ProfileGDS5420 / 206636_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 53% 60% 52% 44% 53% 48% 63% 60% 45% 46% 45% 65% 49% 46% 59% 64% 51% 53% 55% 53% 59% 50% 50% 66% 48% 55% 65% 58% 62% 55% 52% 65% 47% 51% 54% 47% 64% 59% 43% 64% 63% 61% 54% 34% 36% 47% 50% 49% 43% 43% 41% 42% 53% 61% 56% 48% 63% 47% 47% 55% 58% 50% 59% 51% 42% 48% 51% 55% 43% 46% 39% 47% 42% 48% 57% 50% 54% 48% 58% 48% 48% 59% 61% 38% 44% 45% 64% 45% 42% 62% 66% 42% 48% 51% 49% 47% 41% 64% 42% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose212.253
GSM1296119B_lesional_pre-dose315.1260
GSM1296076C_lesional_pre-dose179.1352
GSM1296092D_lesional_pre-dose99.3244
GSM1296103E_lesional_pre-dose199.7353
GSM1296078F_lesional_pre-dose136.6948
GSM1296107G_lesional_pre-dose372.1263
GSM1296109H_lesional_pre-dose338.2660
GSM1296080I_lesional_pre-dose115.6545
GSM1296090J_lesional_pre-dose127.2446
GSM1296074K_lesional_pre-dose108.4445
GSM1296111L_lesional_pre-dose421.0465
GSM1296099M_lesional_pre-dose168.6549
GSM1296086O_lesional_pre-dose121.3546
GSM1296117P_lesional_pre-dose316.0759
GSM1296113Q_lesional_pre-dose410.4364
GSM1296096R_lesional_pre-dose180.2851
GSM1296105S_lesional_pre-dose215.2253
GSM1296098T_lesional_pre-dose234.8755
GSM1296101U_lesional_pre-dose215.5253
GSM1296121V_lesional_pre-dose305.9659
GSM1296088W_lesional_pre-dose164.2850
GSM1296082X_lesional_pre-dose159.5550
GSM1296115Y_lesional_pre-dose443.8166
GSM1296084Z_lesional_pre-dose153.448
GSM1296072B_lesional_day8243.4755
GSM1296069L_lesional_day8451.4765
GSM1296071P_lesional_day8300.6258
GSM1296070Y_lesional_day8378.8362
GSM1296073V_lesional_day8232.6455
GSM1296034A_lesional_day15215.3552
GSM1296041G_lesional_day15434.365
GSM1296035R_lesional_day15138.3247
GSM1296038U_lesional_day15184.9551
GSM1296047B_lesional_day15229.1654
GSM1296039E_lesional_day15143.3447
GSM1296042H_lesional_day1541364
GSM1296043L_lesional_day15312.6759
GSM1296037M_lesional_day15117.7143
GSM1296046P_lesional_day15406.4564
GSM1296044Q_lesional_day15400.3363
GSM1296045Y_lesional_day15358.0861
GSM1296025C_lesional_day1521554
GSM1296033D_lesional_day1558.6934
GSM1296027I_lesional_day1558.5336
GSM1296032J_lesional_day15140.7247
GSM1296024K_lesional_day15168.350
GSM1296031W_lesional_day15172.2749
GSM1296028X_lesional_day15104.8643
GSM1296029Z_lesional_day15110.3343
GSM1296026F_lesional_day1596.9541
GSM1296030O_lesional_day1585.442
GSM1296040S_lesional_day15214.9353
GSM1296036T_lesional_day15351.1561
GSM1296048V_lesional_day15258.0456
GSM1296059A_lesional_day43144.6148
GSM1296066G_lesional_day43385.8363
GSM1296060R_lesional_day43145.1447
GSM1296063U_lesional_day43144.2147
GSM1296064E_lesional_day43223.7355
GSM1296067H_lesional_day43312.2358
GSM1296062M_lesional_day43172.5150
GSM1296068Q_lesional_day43328.5659
GSM1296050C_lesional_day43177.5951
GSM1296057D_lesional_day43100.3742
GSM1296052I_lesional_day43139.9248
GSM1296054J_lesional_day43188.4151
GSM1296049K_lesional_day43227.8955
GSM1296055W_lesional_day43116.8543
GSM1296053X_lesional_day43137.7946
GSM1296058Z_lesional_day4378.3439
GSM1296051F_lesional_day43138.647
GSM1296056O_lesional_day4395.0542
GSM1296065S_lesional_day43158.948
GSM1296061T_lesional_day43281.1357
GSM1296095A_non-lesional_pre-dose162.9150
GSM1296120B_non-lesional_pre-dose234.7854
GSM1296077C_non-lesional_pre-dose142.9548
GSM1296093D_non-lesional_pre-dose298.1958
GSM1296104E_non-lesional_pre-dose158.1148
GSM1296079F_non-lesional_pre-dose146.2648
GSM1296108G_non-lesional_pre-dose313.5259
GSM1296110H_non-lesional_pre-dose365.6461
GSM1296081I_non-lesional_pre-dose70.7238
GSM1296091J_non-lesional_pre-dose109.1644
GSM1296075K_non-lesional_pre-dose115.0645
GSM1296112L_non-lesional_pre-dose433.5864
GSM1296100M_non-lesional_pre-dose131.8445
GSM1296087O_non-lesional_pre-dose89.5342
GSM1296118P_non-lesional_pre-dose376.0262
GSM1296114Q_non-lesional_pre-dose466.9666
GSM1296097R_non-lesional_pre-dose103.9342
GSM1296106S_non-lesional_pre-dose166.5448
GSM1296102U_non-lesional_pre-dose200.7251
GSM1296122V_non-lesional_pre-dose175.0649
GSM1296089W_non-lesional_pre-dose156.6247
GSM1296083X_non-lesional_pre-dose98.9941
GSM1296116Y_non-lesional_pre-dose431.0364
GSM1296085Z_non-lesional_pre-dose105.1542