ProfileGDS5420 / 211862_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 69% 70% 66% 62% 68% 60% 72% 71% 52% 66% 67% 71% 67% 60% 73% 77% 71% 65% 70% 69% 74% 60% 67% 75% 59% 68% 69% 66% 71% 73% 65% 75% 70% 68% 66% 74% 73% 69% 59% 70% 74% 67% 51% 54% 50% 52% 52% 59% 50% 55% 48% 52% 66% 68% 70% 64% 70% 67% 69% 74% 68% 64% 71% 60% 62% 55% 56% 57% 68% 55% 63% 58% 71% 67% 68% 67% 71% 48% 60% 67% 56% 70% 71% 56% 54% 57% 71% 63% 44% 68% 79% 63% 69% 66% 70% 54% 58% 69% 54% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose554.5469
GSM1296119B_lesional_pre-dose577.1370
GSM1296076C_lesional_pre-dose422.0666
GSM1296092D_lesional_pre-dose325.6462
GSM1296103E_lesional_pre-dose512.0168
GSM1296078F_lesional_pre-dose281.8960
GSM1296107G_lesional_pre-dose650.8472
GSM1296109H_lesional_pre-dose631.6371
GSM1296080I_lesional_pre-dose18852
GSM1296090J_lesional_pre-dose428.3666
GSM1296074K_lesional_pre-dose442.9567
GSM1296111L_lesional_pre-dose596.4871
GSM1296099M_lesional_pre-dose489.9267
GSM1296086O_lesional_pre-dose300.9460
GSM1296117P_lesional_pre-dose689.3373
GSM1296113Q_lesional_pre-dose845.8677
GSM1296096R_lesional_pre-dose62471
GSM1296105S_lesional_pre-dose431.4165
GSM1296098T_lesional_pre-dose576.3770
GSM1296101U_lesional_pre-dose551.3269
GSM1296121V_lesional_pre-dose741.3574
GSM1296088W_lesional_pre-dose303.4560
GSM1296082X_lesional_pre-dose448.967
GSM1296115Y_lesional_pre-dose787.1575
GSM1296084Z_lesional_pre-dose293.2159
GSM1296072B_lesional_day8521.1568
GSM1296069L_lesional_day8559.3269
GSM1296071P_lesional_day8480.266
GSM1296070Y_lesional_day8601.4671
GSM1296073V_lesional_day8665.8973
GSM1296034A_lesional_day15447.1465
GSM1296041G_lesional_day15783.5475
GSM1296035R_lesional_day15574.2270
GSM1296038U_lesional_day15494.0668
GSM1296047B_lesional_day15453.1366
GSM1296039E_lesional_day15696.2974
GSM1296042H_lesional_day15700.5173
GSM1296043L_lesional_day15548.2769
GSM1296037M_lesional_day15304.0759
GSM1296046P_lesional_day15580.8970
GSM1296044Q_lesional_day15722.4974
GSM1296045Y_lesional_day15499.5967
GSM1296025C_lesional_day15179.5851
GSM1296033D_lesional_day1522654
GSM1296027I_lesional_day15156.6350
GSM1296032J_lesional_day15194.7252
GSM1296024K_lesional_day15185.3352
GSM1296031W_lesional_day15316.2959
GSM1296028X_lesional_day15174.0250
GSM1296029Z_lesional_day15236.3355
GSM1296026F_lesional_day15144.1248
GSM1296030O_lesional_day15173.6252
GSM1296040S_lesional_day1546166
GSM1296036T_lesional_day15533.9268
GSM1296048V_lesional_day15561.4870
GSM1296059A_lesional_day43399.464
GSM1296066G_lesional_day43580.3570
GSM1296060R_lesional_day43494.9267
GSM1296063U_lesional_day43543.4169
GSM1296064E_lesional_day43718.5874
GSM1296067H_lesional_day43526.3168
GSM1296062M_lesional_day43411.7464
GSM1296068Q_lesional_day43626.7271
GSM1296050C_lesional_day43301.9460
GSM1296057D_lesional_day43364.1962
GSM1296052I_lesional_day43213.2555
GSM1296054J_lesional_day43261.9656
GSM1296049K_lesional_day43258.6157
GSM1296055W_lesional_day43530.1168
GSM1296053X_lesional_day43230.8755
GSM1296058Z_lesional_day43380.3863
GSM1296051F_lesional_day43266.1758
GSM1296056O_lesional_day43587.5671
GSM1296065S_lesional_day43489.8967
GSM1296061T_lesional_day43517.9968
GSM1296095A_non-lesional_pre-dose481.8967
GSM1296120B_non-lesional_pre-dose624.271
GSM1296077C_non-lesional_pre-dose140.9748
GSM1296093D_non-lesional_pre-dose338.9160
GSM1296104E_non-lesional_pre-dose477.5567
GSM1296079F_non-lesional_pre-dose234.0256
GSM1296108G_non-lesional_pre-dose589.2170
GSM1296110H_non-lesional_pre-dose621.4771
GSM1296081I_non-lesional_pre-dose237.4156
GSM1296091J_non-lesional_pre-dose212.3154
GSM1296075K_non-lesional_pre-dose245.7557
GSM1296112L_non-lesional_pre-dose618.2671
GSM1296100M_non-lesional_pre-dose404.7663
GSM1296087O_non-lesional_pre-dose104.944
GSM1296118P_non-lesional_pre-dose510.8968
GSM1296114Q_non-lesional_pre-dose955.6679
GSM1296097R_non-lesional_pre-dose384.7363
GSM1296106S_non-lesional_pre-dose553.469
GSM1296102U_non-lesional_pre-dose472.0766
GSM1296122V_non-lesional_pre-dose577.2370
GSM1296089W_non-lesional_pre-dose239.8254
GSM1296083X_non-lesional_pre-dose278.5958
GSM1296116Y_non-lesional_pre-dose547.7769
GSM1296085Z_non-lesional_pre-dose213.9254