ProfileGDS5420 / 207356_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 66% 73% 73% 99% 99% 44% 99% 99% 99% 52% 99% 99% 54% 43% 54% 50% 85% 38% 95% 38% 28% 70% 37% 34% 46% 99% 99% 99% 99% 99% 99% 99% 99% 99% 99% 44% 99% 33% 33% 73% 38% 30% 66% 60% 36% 67% 99% 99% 99% 99% 83% 38% 47% 33% 98% 37% 21% 37% 64% 66% 83% 31% 31% 83% 27% 34% 65% 65% 30% 30% 18% 98% 31% 17% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose13495.199
GSM1296119B_lesional_pre-dose10473.199
GSM1296076C_lesional_pre-dose13690.199
GSM1296092D_lesional_pre-dose12183.899
GSM1296103E_lesional_pre-dose15395.599
GSM1296078F_lesional_pre-dose12545.299
GSM1296107G_lesional_pre-dose10265.599
GSM1296109H_lesional_pre-dose12007.299
GSM1296080I_lesional_pre-dose8537.8499
GSM1296090J_lesional_pre-dose1383799
GSM1296074K_lesional_pre-dose14534.599
GSM1296111L_lesional_pre-dose10310.199
GSM1296099M_lesional_pre-dose8165.899
GSM1296086O_lesional_pre-dose12783.699
GSM1296117P_lesional_pre-dose9784.199
GSM1296113Q_lesional_pre-dose8968.0399
GSM1296096R_lesional_pre-dose12065.199
GSM1296105S_lesional_pre-dose9523.4299
GSM1296098T_lesional_pre-dose16661.199
GSM1296101U_lesional_pre-dose18971.299
GSM1296121V_lesional_pre-dose11889.999
GSM1296088W_lesional_pre-dose10556.899
GSM1296082X_lesional_pre-dose14566.799
GSM1296115Y_lesional_pre-dose11496.899
GSM1296084Z_lesional_pre-dose9945.0599
GSM1296072B_lesional_day8458.1866
GSM1296069L_lesional_day8684.873
GSM1296071P_lesional_day8703.1473
GSM1296070Y_lesional_day85800.2999
GSM1296073V_lesional_day811549.899
GSM1296034A_lesional_day15126.844
GSM1296041G_lesional_day1510565.499
GSM1296035R_lesional_day1512387.499
GSM1296038U_lesional_day157742.0499
GSM1296047B_lesional_day15205.0852
GSM1296039E_lesional_day1523277.599
GSM1296042H_lesional_day156860.9799
GSM1296043L_lesional_day15249.354
GSM1296037M_lesional_day15116.5743
GSM1296046P_lesional_day15243.5854
GSM1296044Q_lesional_day1520050
GSM1296045Y_lesional_day151440.8685
GSM1296025C_lesional_day1580.2838
GSM1296033D_lesional_day153146.1595
GSM1296027I_lesional_day1568.5438
GSM1296032J_lesional_day1541.5928
GSM1296024K_lesional_day15558.6970
GSM1296031W_lesional_day1581.637
GSM1296028X_lesional_day1559.8634
GSM1296029Z_lesional_day15133.8746
GSM1296026F_lesional_day158176.0799
GSM1296030O_lesional_day1510739.999
GSM1296040S_lesional_day151214499
GSM1296036T_lesional_day1511221.399
GSM1296048V_lesional_day1511371.999
GSM1296059A_lesional_day4313726.199
GSM1296066G_lesional_day436447.8299
GSM1296060R_lesional_day4310705.699
GSM1296063U_lesional_day4311499.999
GSM1296064E_lesional_day4317425.699
GSM1296067H_lesional_day43140.3244
GSM1296062M_lesional_day436249.7799
GSM1296068Q_lesional_day4377.1833
GSM1296050C_lesional_day4358.733
GSM1296057D_lesional_day43696.7173
GSM1296052I_lesional_day4371.3438
GSM1296054J_lesional_day4348.3930
GSM1296049K_lesional_day43465.266
GSM1296055W_lesional_day43336.2160
GSM1296053X_lesional_day4368.9636
GSM1296058Z_lesional_day43498.0267
GSM1296051F_lesional_day4311353.299
GSM1296056O_lesional_day4317158.599
GSM1296065S_lesional_day437836.3699
GSM1296061T_lesional_day4310953.699
GSM1296095A_non-lesional_pre-dose1340.4183
GSM1296120B_non-lesional_pre-dose94.0938
GSM1296077C_non-lesional_pre-dose135.9447
GSM1296093D_non-lesional_pre-dose61.233
GSM1296104E_non-lesional_pre-dose7087.0698
GSM1296079F_non-lesional_pre-dose71.8737
GSM1296108G_non-lesional_pre-dose27.7321
GSM1296110H_non-lesional_pre-dose91.4337
GSM1296081I_non-lesional_pre-dose389.1264
GSM1296091J_non-lesional_pre-dose441.9866
GSM1296075K_non-lesional_pre-dose1297.3883
GSM1296112L_non-lesional_pre-dose69.6731
GSM1296100M_non-lesional_pre-dose52.2931
GSM1296087O_non-lesional_pre-dose1388.5483
GSM1296118P_non-lesional_pre-dose49.0527
GSM1296114Q_non-lesional_pre-dose75.6434
GSM1296097R_non-lesional_pre-dose418.465
GSM1296106S_non-lesional_pre-dose440.2165
GSM1296102U_non-lesional_pre-dose48.9830
GSM1296122V_non-lesional_pre-dose55.5730
GSM1296089W_non-lesional_pre-dose22.5218
GSM1296083X_non-lesional_pre-dose5617.4998
GSM1296116Y_non-lesional_pre-dose67.8431
GSM1296085Z_non-lesional_pre-dose19.2417