ProfileGDS5420 / 207732_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 68% 76% 72% 56% 75% 64% 60% 47% 75% 75% 66% 59% 63% 68% 68% 60% 52% 54% 55% 65% 61% 77% 70% 57% 60% 56% 55% 63% 71% 25% 71% 65% 51% 57% 71% 59% 57% 52% 59% 54% 60% 49% 54% 51% 62% 49% 56% 54% 50% 60% 53% 47% 52% 66% 57% 63% 58% 65% 73% 40% 49% 50% 58% 54% 50% 50% 49% 52% 41% 44% 66% 69% 67% 50% 61% 59% 55% 44% 55% 53% 55% 48% 37% 69% 61% 55% 54% 53% 57% 57% 49% 54% 34% 47% 59% 38% 56% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose246.1755
GSM1296119B_lesional_pre-dose508.9668
GSM1296076C_lesional_pre-dose815.8676
GSM1296092D_lesional_pre-dose622.2872
GSM1296103E_lesional_pre-dose253.0356
GSM1296078F_lesional_pre-dose749.7375
GSM1296107G_lesional_pre-dose398.5464
GSM1296109H_lesional_pre-dose334.6260
GSM1296080I_lesional_pre-dose124.947
GSM1296090J_lesional_pre-dose759.5775
GSM1296074K_lesional_pre-dose744.1475
GSM1296111L_lesional_pre-dose441.6866
GSM1296099M_lesional_pre-dose310.659
GSM1296086O_lesional_pre-dose354.7163
GSM1296117P_lesional_pre-dose510.368
GSM1296113Q_lesional_pre-dose520.8168
GSM1296096R_lesional_pre-dose314.860
GSM1296105S_lesional_pre-dose20752
GSM1296098T_lesional_pre-dose223.8854
GSM1296101U_lesional_pre-dose234.7855
GSM1296121V_lesional_pre-dose418.5565
GSM1296088W_lesional_pre-dose329.7761
GSM1296082X_lesional_pre-dose878.2277
GSM1296115Y_lesional_pre-dose572.970
GSM1296084Z_lesional_pre-dose271.0257
GSM1296072B_lesional_day8321.7760
GSM1296069L_lesional_day8272.2956
GSM1296071P_lesional_day8266.4555
GSM1296070Y_lesional_day8398.0463
GSM1296073V_lesional_day8597.6671
GSM1296034A_lesional_day1536.6625
GSM1296041G_lesional_day15600.1871
GSM1296035R_lesional_day15432.7165
GSM1296038U_lesional_day15186.5351
GSM1296047B_lesional_day15274.9757
GSM1296039E_lesional_day15583.8271
GSM1296042H_lesional_day15308.9959
GSM1296043L_lesional_day15289.1357
GSM1296037M_lesional_day15198.1652
GSM1296046P_lesional_day15325.9559
GSM1296044Q_lesional_day15242.2254
GSM1296045Y_lesional_day15342.1860
GSM1296025C_lesional_day15161.1449
GSM1296033D_lesional_day15217.3854
GSM1296027I_lesional_day15164.2451
GSM1296032J_lesional_day15364.1162
GSM1296024K_lesional_day15150.7549
GSM1296031W_lesional_day15254.6556
GSM1296028X_lesional_day15213.6254
GSM1296029Z_lesional_day15172.4350
GSM1296026F_lesional_day15299.6660
GSM1296030O_lesional_day15191.7153
GSM1296040S_lesional_day15145.747
GSM1296036T_lesional_day15212.0152
GSM1296048V_lesional_day15463.366
GSM1296059A_lesional_day43265.1957
GSM1296066G_lesional_day43383.7263
GSM1296060R_lesional_day43292.3858
GSM1296063U_lesional_day43415.8565
GSM1296064E_lesional_day43676.9173
GSM1296067H_lesional_day43106.3540
GSM1296062M_lesional_day43164.3449
GSM1296068Q_lesional_day43201.4350
GSM1296050C_lesional_day43282.3358
GSM1296057D_lesional_day43228.954
GSM1296052I_lesional_day43163.7250
GSM1296054J_lesional_day43178.2150
GSM1296049K_lesional_day43161.8449
GSM1296055W_lesional_day43210.7152
GSM1296053X_lesional_day4394.5841
GSM1296058Z_lesional_day43109.4444
GSM1296051F_lesional_day43439.1366
GSM1296056O_lesional_day43534.1869
GSM1296065S_lesional_day43476.7267
GSM1296061T_lesional_day43182.6250
GSM1296095A_non-lesional_pre-dose338.9661
GSM1296120B_non-lesional_pre-dose301.6459
GSM1296077C_non-lesional_pre-dose222.6355
GSM1296093D_non-lesional_pre-dose127.1644
GSM1296104E_non-lesional_pre-dose232.1955
GSM1296079F_non-lesional_pre-dose200.9753
GSM1296108G_non-lesional_pre-dose247.8955
GSM1296110H_non-lesional_pre-dose171.4748
GSM1296081I_non-lesional_pre-dose67.7437
GSM1296091J_non-lesional_pre-dose534.769
GSM1296075K_non-lesional_pre-dose324.161
GSM1296112L_non-lesional_pre-dose265.3855
GSM1296100M_non-lesional_pre-dose228.9954
GSM1296087O_non-lesional_pre-dose184.953
GSM1296118P_non-lesional_pre-dose295.857
GSM1296114Q_non-lesional_pre-dose284.4557
GSM1296097R_non-lesional_pre-dose166.1349
GSM1296106S_non-lesional_pre-dose236.3154
GSM1296102U_non-lesional_pre-dose65.4134
GSM1296122V_non-lesional_pre-dose158.3747
GSM1296089W_non-lesional_pre-dose304.9359
GSM1296083X_non-lesional_pre-dose76.4238
GSM1296116Y_non-lesional_pre-dose275.9356
GSM1296085Z_non-lesional_pre-dose294.5959