ProfileGDS5420 / 211356_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 25% 48% 41% 38% 21% 39% 50% 38% 35% 37% 24% 40% 35% 32% 46% 60% 30% 34% 31% 15% 38% 31% 44% 50% 24% 41% 35% 54% 57% 36% 35% 41% 27% 27% 31% 37% 50% 36% 31% 55% 63% 57% 42% 38% 45% 46% 35% 42% 40% 32% 39% 20% 6% 30% 33% 33% 50% 27% 38% 36% 44% 33% 60% 49% 37% 48% 36% 38% 35% 36% 35% 35% 19% 34% 39% 45% 44% 47% 30% 37% 43% 60% 57% 48% 39% 43% 52% 12% 32% 45% 68% 33% 29% 33% 39% 45% 40% 60% 34% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose33.525
GSM1296119B_lesional_pre-dose158.1848
GSM1296076C_lesional_pre-dose89.9341
GSM1296092D_lesional_pre-dose70.7138
GSM1296103E_lesional_pre-dose23.2721
GSM1296078F_lesional_pre-dose80.5139
GSM1296107G_lesional_pre-dose184.6950
GSM1296109H_lesional_pre-dose90.2538
GSM1296080I_lesional_pre-dose60.2935
GSM1296090J_lesional_pre-dose71.2237
GSM1296074K_lesional_pre-dose28.1624
GSM1296111L_lesional_pre-dose106.7440
GSM1296099M_lesional_pre-dose65.7135
GSM1296086O_lesional_pre-dose50.0732
GSM1296117P_lesional_pre-dose148.4746
GSM1296113Q_lesional_pre-dose329.8360
GSM1296096R_lesional_pre-dose44.2130
GSM1296105S_lesional_pre-dose66.9334
GSM1296098T_lesional_pre-dose57.1931
GSM1296101U_lesional_pre-dose16.2215
GSM1296121V_lesional_pre-dose86.5538
GSM1296088W_lesional_pre-dose46.8431
GSM1296082X_lesional_pre-dose106.1944
GSM1296115Y_lesional_pre-dose177.1950
GSM1296084Z_lesional_pre-dose33.1224
GSM1296072B_lesional_day8108.8441
GSM1296069L_lesional_day884.7535
GSM1296071P_lesional_day8242.5154
GSM1296070Y_lesional_day8284.2657
GSM1296073V_lesional_day875.6636
GSM1296034A_lesional_day1569.8435
GSM1296041G_lesional_day15105.7241
GSM1296035R_lesional_day1534.1227
GSM1296038U_lesional_day1537.8427
GSM1296047B_lesional_day1562.4831
GSM1296039E_lesional_day1571.9537
GSM1296042H_lesional_day15191.0250
GSM1296043L_lesional_day1584.9936
GSM1296037M_lesional_day1555.0831
GSM1296046P_lesional_day15257.9355
GSM1296044Q_lesional_day15398.1263
GSM1296045Y_lesional_day15286.7557
GSM1296025C_lesional_day15101.4942
GSM1296033D_lesional_day1576.6438
GSM1296027I_lesional_day15107.6145
GSM1296032J_lesional_day15133.9646
GSM1296024K_lesional_day1562.8535
GSM1296031W_lesional_day15113.3142
GSM1296028X_lesional_day1590.2940
GSM1296029Z_lesional_day1552.7932
GSM1296026F_lesional_day1583.6139
GSM1296030O_lesional_day1518.7120
GSM1296040S_lesional_day156.556
GSM1296036T_lesional_day1551.7730
GSM1296048V_lesional_day1565.2633
GSM1296059A_lesional_day4353.4833
GSM1296066G_lesional_day43185.4550
GSM1296060R_lesional_day4336.4527
GSM1296063U_lesional_day4381.7138
GSM1296064E_lesional_day4367.2736
GSM1296067H_lesional_day43136.8744
GSM1296062M_lesional_day4355.3733
GSM1296068Q_lesional_day43339.2560
GSM1296050C_lesional_day43162.7849
GSM1296057D_lesional_day4374.9737
GSM1296052I_lesional_day43138.6548
GSM1296054J_lesional_day4372.2436
GSM1296049K_lesional_day4380.9638
GSM1296055W_lesional_day4371.3635
GSM1296053X_lesional_day4368.2636
GSM1296058Z_lesional_day4360.7235
GSM1296051F_lesional_day4365.2235
GSM1296056O_lesional_day4319.8719
GSM1296065S_lesional_day4364.5734
GSM1296061T_lesional_day4390.939
GSM1296095A_non-lesional_pre-dose119.5545
GSM1296120B_non-lesional_pre-dose133.544
GSM1296077C_non-lesional_pre-dose138.1447
GSM1296093D_non-lesional_pre-dose50.4430
GSM1296104E_non-lesional_pre-dose74.7437
GSM1296079F_non-lesional_pre-dose106.743
GSM1296108G_non-lesional_pre-dose33160
GSM1296110H_non-lesional_pre-dose292.8157
GSM1296081I_non-lesional_pre-dose141.7548
GSM1296091J_non-lesional_pre-dose82.1539
GSM1296075K_non-lesional_pre-dose101.3543
GSM1296112L_non-lesional_pre-dose218.5952
GSM1296100M_non-lesional_pre-dose12.6112
GSM1296087O_non-lesional_pre-dose46.2732
GSM1296118P_non-lesional_pre-dose150.9645
GSM1296114Q_non-lesional_pre-dose525.4368
GSM1296097R_non-lesional_pre-dose55.133
GSM1296106S_non-lesional_pre-dose47.9829
GSM1296102U_non-lesional_pre-dose61.1333
GSM1296122V_non-lesional_pre-dose98.339
GSM1296089W_non-lesional_pre-dose133.8845
GSM1296083X_non-lesional_pre-dose90.6540
GSM1296116Y_non-lesional_pre-dose344.9760
GSM1296085Z_non-lesional_pre-dose62.5934