ProfileGDS5420 / 213519_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 49% 72% 63% 61% 47% 64% 63% 57% 40% 67% 62% 79% 62% 54% 65% 64% 64% 65% 31% 67% 70% 61% 58% 65% 64% 69% 86% 77% 77% 69% 46% 61% 65% 69% 68% 70% 73% 79% 66% 73% 66% 78% 61% 63% 58% 61% 56% 67% 58% 71% 74% 55% 59% 44% 78% 66% 57% 62% 78% 62% 75% 52% 69% 78% 70% 64% 58% 58% 79% 55% 85% 74% 68% 70% 36% 70% 71% 61% 53% 68% 62% 66% 69% 57% 51% 67% 84% 64% 65% 65% 64% 75% 68% 74% 67% 70% 51% 70% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose166.2849
GSM1296119B_lesional_pre-dose646.5872
GSM1296076C_lesional_pre-dose34763
GSM1296092D_lesional_pre-dose308.7461
GSM1296103E_lesional_pre-dose143.4147
GSM1296078F_lesional_pre-dose374.7864
GSM1296107G_lesional_pre-dose386.9463
GSM1296109H_lesional_pre-dose282.7757
GSM1296080I_lesional_pre-dose84.4340
GSM1296090J_lesional_pre-dose480.667
GSM1296074K_lesional_pre-dose326.3362
GSM1296111L_lesional_pre-dose971.8279
GSM1296099M_lesional_pre-dose374.5662
GSM1296086O_lesional_pre-dose209.5554
GSM1296117P_lesional_pre-dose424.2965
GSM1296113Q_lesional_pre-dose425.6364
GSM1296096R_lesional_pre-dose403.0164
GSM1296105S_lesional_pre-dose449.6865
GSM1296098T_lesional_pre-dose56.1831
GSM1296101U_lesional_pre-dose486.7267
GSM1296121V_lesional_pre-dose580.6570
GSM1296088W_lesional_pre-dose33961
GSM1296082X_lesional_pre-dose254.7358
GSM1296115Y_lesional_pre-dose425.4465
GSM1296084Z_lesional_pre-dose397.6364
GSM1296072B_lesional_day8554.4869
GSM1296069L_lesional_day81464.0186
GSM1296071P_lesional_day8851.677
GSM1296070Y_lesional_day8850.377
GSM1296073V_lesional_day8530.1869
GSM1296034A_lesional_day15146.3446
GSM1296041G_lesional_day15334.4361
GSM1296035R_lesional_day15443.7265
GSM1296038U_lesional_day15550.5469
GSM1296047B_lesional_day15514.2168
GSM1296039E_lesional_day15543.6970
GSM1296042H_lesional_day15698.4973
GSM1296043L_lesional_day15992.5479
GSM1296037M_lesional_day15449.1166
GSM1296046P_lesional_day15703.973
GSM1296044Q_lesional_day15472.3866
GSM1296045Y_lesional_day15921.8378
GSM1296025C_lesional_day15335.8461
GSM1296033D_lesional_day15384.463
GSM1296027I_lesional_day15257.0258
GSM1296032J_lesional_day15343.9661
GSM1296024K_lesional_day15237.0956
GSM1296031W_lesional_day15491.767
GSM1296028X_lesional_day15272.9558
GSM1296029Z_lesional_day15623.6171
GSM1296026F_lesional_day15750.4974
GSM1296030O_lesional_day15213.9855
GSM1296040S_lesional_day15301.3759
GSM1296036T_lesional_day15131.2744
GSM1296048V_lesional_day15938.7678
GSM1296059A_lesional_day43455.2866
GSM1296066G_lesional_day43277.6657
GSM1296060R_lesional_day43373.1462
GSM1296063U_lesional_day43943.8778
GSM1296064E_lesional_day43351.6662
GSM1296067H_lesional_day43782.4875
GSM1296062M_lesional_day43201.1852
GSM1296068Q_lesional_day43562.3269
GSM1296050C_lesional_day43917.0978
GSM1296057D_lesional_day43594.6570
GSM1296052I_lesional_day43402.8864
GSM1296054J_lesional_day43295.8858
GSM1296049K_lesional_day43275.5858
GSM1296055W_lesional_day431001.5379
GSM1296053X_lesional_day43232.2255
GSM1296058Z_lesional_day431487.4785
GSM1296051F_lesional_day43701.1174
GSM1296056O_lesional_day43487.8868
GSM1296065S_lesional_day43590.170
GSM1296061T_lesional_day4371.9536
GSM1296095A_non-lesional_pre-dose567.9970
GSM1296120B_non-lesional_pre-dose601.4671
GSM1296077C_non-lesional_pre-dose327.3761
GSM1296093D_non-lesional_pre-dose216.7853
GSM1296104E_non-lesional_pre-dose505.7568
GSM1296079F_non-lesional_pre-dose350.6162
GSM1296108G_non-lesional_pre-dose452.0266
GSM1296110H_non-lesional_pre-dose572.7169
GSM1296081I_non-lesional_pre-dose254.2857
GSM1296091J_non-lesional_pre-dose176.3751
GSM1296075K_non-lesional_pre-dose459.667
GSM1296112L_non-lesional_pre-dose1265.7384
GSM1296100M_non-lesional_pre-dose426.0364
GSM1296087O_non-lesional_pre-dose412.2965
GSM1296118P_non-lesional_pre-dose446.4965
GSM1296114Q_non-lesional_pre-dose422.8564
GSM1296097R_non-lesional_pre-dose768.5875
GSM1296106S_non-lesional_pre-dose512.1168
GSM1296102U_non-lesional_pre-dose736.4974
GSM1296122V_non-lesional_pre-dose484.2167
GSM1296089W_non-lesional_pre-dose590.4670
GSM1296083X_non-lesional_pre-dose18851
GSM1296116Y_non-lesional_pre-dose582.1970
GSM1296085Z_non-lesional_pre-dose327.1260