ProfileGDS5420 / 212715_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 74% 68% 64% 69% 71% 66% 70% 69% 75% 67% 65% 67% 73% 67% 67% 72% 69% 76% 76% 74% 70% 69% 66% 65% 72% 76% 70% 77% 71% 64% 88% 65% 72% 71% 78% 69% 73% 72% 84% 73% 74% 71% 83% 73% 81% 80% 83% 77% 79% 78% 67% 75% 73% 75% 70% 73% 71% 74% 70% 66% 81% 81% 77% 76% 85% 81% 80% 81% 79% 83% 80% 69% 73% 73% 79% 74% 73% 80% 83% 75% 80% 77% 76% 79% 75% 73% 76% 85% 77% 76% 77% 75% 78% 80% 82% 77% 82% 76% 81% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose759.7874
GSM1296119B_lesional_pre-dose491.4768
GSM1296076C_lesional_pre-dose378.9764
GSM1296092D_lesional_pre-dose513.2769
GSM1296103E_lesional_pre-dose600.1871
GSM1296078F_lesional_pre-dose422.5366
GSM1296107G_lesional_pre-dose560.2570
GSM1296109H_lesional_pre-dose538.4669
GSM1296080I_lesional_pre-dose797.2175
GSM1296090J_lesional_pre-dose481.0467
GSM1296074K_lesional_pre-dose400.2865
GSM1296111L_lesional_pre-dose483.4267
GSM1296099M_lesional_pre-dose714.3773
GSM1296086O_lesional_pre-dose479.4267
GSM1296117P_lesional_pre-dose480.9367
GSM1296113Q_lesional_pre-dose659.5972
GSM1296096R_lesional_pre-dose531.1769
GSM1296105S_lesional_pre-dose818.5676
GSM1296098T_lesional_pre-dose804.5576
GSM1296101U_lesional_pre-dose722.9474
GSM1296121V_lesional_pre-dose580.3370
GSM1296088W_lesional_pre-dose551.4769
GSM1296082X_lesional_pre-dose416.8266
GSM1296115Y_lesional_pre-dose423.4265
GSM1296084Z_lesional_pre-dose653.1672
GSM1296072B_lesional_day8799.176
GSM1296069L_lesional_day8590.2570
GSM1296071P_lesional_day8850.5177
GSM1296070Y_lesional_day8622.1771
GSM1296073V_lesional_day8402.2264
GSM1296034A_lesional_day151787.688
GSM1296041G_lesional_day15412.865
GSM1296035R_lesional_day15659.9472
GSM1296038U_lesional_day15605.8371
GSM1296047B_lesional_day15910.4278
GSM1296039E_lesional_day15524.1969
GSM1296042H_lesional_day15676.2373
GSM1296043L_lesional_day15661.7572
GSM1296037M_lesional_day151328.9284
GSM1296046P_lesional_day15697.7373
GSM1296044Q_lesional_day15734.7574
GSM1296045Y_lesional_day15625.6971
GSM1296025C_lesional_day151325.183
GSM1296033D_lesional_day15713.8773
GSM1296027I_lesional_day151156.9181
GSM1296032J_lesional_day151081.2280
GSM1296024K_lesional_day151271.1183
GSM1296031W_lesional_day15901.5377
GSM1296028X_lesional_day15987.9679
GSM1296029Z_lesional_day15958.4978
GSM1296026F_lesional_day15461.667
GSM1296030O_lesional_day15770.8375
GSM1296040S_lesional_day15683.7973
GSM1296036T_lesional_day15773.5775
GSM1296048V_lesional_day15555.2570
GSM1296059A_lesional_day43672.5773
GSM1296066G_lesional_day43596.7171
GSM1296060R_lesional_day43756.8474
GSM1296063U_lesional_day43550.1570
GSM1296064E_lesional_day43437.6666
GSM1296067H_lesional_day431111.6881
GSM1296062M_lesional_day431105.9381
GSM1296068Q_lesional_day43841.7477
GSM1296050C_lesional_day43817.4976
GSM1296057D_lesional_day431451.5785
GSM1296052I_lesional_day431198.5381
GSM1296054J_lesional_day431053.0580
GSM1296049K_lesional_day431147.2481
GSM1296055W_lesional_day431014.3279
GSM1296053X_lesional_day431281.7183
GSM1296058Z_lesional_day431103.1980
GSM1296051F_lesional_day43527.7869
GSM1296056O_lesional_day43671.0773
GSM1296065S_lesional_day4370673
GSM1296061T_lesional_day43985.9379
GSM1296095A_non-lesional_pre-dose733.1774
GSM1296120B_non-lesional_pre-dose685.1473
GSM1296077C_non-lesional_pre-dose1096.7980
GSM1296093D_non-lesional_pre-dose1299.7183
GSM1296104E_non-lesional_pre-dose778.6875
GSM1296079F_non-lesional_pre-dose1058.0480
GSM1296108G_non-lesional_pre-dose854.7877
GSM1296110H_non-lesional_pre-dose830.0876
GSM1296081I_non-lesional_pre-dose1033.1279
GSM1296091J_non-lesional_pre-dose759.8575
GSM1296075K_non-lesional_pre-dose656.8473
GSM1296112L_non-lesional_pre-dose825.5976
GSM1296100M_non-lesional_pre-dose1479.7885
GSM1296087O_non-lesional_pre-dose901.5977
GSM1296118P_non-lesional_pre-dose814.0876
GSM1296114Q_non-lesional_pre-dose849.7777
GSM1296097R_non-lesional_pre-dose775.2975
GSM1296106S_non-lesional_pre-dose951.9578
GSM1296102U_non-lesional_pre-dose1079.7580
GSM1296122V_non-lesional_pre-dose1159.6482
GSM1296089W_non-lesional_pre-dose865.7377
GSM1296083X_non-lesional_pre-dose1224.7182
GSM1296116Y_non-lesional_pre-dose808.6776
GSM1296085Z_non-lesional_pre-dose1137.8981