ProfileGDS5420 / 212153_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 95% 92% 91% 91% 89% 87% 92% 89% 93% 89% 91% 89% 90% 87% 91% 93% 87% 94% 94% 93% 93% 90% 86% 90% 92% 95% 90% 95% 92% 91% 98% 90% 92% 89% 95% 89% 93% 91% 93% 94% 95% 93% 97% 93% 93% 95% 96% 93% 92% 94% 89% 91% 89% 94% 93% 90% 92% 93% 89% 88% 96% 95% 95% 94% 94% 94% 97% 98% 92% 94% 94% 89% 89% 93% 96% 91% 95% 93% 96% 89% 95% 94% 95% 94% 94% 94% 94% 93% 92% 96% 95% 91% 93% 96% 96% 93% 93% 93% 94% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose3263.6195
GSM1296119B_lesional_pre-dose2634.7892
GSM1296076C_lesional_pre-dose2558.3991
GSM1296092D_lesional_pre-dose2405.6391
GSM1296103E_lesional_pre-dose1948.7889
GSM1296078F_lesional_pre-dose1792.0787
GSM1296107G_lesional_pre-dose2505.2292
GSM1296109H_lesional_pre-dose1935.1189
GSM1296080I_lesional_pre-dose2819.9193
GSM1296090J_lesional_pre-dose2007.3689
GSM1296074K_lesional_pre-dose2719.5691
GSM1296111L_lesional_pre-dose1986.9289
GSM1296099M_lesional_pre-dose2140.5790
GSM1296086O_lesional_pre-dose1732.8387
GSM1296117P_lesional_pre-dose2229.9391
GSM1296113Q_lesional_pre-dose2635.8193
GSM1296096R_lesional_pre-dose1737.0387
GSM1296105S_lesional_pre-dose2817.9494
GSM1296098T_lesional_pre-dose2970.3194
GSM1296101U_lesional_pre-dose2716.4993
GSM1296121V_lesional_pre-dose2755.7493
GSM1296088W_lesional_pre-dose2109.990
GSM1296082X_lesional_pre-dose1722.4986
GSM1296115Y_lesional_pre-dose2146.5790
GSM1296084Z_lesional_pre-dose2599.0792
GSM1296072B_lesional_day83533.4995
GSM1296069L_lesional_day82082.0690
GSM1296071P_lesional_day82968.9995
GSM1296070Y_lesional_day82398.4692
GSM1296073V_lesional_day82499.1691
GSM1296034A_lesional_day155003.5998
GSM1296041G_lesional_day152244.2990
GSM1296035R_lesional_day152644.8492
GSM1296038U_lesional_day152050.9389
GSM1296047B_lesional_day153284.4795
GSM1296039E_lesional_day152141.8189
GSM1296042H_lesional_day152651.4793
GSM1296043L_lesional_day152259.6291
GSM1296037M_lesional_day152894.7493
GSM1296046P_lesional_day152894.2594
GSM1296044Q_lesional_day153090.0995
GSM1296045Y_lesional_day152645.0593
GSM1296025C_lesional_day154480.2697
GSM1296033D_lesional_day152742.7793
GSM1296027I_lesional_day153003.1993
GSM1296032J_lesional_day153305.8595
GSM1296024K_lesional_day153857.1596
GSM1296031W_lesional_day152691.4593
GSM1296028X_lesional_day15242492
GSM1296029Z_lesional_day152899.8694
GSM1296026F_lesional_day152102.5289
GSM1296030O_lesional_day152395.4791
GSM1296040S_lesional_day151925.2389
GSM1296036T_lesional_day153056.1694
GSM1296048V_lesional_day152840.3393
GSM1296059A_lesional_day432107.6790
GSM1296066G_lesional_day432394.7592
GSM1296060R_lesional_day432770.2893
GSM1296063U_lesional_day432048.9789
GSM1296064E_lesional_day431876.2288
GSM1296067H_lesional_day433393.596
GSM1296062M_lesional_day433368.1695
GSM1296068Q_lesional_day433172.1395
GSM1296050C_lesional_day433337.8894
GSM1296057D_lesional_day432935.7694
GSM1296052I_lesional_day433043.894
GSM1296054J_lesional_day434208.5197
GSM1296049K_lesional_day435049.5298
GSM1296055W_lesional_day432506.0292
GSM1296053X_lesional_day432987.5294
GSM1296058Z_lesional_day432932.8194
GSM1296051F_lesional_day432114.8689
GSM1296056O_lesional_day432122.4589
GSM1296065S_lesional_day432593.3293
GSM1296061T_lesional_day433961.7796
GSM1296095A_non-lesional_pre-dose2493.7991
GSM1296120B_non-lesional_pre-dose3220.9895
GSM1296077C_non-lesional_pre-dose2851.7593
GSM1296093D_non-lesional_pre-dose3467.8496
GSM1296104E_non-lesional_pre-dose2118.5589
GSM1296079F_non-lesional_pre-dose3629.8695
GSM1296108G_non-lesional_pre-dose3094.1394
GSM1296110H_non-lesional_pre-dose3068.4695
GSM1296081I_non-lesional_pre-dose3168.9494
GSM1296091J_non-lesional_pre-dose3027.794
GSM1296075K_non-lesional_pre-dose3095.4994
GSM1296112L_non-lesional_pre-dose2703.3594
GSM1296100M_non-lesional_pre-dose2650.3393
GSM1296087O_non-lesional_pre-dose2791.5992
GSM1296118P_non-lesional_pre-dose3279.9196
GSM1296114Q_non-lesional_pre-dose3410.6295
GSM1296097R_non-lesional_pre-dose2401.2491
GSM1296106S_non-lesional_pre-dose2633.9893
GSM1296102U_non-lesional_pre-dose3527.5596
GSM1296122V_non-lesional_pre-dose3766.4496
GSM1296089W_non-lesional_pre-dose2571.3393
GSM1296083X_non-lesional_pre-dose2841.1393
GSM1296116Y_non-lesional_pre-dose2629.9793
GSM1296085Z_non-lesional_pre-dose3000.0994