ProfileGDS5420 / 212728_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 81% 87% 88% 86% 82% 85% 84% 80% 66% 88% 88% 84% 82% 79% 85% 87% 85% 79% 76% 83% 85% 74% 87% 87% 75% 88% 78% 82% 85% 90% 67% 87% 88% 78% 87% 89% 83% 83% 84% 85% 81% 84% 70% 77% 72% 80% 71% 72% 75% 67% 74% 72% 76% 70% 88% 85% 84% 84% 86% 88% 74% 71% 77% 77% 91% 68% 74% 70% 82% 67% 87% 80% 90% 90% 71% 87% 85% 72% 68% 87% 74% 82% 76% 65% 85% 79% 82% 87% 73% 84% 82% 84% 82% 75% 78% 78% 67% 80% 78% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1141.3281
GSM1296119B_lesional_pre-dose1651.3687
GSM1296076C_lesional_pre-dose1916.8688
GSM1296092D_lesional_pre-dose1629.6886
GSM1296103E_lesional_pre-dose1216.9982
GSM1296078F_lesional_pre-dose1602.485
GSM1296107G_lesional_pre-dose1366.4684
GSM1296109H_lesional_pre-dose1033.2280
GSM1296080I_lesional_pre-dose433.9966
GSM1296090J_lesional_pre-dose1862.988
GSM1296074K_lesional_pre-dose1972.5388
GSM1296111L_lesional_pre-dose1351.0484
GSM1296099M_lesional_pre-dose1200.0282
GSM1296086O_lesional_pre-dose985.379
GSM1296117P_lesional_pre-dose1456.4485
GSM1296113Q_lesional_pre-dose1608.6587
GSM1296096R_lesional_pre-dose1494.6585
GSM1296105S_lesional_pre-dose974.0879
GSM1296098T_lesional_pre-dose816.7576
GSM1296101U_lesional_pre-dose1257.5783
GSM1296121V_lesional_pre-dose1507.4485
GSM1296088W_lesional_pre-dose733.9674
GSM1296082X_lesional_pre-dose1869.4387
GSM1296115Y_lesional_pre-dose1688.9387
GSM1296084Z_lesional_pre-dose796.6875
GSM1296072B_lesional_day81776.3588
GSM1296069L_lesional_day8908.2678
GSM1296071P_lesional_day81147.2882
GSM1296070Y_lesional_day81459.8285
GSM1296073V_lesional_day82232.3690
GSM1296034A_lesional_day15506.2467
GSM1296041G_lesional_day151756.9287
GSM1296035R_lesional_day151857.288
GSM1296038U_lesional_day15956.3778
GSM1296047B_lesional_day151606.6887
GSM1296039E_lesional_day152030.7489
GSM1296042H_lesional_day151224.1283
GSM1296043L_lesional_day151221.6683
GSM1296037M_lesional_day151312.2584
GSM1296046P_lesional_day151374.1285
GSM1296044Q_lesional_day151103.3881
GSM1296045Y_lesional_day151356.7784
GSM1296025C_lesional_day15589.7870
GSM1296033D_lesional_day15905.0577
GSM1296027I_lesional_day15653.6272
GSM1296032J_lesional_day151102.0380
GSM1296024K_lesional_day15613.6871
GSM1296031W_lesional_day15644.3472
GSM1296028X_lesional_day15791.6875
GSM1296029Z_lesional_day15479.8167
GSM1296026F_lesional_day15721.9374
GSM1296030O_lesional_day15644.972
GSM1296040S_lesional_day15855.9876
GSM1296036T_lesional_day15610.0570
GSM1296048V_lesional_day151829.4888
GSM1296059A_lesional_day431481.0985
GSM1296066G_lesional_day431390.8984
GSM1296060R_lesional_day431386.5684
GSM1296063U_lesional_day431565.5386
GSM1296064E_lesional_day432019.2488
GSM1296067H_lesional_day43739.1574
GSM1296062M_lesional_day43630.0771
GSM1296068Q_lesional_day43861.8777
GSM1296050C_lesional_day43881.8877
GSM1296057D_lesional_day432254.5891
GSM1296052I_lesional_day43498.368
GSM1296054J_lesional_day43736.6774
GSM1296049K_lesional_day43578.4570
GSM1296055W_lesional_day431157.8182
GSM1296053X_lesional_day43500.767
GSM1296058Z_lesional_day431722.787
GSM1296051F_lesional_day431100.5380
GSM1296056O_lesional_day432324.9190
GSM1296065S_lesional_day432021.4290
GSM1296061T_lesional_day43641.3671
GSM1296095A_non-lesional_pre-dose1679.8487
GSM1296120B_non-lesional_pre-dose1407.8685
GSM1296077C_non-lesional_pre-dose642.0772
GSM1296093D_non-lesional_pre-dose527.1668
GSM1296104E_non-lesional_pre-dose1773.8987
GSM1296079F_non-lesional_pre-dose751.5874
GSM1296108G_non-lesional_pre-dose1205.9682
GSM1296110H_non-lesional_pre-dose839.3676
GSM1296081I_non-lesional_pre-dose413.2865
GSM1296091J_non-lesional_pre-dose1561.985
GSM1296075K_non-lesional_pre-dose999.4879
GSM1296112L_non-lesional_pre-dose1125.3782
GSM1296100M_non-lesional_pre-dose1663.9487
GSM1296087O_non-lesional_pre-dose685.7873
GSM1296118P_non-lesional_pre-dose1361.1984
GSM1296114Q_non-lesional_pre-dose1135.6982
GSM1296097R_non-lesional_pre-dose1359.6384
GSM1296106S_non-lesional_pre-dose1195.4482
GSM1296102U_non-lesional_pre-dose792.0975
GSM1296122V_non-lesional_pre-dose922.9778
GSM1296089W_non-lesional_pre-dose932.2378
GSM1296083X_non-lesional_pre-dose477.9667
GSM1296116Y_non-lesional_pre-dose1042.6480
GSM1296085Z_non-lesional_pre-dose956.3978