174
GSM1296027I_lesional_day15404.8365
GSM1296032J_lesional_day15324.5860
GSM1296024K_lesional_day15369.2763
GSM1296031W_lesional_day15336.4360
GSM1296028X_lesional_day15273.9758
GSM1296029Z_lesional_day15343.4561
GSM1296026F_lesional_day151041.9280
GSM1296030O_lesional_day15806.1175
GSM1296040S_lesional_day15295.6258
GSM1296036T_lesional_day15417.364
GSM1296048V_lesional_day15239.5655
GSM1296059A_lesional_day43269.6358
GSM1296066G_lesional_day4329458
GSM1296060R_lesional_day43299.2159
GSM1296063U_lesional_day43169.9450
GSM1296064E_lesional_day43311.6160
GSM1296067H_lesional_day43318.1359
GSM1296062M_lesional_day43492.8767
GSM1296068Q_lesional_day4376.1933
GSM1296050C_lesional_day43371.5563
GSM1296057D_lesional_day43397.4963
GSM1296052I_lesional_day43378.4863
GSM1296054J_lesional_day43298.8358
GSM1296049K_lesional_day43423.0565
GSM1296055W_lesional_day43286.2858
GSM1296053X_lesional_day43398.6964
GSM1296058Z_lesional_day4377.6139
GSM1296051F_lesional_day43773.3875
GSM1296056O_lesional_day43628.2872
GSM1296065S_lesional_day43272.8857
GSM1296061T_lesional_day43530.668
GSM1296095A_non-lesional_pre-dose179.7951
GSM1296120B_non-lesional_pre-dose146.0146
GSM1296077C_non-lesional_pre-dose395.3264
GSM1296093D_non-lesional_pre-dose316.0559
GSM1296104E_non-lesional_pre-dose136.8346
GSM1296079F_non-lesional_pre-dose791.4675
GSM1296108G_non-lesional_pre-dose92.3738
GSM1296110H_non-lesional_pre-dose105.7739
GSM1296081I_non-lesional_pre-dose202.0654
GSM1296091J_non-lesional_pre-dose165.2150
GSM1296075K_non-lesional_pre-dose166.5951
GSM1296112L_non-lesional_pre-dose111.1739
GSM1296100M_non-lesional_pre-dose19851
GSM1296087O_non-lesional_pre-dose229.8756
GSM1296118P_non-lesional_pre-dose189.3849
GSM1296114Q_non-lesional_pre-dose50.928
GSM1296097R_non-lesional_pre-dose162.6249
GSM1296106S_non-lesional_pre-dose187.150
GSM1296102U_non-lesional_pre-dose114.0142
GSM1296122V_non-lesional_pre-dose302.5659
GSM1296089W_non-lesional_pre-dose234.954
GSM1296083X_non-lesional_pre-dose269.0157
GSM1296116Y_non-lesional_pre-dose80.7734
GSM1296085Z_non-lesional_pre-dose160.9149