ProfileGDS5420 / 206109_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 86% 85% 93% 91% 87% 92% 85% 90% 79% 90% 93% 91% 89% 85% 88% 86% 91% 76% 79% 83% 86% 80% 92% 93% 79% 79% 79% 76% 89% 89% 68% 91% 90% 85% 73% 90% 88% 83% 69% 76% 76% 87% 68% 78% 54% 69% 62% 64% 67% 74% 80% 75% 83% 77% 88% 89% 86% 89% 90% 91% 75% 80% 77% 74% 82% 65% 61% 63% 75% 60% 88% 85% 91% 82% 80% 84% 73% 73% 57% 77% 66% 72% 69% 50% 77% 77% 73% 69% 70% 66% 75% 81% 74% 69% 67% 69% 62% 82% 63% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1552.7786
GSM1296119B_lesional_pre-dose1429.8185
GSM1296076C_lesional_pre-dose3154.2593
GSM1296092D_lesional_pre-dose2471.9591
GSM1296103E_lesional_pre-dose1705.8787
GSM1296078F_lesional_pre-dose2770.2892
GSM1296107G_lesional_pre-dose1464.4285
GSM1296109H_lesional_pre-dose2141.6990
GSM1296080I_lesional_pre-dose1017.7679
GSM1296090J_lesional_pre-dose2161.8690
GSM1296074K_lesional_pre-dose3355.1293
GSM1296111L_lesional_pre-dose2290.8891
GSM1296099M_lesional_pre-dose1897.3989
GSM1296086O_lesional_pre-dose1559.7785
GSM1296117P_lesional_pre-dose1829.5988
GSM1296113Q_lesional_pre-dose1549.7186
GSM1296096R_lesional_pre-dose2357.1291
GSM1296105S_lesional_pre-dose812.0576
GSM1296098T_lesional_pre-dose996.0279
GSM1296101U_lesional_pre-dose1295.0983
GSM1296121V_lesional_pre-dose1527.0486
GSM1296088W_lesional_pre-dose1067.3680
GSM1296082X_lesional_pre-dose2822.992
GSM1296115Y_lesional_pre-dose2771.5793
GSM1296084Z_lesional_pre-dose986.8579
GSM1296072B_lesional_day8964.3379
GSM1296069L_lesional_day8961.3879
GSM1296071P_lesional_day8798.4776
GSM1296070Y_lesional_day81810.8989
GSM1296073V_lesional_day82106.0189
GSM1296034A_lesional_day15531.2568
GSM1296041G_lesional_day152445.4691
GSM1296035R_lesional_day152214.3290
GSM1296038U_lesional_day151527.2685
GSM1296047B_lesional_day15693.3373
GSM1296039E_lesional_day152343.5190
GSM1296042H_lesional_day151750.8988
GSM1296043L_lesional_day151273.5183
GSM1296037M_lesional_day15555.9869
GSM1296046P_lesional_day15820.5176
GSM1296044Q_lesional_day15812.3376
GSM1296045Y_lesional_day151573.6287
GSM1296025C_lesional_day15494.6668
GSM1296033D_lesional_day15926.5978
GSM1296027I_lesional_day15196.654
GSM1296032J_lesional_day15541.1369
GSM1296024K_lesional_day15345.0762
GSM1296031W_lesional_day15425.8664
GSM1296028X_lesional_day15490.2767
GSM1296029Z_lesional_day15755.2174
GSM1296026F_lesional_day151055.4780
GSM1296030O_lesional_day15774.5775
GSM1296040S_lesional_day151246.7583
GSM1296036T_lesional_day15897.5777
GSM1296048V_lesional_day151900.5488
GSM1296059A_lesional_day431995.0889
GSM1296066G_lesional_day431560.1386
GSM1296060R_lesional_day432041.7989
GSM1296063U_lesional_day432158.2290
GSM1296064E_lesional_day432476.0891
GSM1296067H_lesional_day43803.1875
GSM1296062M_lesional_day431067.8680
GSM1296068Q_lesional_day43848.5877
GSM1296050C_lesional_day43717.0174
GSM1296057D_lesional_day431228.2482
GSM1296052I_lesional_day43406.4965
GSM1296054J_lesional_day43350.9961
GSM1296049K_lesional_day43384.0663
GSM1296055W_lesional_day43780.9475
GSM1296053X_lesional_day43323.5460
GSM1296058Z_lesional_day431852.9388
GSM1296051F_lesional_day431478.2385
GSM1296056O_lesional_day432617.1891
GSM1296065S_lesional_day431206.5882
GSM1296061T_lesional_day43105080
GSM1296095A_non-lesional_pre-dose1430.5184
GSM1296120B_non-lesional_pre-dose685.1573
GSM1296077C_non-lesional_pre-dose668.3473
GSM1296093D_non-lesional_pre-dose287.2757
GSM1296104E_non-lesional_pre-dose873.8677
GSM1296079F_non-lesional_pre-dose440.6566
GSM1296108G_non-lesional_pre-dose652.5472
GSM1296110H_non-lesional_pre-dose544.2869
GSM1296081I_non-lesional_pre-dose155.6750
GSM1296091J_non-lesional_pre-dose882.2777
GSM1296075K_non-lesional_pre-dose871.8777
GSM1296112L_non-lesional_pre-dose707.5473
GSM1296100M_non-lesional_pre-dose560.7969
GSM1296087O_non-lesional_pre-dose564.5870
GSM1296118P_non-lesional_pre-dose471.9466
GSM1296114Q_non-lesional_pre-dose787.6575
GSM1296097R_non-lesional_pre-dose1150.581
GSM1296106S_non-lesional_pre-dose720.0874
GSM1296102U_non-lesional_pre-dose558.2769
GSM1296122V_non-lesional_pre-dose480.5367
GSM1296089W_non-lesional_pre-dose549.6869
GSM1296083X_non-lesional_pre-dose370.6362
GSM1296116Y_non-lesional_pre-dose1125.6482
GSM1296085Z_non-lesional_pre-dose379.163