ProfileGDS5420 / 212445_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 52% 62% 61% 58% 56% 56% 56% 48% 62% 61% 59% 51% 59% 61% 46% 46% 60% 65% 44% 46% 54% 62% 56% 50% 60% 61% 54% 55% 56% 48% 57% 48% 59% 58% 63% 56% 49% 57% 70% 56% 49% 60% 65% 65% 71% 74% 59% 57% 67% 63% 53% 62% 54% 48% 50% 57% 50% 62% 60% 63% 54% 61% 54% 73% 70% 68% 63% 59% 63% 63% 66% 62% 60% 66% 47% 61% 68% 65% 70% 71% 67% 55% 55% 74% 73% 60% 59% 79% 72% 72% 55% 66% 63% 57% 61% 59% 65% 65% 77% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose200.3452
GSM1296119B_lesional_pre-dose366.4162
GSM1296076C_lesional_pre-dose312.861
GSM1296092D_lesional_pre-dose251.2358
GSM1296103E_lesional_pre-dose239.9856
GSM1296078F_lesional_pre-dose224.8556
GSM1296107G_lesional_pre-dose252.3256
GSM1296109H_lesional_pre-dose164.2848
GSM1296080I_lesional_pre-dose343.0762
GSM1296090J_lesional_pre-dose311.9661
GSM1296074K_lesional_pre-dose258.8659
GSM1296111L_lesional_pre-dose197.8851
GSM1296099M_lesional_pre-dose307.1459
GSM1296086O_lesional_pre-dose319.6861
GSM1296117P_lesional_pre-dose151.0546
GSM1296113Q_lesional_pre-dose154.6646
GSM1296096R_lesional_pre-dose310.8660
GSM1296105S_lesional_pre-dose427.2865
GSM1296098T_lesional_pre-dose122.6744
GSM1296101U_lesional_pre-dose142.4346
GSM1296121V_lesional_pre-dose231.6854
GSM1296088W_lesional_pre-dose356.2162
GSM1296082X_lesional_pre-dose232.5856
GSM1296115Y_lesional_pre-dose179.8950
GSM1296084Z_lesional_pre-dose309.5260
GSM1296072B_lesional_day8352.3661
GSM1296069L_lesional_day8245.3654
GSM1296071P_lesional_day8262.3655
GSM1296070Y_lesional_day8263.7956
GSM1296073V_lesional_day8154.3448
GSM1296034A_lesional_day15289.2657
GSM1296041G_lesional_day15158.0348
GSM1296035R_lesional_day15311.259
GSM1296038U_lesional_day15280.3858
GSM1296047B_lesional_day15397.8263
GSM1296039E_lesional_day15245.2456
GSM1296042H_lesional_day15179.1649
GSM1296043L_lesional_day15286.757
GSM1296037M_lesional_day15579.3670
GSM1296046P_lesional_day15263.8256
GSM1296044Q_lesional_day15188.7549
GSM1296045Y_lesional_day15333.560
GSM1296025C_lesional_day15416.8765
GSM1296033D_lesional_day15424.4865
GSM1296027I_lesional_day15595.1271
GSM1296032J_lesional_day15745.0974
GSM1296024K_lesional_day15293.6559
GSM1296031W_lesional_day15286.5657
GSM1296028X_lesional_day15476.2167
GSM1296029Z_lesional_day15388.663
GSM1296026F_lesional_day15195.0353
GSM1296030O_lesional_day15345.0762
GSM1296040S_lesional_day15219.1254
GSM1296036T_lesional_day15164.8848
GSM1296048V_lesional_day15178.6350
GSM1296059A_lesional_day43263.1957
GSM1296066G_lesional_day43182.5950
GSM1296060R_lesional_day43368.7462
GSM1296063U_lesional_day43309.4860
GSM1296064E_lesional_day43363.7463
GSM1296067H_lesional_day43240.2154
GSM1296062M_lesional_day43358.6161
GSM1296068Q_lesional_day43252.1254
GSM1296050C_lesional_day43659.4773
GSM1296057D_lesional_day43601.3270
GSM1296052I_lesional_day43511.2468
GSM1296054J_lesional_day43404.2663
GSM1296049K_lesional_day43297.2859
GSM1296055W_lesional_day43383.1263
GSM1296053X_lesional_day43394.8663
GSM1296058Z_lesional_day43444.6666
GSM1296051F_lesional_day43342.1862
GSM1296056O_lesional_day43307.5860
GSM1296065S_lesional_day43470.2766
GSM1296061T_lesional_day43150.2947
GSM1296095A_non-lesional_pre-dose336.7361
GSM1296120B_non-lesional_pre-dose498.1468
GSM1296077C_non-lesional_pre-dose414.8665
GSM1296093D_non-lesional_pre-dose604.1570
GSM1296104E_non-lesional_pre-dose607.5971
GSM1296079F_non-lesional_pre-dose477.9867
GSM1296108G_non-lesional_pre-dose251.9755
GSM1296110H_non-lesional_pre-dose262.1555
GSM1296081I_non-lesional_pre-dose725.2974
GSM1296091J_non-lesional_pre-dose674.2673
GSM1296075K_non-lesional_pre-dose288.8660
GSM1296112L_non-lesional_pre-dose329.859
GSM1296100M_non-lesional_pre-dose991.4279
GSM1296087O_non-lesional_pre-dose661.7272
GSM1296118P_non-lesional_pre-dose650.3772
GSM1296114Q_non-lesional_pre-dose255.0455
GSM1296097R_non-lesional_pre-dose444.6666
GSM1296106S_non-lesional_pre-dose395.4163
GSM1296102U_non-lesional_pre-dose280.8557
GSM1296122V_non-lesional_pre-dose338.9161
GSM1296089W_non-lesional_pre-dose311.5859
GSM1296083X_non-lesional_pre-dose441.9365
GSM1296116Y_non-lesional_pre-dose438.8865
GSM1296085Z_non-lesional_pre-dose904.0677