ProfileGDS5420 / 212484_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 67% 49% 58% 73% 70% 59% 51% 58% 74% 71% 63% 50% 60% 71% 53% 51% 61% 66% 62% 67% 49% 72% 70% 51% 71% 58% 47% 56% 50% 51% 66% 53% 64% 68% 56% 55% 56% 55% 63% 54% 56% 51% 59% 74% 74% 72% 62% 72% 72% 75% 64% 77% 64% 66% 51% 68% 54% 61% 61% 61% 60% 66% 52% 58% 64% 73% 75% 63% 61% 72% 67% 62% 63% 58% 65% 64% 54% 59% 73% 58% 63% 55% 56% 72% 76% 61% 56% 62% 74% 52% 51% 58% 60% 63% 50% 75% 70% 52% 70% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose496.6167
GSM1296119B_lesional_pre-dose170.9249
GSM1296076C_lesional_pre-dose255.8658
GSM1296092D_lesional_pre-dose707.0873
GSM1296103E_lesional_pre-dose568.2170
GSM1296078F_lesional_pre-dose271.3159
GSM1296107G_lesional_pre-dose19651
GSM1296109H_lesional_pre-dose303.0658
GSM1296080I_lesional_pre-dose731.1674
GSM1296090J_lesional_pre-dose603.3371
GSM1296074K_lesional_pre-dose352.1263
GSM1296111L_lesional_pre-dose181.2750
GSM1296099M_lesional_pre-dose324.3660
GSM1296086O_lesional_pre-dose590.8771
GSM1296117P_lesional_pre-dose223.6753
GSM1296113Q_lesional_pre-dose20451
GSM1296096R_lesional_pre-dose331.7461
GSM1296105S_lesional_pre-dose467.4366
GSM1296098T_lesional_pre-dose358.9462
GSM1296101U_lesional_pre-dose494.3867
GSM1296121V_lesional_pre-dose166.4249
GSM1296088W_lesional_pre-dose667.2472
GSM1296082X_lesional_pre-dose545.8270
GSM1296115Y_lesional_pre-dose186.951
GSM1296084Z_lesional_pre-dose598.4171
GSM1296072B_lesional_day8288.6558
GSM1296069L_lesional_day8165.7647
GSM1296071P_lesional_day8277.4156
GSM1296070Y_lesional_day8192.9450
GSM1296073V_lesional_day8180.5151
GSM1296034A_lesional_day15471.5266
GSM1296041G_lesional_day15208.4953
GSM1296035R_lesional_day15402.9764
GSM1296038U_lesional_day15494.7368
GSM1296047B_lesional_day15270.3156
GSM1296039E_lesional_day15225.4255
GSM1296042H_lesional_day15269.3456
GSM1296043L_lesional_day15259.7355
GSM1296037M_lesional_day15390.4463
GSM1296046P_lesional_day15243.5854
GSM1296044Q_lesional_day15265.7356
GSM1296045Y_lesional_day15209.9351
GSM1296025C_lesional_day15285.6959
GSM1296033D_lesional_day15735.2274
GSM1296027I_lesional_day15714.1474
GSM1296032J_lesional_day15663.3972
GSM1296024K_lesional_day15350.862
GSM1296031W_lesional_day15673.6272
GSM1296028X_lesional_day15647.7872
GSM1296029Z_lesional_day15781.9875
GSM1296026F_lesional_day15387.2164
GSM1296030O_lesional_day15869.8877
GSM1296040S_lesional_day15413.4564
GSM1296036T_lesional_day15475.9266
GSM1296048V_lesional_day15190.9651
GSM1296059A_lesional_day43509.868
GSM1296066G_lesional_day43228.8954
GSM1296060R_lesional_day43338.4761
GSM1296063U_lesional_day43329.6161
GSM1296064E_lesional_day43329.5861
GSM1296067H_lesional_day43342.6560
GSM1296062M_lesional_day43471.7566
GSM1296068Q_lesional_day43220.4952
GSM1296050C_lesional_day43282.8158
GSM1296057D_lesional_day43400.7564
GSM1296052I_lesional_day43672.8673
GSM1296054J_lesional_day43784.875
GSM1296049K_lesional_day43366.5663
GSM1296055W_lesional_day43350.3661
GSM1296053X_lesional_day43669.9472
GSM1296058Z_lesional_day43471.3367
GSM1296051F_lesional_day43345.5362
GSM1296056O_lesional_day43373.5863
GSM1296065S_lesional_day43293.5758
GSM1296061T_lesional_day43451.8565
GSM1296095A_non-lesional_pre-dose386.0264
GSM1296120B_non-lesional_pre-dose240.6554
GSM1296077C_non-lesional_pre-dose288.7359
GSM1296093D_non-lesional_pre-dose722.5473
GSM1296104E_non-lesional_pre-dose274.0458
GSM1296079F_non-lesional_pre-dose358.3763
GSM1296108G_non-lesional_pre-dose252.1355
GSM1296110H_non-lesional_pre-dose271.2356
GSM1296081I_non-lesional_pre-dose645.1572
GSM1296091J_non-lesional_pre-dose835.3176
GSM1296075K_non-lesional_pre-dose323.1561
GSM1296112L_non-lesional_pre-dose272.556
GSM1296100M_non-lesional_pre-dose362.2462
GSM1296087O_non-lesional_pre-dose710.774
GSM1296118P_non-lesional_pre-dose221.252
GSM1296114Q_non-lesional_pre-dose200.451
GSM1296097R_non-lesional_pre-dose284.8458
GSM1296106S_non-lesional_pre-dose339.0960
GSM1296102U_non-lesional_pre-dose407.9663
GSM1296122V_non-lesional_pre-dose183.6450
GSM1296089W_non-lesional_pre-dose791.3375
GSM1296083X_non-lesional_pre-dose585.5570
GSM1296116Y_non-lesional_pre-dose217.2952
GSM1296085Z_non-lesional_pre-dose596.7970