ProfileGDS5420 / 210812_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 44% 33% 31% 34% 43% 39% 34% 39% 44% 35% 40% 32% 41% 37% 32% 37% 38% 37% 45% 34% 37% 43% 46% 28% 37% 35% 32% 36% 24% 38% 30% 35% 43% 31% 40% 34% 29% 29% 33% 27% 38% 30% 45% 33% 27% 34% 42% 30% 39% 31% 38% 36% 31% 39% 38% 36% 32% 44% 28% 43% 30% 37% 31% 33% 38% 32% 33% 45% 31% 32% 39% 33% 46% 34% 37% 33% 35% 31% 40% 39% 37% 35% 35% 32% 37% 33% 32% 30% 37% 35% 33% 40% 35% 35% 31% 35% 43% 33% 32% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose117.6244
GSM1296119B_lesional_pre-dose63.3133
GSM1296076C_lesional_pre-dose52.2231
GSM1296092D_lesional_pre-dose53.8234
GSM1296103E_lesional_pre-dose107.8943
GSM1296078F_lesional_pre-dose8239
GSM1296107G_lesional_pre-dose71.7334
GSM1296109H_lesional_pre-dose9939
GSM1296080I_lesional_pre-dose103.3744
GSM1296090J_lesional_pre-dose60.0235
GSM1296074K_lesional_pre-dose76.9340
GSM1296111L_lesional_pre-dose63.432
GSM1296099M_lesional_pre-dose98.0241
GSM1296086O_lesional_pre-dose70.2237
GSM1296117P_lesional_pre-dose65.6832
GSM1296113Q_lesional_pre-dose96.0637
GSM1296096R_lesional_pre-dose76.0538
GSM1296105S_lesional_pre-dose77.7637
GSM1296098T_lesional_pre-dose128.445
GSM1296101U_lesional_pre-dose63.3734
GSM1296121V_lesional_pre-dose81.1337
GSM1296088W_lesional_pre-dose105.9843
GSM1296082X_lesional_pre-dose116.846
GSM1296115Y_lesional_pre-dose46.9428
GSM1296084Z_lesional_pre-dose75.7537
GSM1296072B_lesional_day871.735
GSM1296069L_lesional_day869.6732
GSM1296071P_lesional_day885.9436
GSM1296070Y_lesional_day840.124
GSM1296073V_lesional_day884.4238
GSM1296034A_lesional_day1552.0730
GSM1296041G_lesional_day1573.6535
GSM1296035R_lesional_day15107.4743
GSM1296038U_lesional_day1548.631
GSM1296047B_lesional_day15101.6640
GSM1296039E_lesional_day1562.2834
GSM1296042H_lesional_day1553.6629
GSM1296043L_lesional_day1554.5729
GSM1296037M_lesional_day156233
GSM1296046P_lesional_day1548.927
GSM1296044Q_lesional_day1598.7638
GSM1296045Y_lesional_day1561.5630
GSM1296025C_lesional_day15123.1945
GSM1296033D_lesional_day1556.8333
GSM1296027I_lesional_day1531.9927
GSM1296032J_lesional_day1560.2634
GSM1296024K_lesional_day15100.542
GSM1296031W_lesional_day1549.8430
GSM1296028X_lesional_day1583.7139
GSM1296029Z_lesional_day1546.9831
GSM1296026F_lesional_day1578.5838
GSM1296030O_lesional_day1555.836
GSM1296040S_lesional_day1552.1531
GSM1296036T_lesional_day1596.4439
GSM1296048V_lesional_day1588.7638
GSM1296059A_lesional_day4365.9536
GSM1296066G_lesional_day4363.632
GSM1296060R_lesional_day43114.9944
GSM1296063U_lesional_day4343.6528
GSM1296064E_lesional_day43105.4943
GSM1296067H_lesional_day4356.1730
GSM1296062M_lesional_day4373.6137
GSM1296068Q_lesional_day4365.4831
GSM1296050C_lesional_day4360.6433
GSM1296057D_lesional_day4378.7938
GSM1296052I_lesional_day4345.7432
GSM1296054J_lesional_day4359.1833
GSM1296049K_lesional_day43126.9745
GSM1296055W_lesional_day4353.0231
GSM1296053X_lesional_day4355.1532
GSM1296058Z_lesional_day4378.4539
GSM1296051F_lesional_day4355.7233
GSM1296056O_lesional_day43123.8746
GSM1296065S_lesional_day4361.7434
GSM1296061T_lesional_day4376.8337
GSM1296095A_non-lesional_pre-dose54.1333
GSM1296120B_non-lesional_pre-dose76.0935
GSM1296077C_non-lesional_pre-dose46.5831
GSM1296093D_non-lesional_pre-dose95.8340
GSM1296104E_non-lesional_pre-dose87.8139
GSM1296079F_non-lesional_pre-dose73.7937
GSM1296108G_non-lesional_pre-dose74.5635
GSM1296110H_non-lesional_pre-dose80.5235
GSM1296081I_non-lesional_pre-dose45.2632
GSM1296091J_non-lesional_pre-dose69.5937
GSM1296075K_non-lesional_pre-dose55.7733
GSM1296112L_non-lesional_pre-dose7132
GSM1296100M_non-lesional_pre-dose48.9130
GSM1296087O_non-lesional_pre-dose64.9137
GSM1296118P_non-lesional_pre-dose80.5735
GSM1296114Q_non-lesional_pre-dose73.2733
GSM1296097R_non-lesional_pre-dose93.6240
GSM1296106S_non-lesional_pre-dose70.7435
GSM1296102U_non-lesional_pre-dose69.5735
GSM1296122V_non-lesional_pre-dose61.2131
GSM1296089W_non-lesional_pre-dose71.3135
GSM1296083X_non-lesional_pre-dose107.9243
GSM1296116Y_non-lesional_pre-dose76.7333
GSM1296085Z_non-lesional_pre-dose55.5132