ProfileGDS5420 / 212729_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 71% 72% 78% 75% 72% 78% 70% 72% 60% 78% 80% 72% 69% 67% 75% 73% 74% 63% 65% 64% 70% 69% 81% 78% 62% 65% 58% 64% 71% 77% 56% 80% 74% 65% 62% 78% 66% 64% 58% 67% 62% 68% 54% 60% 53% 60% 52% 58% 58% 54% 66% 60% 66% 62% 72% 72% 70% 67% 74% 82% 54% 61% 58% 61% 66% 50% 58% 56% 61% 49% 62% 70% 78% 73% 62% 68% 63% 61% 50% 67% 58% 61% 58% 55% 72% 63% 61% 62% 57% 62% 58% 60% 62% 47% 56% 59% 48% 61% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose619.7671
GSM1296119B_lesional_pre-dose637.9672
GSM1296076C_lesional_pre-dose929.1678
GSM1296092D_lesional_pre-dose804.1275
GSM1296103E_lesional_pre-dose650.8472
GSM1296078F_lesional_pre-dose898.6578
GSM1296107G_lesional_pre-dose563.5770
GSM1296109H_lesional_pre-dose671.4772
GSM1296080I_lesional_pre-dose307.9960
GSM1296090J_lesional_pre-dose974.9578
GSM1296074K_lesional_pre-dose1061.8580
GSM1296111L_lesional_pre-dose626.8272
GSM1296099M_lesional_pre-dose535.8969
GSM1296086O_lesional_pre-dose475.0667
GSM1296117P_lesional_pre-dose746.2675
GSM1296113Q_lesional_pre-dose700.5473
GSM1296096R_lesional_pre-dose733.6674
GSM1296105S_lesional_pre-dose386.1263
GSM1296098T_lesional_pre-dose433.5865
GSM1296101U_lesional_pre-dose402.5964
GSM1296121V_lesional_pre-dose565.6870
GSM1296088W_lesional_pre-dose531.4869
GSM1296082X_lesional_pre-dose1144.3881
GSM1296115Y_lesional_pre-dose933.9478
GSM1296084Z_lesional_pre-dose361.0462
GSM1296072B_lesional_day8420.7865
GSM1296069L_lesional_day8301.0458
GSM1296071P_lesional_day8419.9864
GSM1296070Y_lesional_day8614.6671
GSM1296073V_lesional_day8852.4477
GSM1296034A_lesional_day15267.2456
GSM1296041G_lesional_day151048.2380
GSM1296035R_lesional_day15728.374
GSM1296038U_lesional_day15427.4965
GSM1296047B_lesional_day15363.7562
GSM1296039E_lesional_day15917.5978
GSM1296042H_lesional_day15458.566
GSM1296043L_lesional_day15429.7164
GSM1296037M_lesional_day15295.8558
GSM1296046P_lesional_day15484.3267
GSM1296044Q_lesional_day15369.2362
GSM1296045Y_lesional_day15509.2968
GSM1296025C_lesional_day15211.9554
GSM1296033D_lesional_day15322.6660
GSM1296027I_lesional_day15184.7353
GSM1296032J_lesional_day15329.3460
GSM1296024K_lesional_day15186.252
GSM1296031W_lesional_day15297.7758
GSM1296028X_lesional_day15285.1558
GSM1296029Z_lesional_day15225.0454
GSM1296026F_lesional_day15441.1666
GSM1296030O_lesional_day15292.3160
GSM1296040S_lesional_day15465.166
GSM1296036T_lesional_day15366.4862
GSM1296048V_lesional_day15643.3472
GSM1296059A_lesional_day43637.9272
GSM1296066G_lesional_day43575.6170
GSM1296060R_lesional_day43481.1367
GSM1296063U_lesional_day43718.9574
GSM1296064E_lesional_day431193.0782
GSM1296067H_lesional_day43248.554
GSM1296062M_lesional_day43340.8961
GSM1296068Q_lesional_day43313.8358
GSM1296050C_lesional_day43326.861
GSM1296057D_lesional_day43471.2266
GSM1296052I_lesional_day43163.0550
GSM1296054J_lesional_day43289.6358
GSM1296049K_lesional_day43249.1656
GSM1296055W_lesional_day43345.5961
GSM1296053X_lesional_day43159.349
GSM1296058Z_lesional_day43363.662
GSM1296051F_lesional_day43539.4270
GSM1296056O_lesional_day43917.1278
GSM1296065S_lesional_day43713.2673
GSM1296061T_lesional_day43375.6362
GSM1296095A_non-lesional_pre-dose508.2868
GSM1296120B_non-lesional_pre-dose380.2263
GSM1296077C_non-lesional_pre-dose323.1161
GSM1296093D_non-lesional_pre-dose180.1750
GSM1296104E_non-lesional_pre-dose486.8567
GSM1296079F_non-lesional_pre-dose273.0358
GSM1296108G_non-lesional_pre-dose335.5661
GSM1296110H_non-lesional_pre-dose310.6158
GSM1296081I_non-lesional_pre-dose220.0855
GSM1296091J_non-lesional_pre-dose655.5872
GSM1296075K_non-lesional_pre-dose358.8463
GSM1296112L_non-lesional_pre-dose365.1761
GSM1296100M_non-lesional_pre-dose369.0962
GSM1296087O_non-lesional_pre-dose235.8157
GSM1296118P_non-lesional_pre-dose368.0662
GSM1296114Q_non-lesional_pre-dose299.3558
GSM1296097R_non-lesional_pre-dose327.860
GSM1296106S_non-lesional_pre-dose373.2962
GSM1296102U_non-lesional_pre-dose155.8447
GSM1296122V_non-lesional_pre-dose266.5956
GSM1296089W_non-lesional_pre-dose318.1959
GSM1296083X_non-lesional_pre-dose156.2548
GSM1296116Y_non-lesional_pre-dose362.4561
GSM1296085Z_non-lesional_pre-dose317.7960