ProfileGDS5420 / 212634_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 69% 70% 66% 62% 70% 75% 68% 56% 67% 70% 77% 61% 66% 74% 74% 64% 59% 55% 59% 72% 63% 70% 78% 62% 62% 77% 70% 71% 69% 52% 77% 58% 59% 66% 64% 73% 71% 54% 76% 69% 75% 60% 59% 56% 61% 55% 62% 58% 60% 60% 57% 62% 59% 68% 56% 76% 60% 66% 68% 68% 53% 70% 66% 60% 57% 59% 59% 65% 60% 48% 66% 56% 66% 56% 67% 64% 55% 64% 61% 62% 69% 71% 56% 65% 64% 71% 56% 57% 70% 73% 63% 67% 59% 64% 59% 58% 75% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose307.4659
GSM1296119B_lesional_pre-dose533.8769
GSM1296076C_lesional_pre-dose552.370
GSM1296092D_lesional_pre-dose445.9866
GSM1296103E_lesional_pre-dose352.6562
GSM1296078F_lesional_pre-dose538.2970
GSM1296107G_lesional_pre-dose744.2675
GSM1296109H_lesional_pre-dose529.1468
GSM1296080I_lesional_pre-dose245.4256
GSM1296090J_lesional_pre-dose477.2967
GSM1296074K_lesional_pre-dose554.770
GSM1296111L_lesional_pre-dose866.9477
GSM1296099M_lesional_pre-dose352.6261
GSM1296086O_lesional_pre-dose428.2666
GSM1296117P_lesional_pre-dose733.7574
GSM1296113Q_lesional_pre-dose738.174
GSM1296096R_lesional_pre-dose412.864
GSM1296105S_lesional_pre-dose318.5359
GSM1296098T_lesional_pre-dose234.6855
GSM1296101U_lesional_pre-dose309.8359
GSM1296121V_lesional_pre-dose627.1372
GSM1296088W_lesional_pre-dose373.0963
GSM1296082X_lesional_pre-dose562.3270
GSM1296115Y_lesional_pre-dose927.1878
GSM1296084Z_lesional_pre-dose349.762
GSM1296072B_lesional_day8362.3762
GSM1296069L_lesional_day8865.677
GSM1296071P_lesional_day8578.8570
GSM1296070Y_lesional_day8604.4671
GSM1296073V_lesional_day8516.9769
GSM1296034A_lesional_day15214.3552
GSM1296041G_lesional_day15863.0377
GSM1296035R_lesional_day15284.3558
GSM1296038U_lesional_day15308.0559
GSM1296047B_lesional_day15465.0566
GSM1296039E_lesional_day15385.4264
GSM1296042H_lesional_day15686.7473
GSM1296043L_lesional_day15629.1871
GSM1296037M_lesional_day15235.8154
GSM1296046P_lesional_day15819.4676
GSM1296044Q_lesional_day15558.8569
GSM1296045Y_lesional_day15768.4975
GSM1296025C_lesional_day15302.9860
GSM1296033D_lesional_day15302.7159
GSM1296027I_lesional_day15226.7556
GSM1296032J_lesional_day15350.3361
GSM1296024K_lesional_day15230.9255
GSM1296031W_lesional_day15372.562
GSM1296028X_lesional_day15276.5858
GSM1296029Z_lesional_day15320.4860
GSM1296026F_lesional_day15310.7360
GSM1296030O_lesional_day15243.1857
GSM1296040S_lesional_day15377.6262
GSM1296036T_lesional_day15323.6359
GSM1296048V_lesional_day15499.3868
GSM1296059A_lesional_day43244.5756
GSM1296066G_lesional_day43808.9176
GSM1296060R_lesional_day43322.0960
GSM1296063U_lesional_day43451.7766
GSM1296064E_lesional_day43479.3968
GSM1296067H_lesional_day43533.5168
GSM1296062M_lesional_day43212.6353
GSM1296068Q_lesional_day43586.8370
GSM1296050C_lesional_day43452.7766
GSM1296057D_lesional_day43326.5260
GSM1296052I_lesional_day43255.8557
GSM1296054J_lesional_day43310.3259
GSM1296049K_lesional_day43296.2259
GSM1296055W_lesional_day43430.1765
GSM1296053X_lesional_day43327.2460
GSM1296058Z_lesional_day43141.9248
GSM1296051F_lesional_day43442.8666
GSM1296056O_lesional_day43242.6356
GSM1296065S_lesional_day43457.3966
GSM1296061T_lesional_day43252.2956
GSM1296095A_non-lesional_pre-dose485.4867
GSM1296120B_non-lesional_pre-dose404.3864
GSM1296077C_non-lesional_pre-dose230.3455
GSM1296093D_non-lesional_pre-dose421.7764
GSM1296104E_non-lesional_pre-dose331.8861
GSM1296079F_non-lesional_pre-dose348.8162
GSM1296108G_non-lesional_pre-dose55469
GSM1296110H_non-lesional_pre-dose62771
GSM1296081I_non-lesional_pre-dose238.656
GSM1296091J_non-lesional_pre-dose417.865
GSM1296075K_non-lesional_pre-dose384.6164
GSM1296112L_non-lesional_pre-dose606.4871
GSM1296100M_non-lesional_pre-dose255.7556
GSM1296087O_non-lesional_pre-dose238.2957
GSM1296118P_non-lesional_pre-dose596.970
GSM1296114Q_non-lesional_pre-dose690.3673
GSM1296097R_non-lesional_pre-dose390.2563
GSM1296106S_non-lesional_pre-dose491.4767
GSM1296102U_non-lesional_pre-dose321.5259
GSM1296122V_non-lesional_pre-dose398.3164
GSM1296089W_non-lesional_pre-dose317.4459
GSM1296083X_non-lesional_pre-dose284.9258
GSM1296116Y_non-lesional_pre-dose755.3575
GSM1296085Z_non-lesional_pre-dose274.7258