ProfileGDS5420 / 210417_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 65% 59% 50% 56% 66% 48% 64% 64% 52% 54% 55% 58% 68% 55% 61% 60% 68% 61% 63% 71% 58% 53% 53% 60% 50% 62% 59% 59% 59% 58% 64% 59% 70% 65% 60% 65% 60% 57% 69% 60% 60% 60% 45% 54% 44% 51% 48% 57% 49% 50% 49% 45% 67% 56% 61% 71% 60% 68% 64% 69% 63% 64% 57% 49% 72% 45% 47% 51% 64% 48% 72% 49% 72% 66% 60% 67% 59% 48% 48% 65% 48% 59% 61% 50% 50% 52% 57% 70% 41% 59% 59% 67% 63% 66% 58% 55% 52% 58% 53% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose435.2565
GSM1296119B_lesional_pre-dose304.0159
GSM1296076C_lesional_pre-dose157.4350
GSM1296092D_lesional_pre-dose224.3956
GSM1296103E_lesional_pre-dose458.6166
GSM1296078F_lesional_pre-dose139.2748
GSM1296107G_lesional_pre-dose396.1164
GSM1296109H_lesional_pre-dose419.5964
GSM1296080I_lesional_pre-dose185.5252
GSM1296090J_lesional_pre-dose203.554
GSM1296074K_lesional_pre-dose204.6455
GSM1296111L_lesional_pre-dose280.7558
GSM1296099M_lesional_pre-dose506.6768
GSM1296086O_lesional_pre-dose220.5355
GSM1296117P_lesional_pre-dose343.9761
GSM1296113Q_lesional_pre-dose342.3760
GSM1296096R_lesional_pre-dose511.5568
GSM1296105S_lesional_pre-dose352.3961
GSM1296098T_lesional_pre-dose380.0163
GSM1296101U_lesional_pre-dose623.7371
GSM1296121V_lesional_pre-dose289.4858
GSM1296088W_lesional_pre-dose195.7753
GSM1296082X_lesional_pre-dose192.3253
GSM1296115Y_lesional_pre-dose317.1160
GSM1296084Z_lesional_pre-dose176.2850
GSM1296072B_lesional_day8360.3662
GSM1296069L_lesional_day8311.6559
GSM1296071P_lesional_day8320.9959
GSM1296070Y_lesional_day8324.1759
GSM1296073V_lesional_day8279.7758
GSM1296034A_lesional_day15431.7564
GSM1296041G_lesional_day15298.259
GSM1296035R_lesional_day15569.6770
GSM1296038U_lesional_day15426.0665
GSM1296047B_lesional_day15327.2160
GSM1296039E_lesional_day15413.7965
GSM1296042H_lesional_day15331.2660
GSM1296043L_lesional_day15288.0457
GSM1296037M_lesional_day15564.3969
GSM1296046P_lesional_day15332.3260
GSM1296044Q_lesional_day15335.5160
GSM1296045Y_lesional_day15336.8160
GSM1296025C_lesional_day15120.2545
GSM1296033D_lesional_day15215.754
GSM1296027I_lesional_day15101.5244
GSM1296032J_lesional_day15187.2351
GSM1296024K_lesional_day15143.0848
GSM1296031W_lesional_day15272.657
GSM1296028X_lesional_day15157.7549
GSM1296029Z_lesional_day15170.6450
GSM1296026F_lesional_day15158.3549
GSM1296030O_lesional_day15107.1845
GSM1296040S_lesional_day15503.4367
GSM1296036T_lesional_day15269.2956
GSM1296048V_lesional_day15344.6861
GSM1296059A_lesional_day43624.5971
GSM1296066G_lesional_day43321.1360
GSM1296060R_lesional_day43508.9568
GSM1296063U_lesional_day43391.9864
GSM1296064E_lesional_day43512.6669
GSM1296067H_lesional_day43398.5363
GSM1296062M_lesional_day43409.8164
GSM1296068Q_lesional_day43288.0957
GSM1296050C_lesional_day43164.1449
GSM1296057D_lesional_day43651.4972
GSM1296052I_lesional_day43114.1145
GSM1296054J_lesional_day43149.7547
GSM1296049K_lesional_day43182.2651
GSM1296055W_lesional_day43412.7464
GSM1296053X_lesional_day43157.1448
GSM1296058Z_lesional_day43661.3972
GSM1296051F_lesional_day43151.7349
GSM1296056O_lesional_day43624.9972
GSM1296065S_lesional_day43447.5466
GSM1296061T_lesional_day43322.4360
GSM1296095A_non-lesional_pre-dose465.5167
GSM1296120B_non-lesional_pre-dose308.4959
GSM1296077C_non-lesional_pre-dose143.8648
GSM1296093D_non-lesional_pre-dose160.5248
GSM1296104E_non-lesional_pre-dose429.0665
GSM1296079F_non-lesional_pre-dose143.9448
GSM1296108G_non-lesional_pre-dose312.8959
GSM1296110H_non-lesional_pre-dose368.5361
GSM1296081I_non-lesional_pre-dose160.9250
GSM1296091J_non-lesional_pre-dose165.3250
GSM1296075K_non-lesional_pre-dose181.4952
GSM1296112L_non-lesional_pre-dose298.2857
GSM1296100M_non-lesional_pre-dose588.6870
GSM1296087O_non-lesional_pre-dose84.0741
GSM1296118P_non-lesional_pre-dose320.4659
GSM1296114Q_non-lesional_pre-dose317.4159
GSM1296097R_non-lesional_pre-dose478.8867
GSM1296106S_non-lesional_pre-dose399.4663
GSM1296102U_non-lesional_pre-dose483.8366
GSM1296122V_non-lesional_pre-dose290.6858
GSM1296089W_non-lesional_pre-dose250.8355
GSM1296083X_non-lesional_pre-dose190.7152
GSM1296116Y_non-lesional_pre-dose299.2858
GSM1296085Z_non-lesional_pre-dose201.3253