ProfileGDS5420 / 205913_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 32% 67% 58% 66% 31% 89% 98% 58% 41% 73% 59% 88% 49% 81% 55% 82% 42% 95% 52% 59% 82% 64% 18% 88% 30% 76% 91% 86% 93% 78% 58% 95% 25% 92% 71% 29% 87% 91% 67% 85% 96% 98% 88% 80% 81% 97% 81% 98% 59% 61% 76% 64% 82% 50% 85% 46% 97% 57% 98% 81% 81% 56% 99% 99% 92% 77% 57% 85% 97% 56% 69% 85% 71% 99% 82% 82% 60% 91% 91% 57% 86% 99% 81% 99% 70% 95% 99% 73% 94% 90% 85% 75% 96% 78% 95% 88% 99% 96% 87% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose52.0132
GSM1296119B_lesional_pre-dose468.4267
GSM1296076C_lesional_pre-dose260.3558
GSM1296092D_lesional_pre-dose428.0566
GSM1296103E_lesional_pre-dose49.4231
GSM1296078F_lesional_pre-dose2120.8589
GSM1296107G_lesional_pre-dose6579.2798
GSM1296109H_lesional_pre-dose291.3858
GSM1296080I_lesional_pre-dose90.4541
GSM1296090J_lesional_pre-dose666.7573
GSM1296074K_lesional_pre-dose270.8859
GSM1296111L_lesional_pre-dose1793.888
GSM1296099M_lesional_pre-dose162.7349
GSM1296086O_lesional_pre-dose1140.9881
GSM1296117P_lesional_pre-dose250.2155
GSM1296113Q_lesional_pre-dose1127.8482
GSM1296096R_lesional_pre-dose98.1242
GSM1296105S_lesional_pre-dose3377.9495
GSM1296098T_lesional_pre-dose204.8452
GSM1296101U_lesional_pre-dose302.9759
GSM1296121V_lesional_pre-dose1205.3882
GSM1296088W_lesional_pre-dose388.8264
GSM1296082X_lesional_pre-dose18.2118
GSM1296115Y_lesional_pre-dose1875.188
GSM1296084Z_lesional_pre-dose50.1130
GSM1296072B_lesional_day8815.276
GSM1296069L_lesional_day82257.391
GSM1296071P_lesional_day81500.7786
GSM1296070Y_lesional_day82486.7893
GSM1296073V_lesional_day8930.5678
GSM1296034A_lesional_day15301.0958
GSM1296041G_lesional_day153673.5195
GSM1296035R_lesional_day1528.3225
GSM1296038U_lesional_day152623.6692
GSM1296047B_lesional_day15624.0671
GSM1296039E_lesional_day1544.529
GSM1296042H_lesional_day151595.3687
GSM1296043L_lesional_day152208.7391
GSM1296037M_lesional_day15486.0967
GSM1296046P_lesional_day151446.3585
GSM1296044Q_lesional_day153523.2996
GSM1296045Y_lesional_day154614.4698
GSM1296025C_lesional_day151914.388
GSM1296033D_lesional_day151099.2580
GSM1296027I_lesional_day151173.7881
GSM1296032J_lesional_day154444.797
GSM1296024K_lesional_day151185.4781
GSM1296031W_lesional_day155298.2598
GSM1296028X_lesional_day15299.1359
GSM1296029Z_lesional_day15334.8661
GSM1296026F_lesional_day15821.9976
GSM1296030O_lesional_day15382.264
GSM1296040S_lesional_day151230.5482
GSM1296036T_lesional_day15188.0950
GSM1296048V_lesional_day151475.3185
GSM1296059A_lesional_day43128.4546
GSM1296066G_lesional_day434650.0697
GSM1296060R_lesional_day43266.2457
GSM1296063U_lesional_day435911.0698
GSM1296064E_lesional_day431171.4581
GSM1296067H_lesional_day431077.7881
GSM1296062M_lesional_day43256.3856
GSM1296068Q_lesional_day436907.7999
GSM1296050C_lesional_day437078.5799
GSM1296057D_lesional_day432439.1492
GSM1296052I_lesional_day43892.8477
GSM1296054J_lesional_day43273.1857
GSM1296049K_lesional_day431510.2685
GSM1296055W_lesional_day434255.6597
GSM1296053X_lesional_day43253.656
GSM1296058Z_lesional_day43538.9469
GSM1296051F_lesional_day431573.2485
GSM1296056O_lesional_day43590.4571
GSM1296065S_lesional_day436199.2699
GSM1296061T_lesional_day431226.8982
GSM1296095A_non-lesional_pre-dose1226.8882
GSM1296120B_non-lesional_pre-dose333.4960
GSM1296077C_non-lesional_pre-dose2328.5291
GSM1296093D_non-lesional_pre-dose2259.5791
GSM1296104E_non-lesional_pre-dose268.0457
GSM1296079F_non-lesional_pre-dose166786
GSM1296108G_non-lesional_pre-dose8470.7199
GSM1296110H_non-lesional_pre-dose1072.8181
GSM1296081I_non-lesional_pre-dose10128.699
GSM1296091J_non-lesional_pre-dose580.8870
GSM1296075K_non-lesional_pre-dose3607.5795
GSM1296112L_non-lesional_pre-dose5473.2799
GSM1296100M_non-lesional_pre-dose698.0773
GSM1296087O_non-lesional_pre-dose3266.3194
GSM1296118P_non-lesional_pre-dose1910.6290
GSM1296114Q_non-lesional_pre-dose1460.8985
GSM1296097R_non-lesional_pre-dose752.4275
GSM1296106S_non-lesional_pre-dose3623.3596
GSM1296102U_non-lesional_pre-dose925.0878
GSM1296122V_non-lesional_pre-dose3350.595
GSM1296089W_non-lesional_pre-dose1710.3388
GSM1296083X_non-lesional_pre-dose8752.5899
GSM1296116Y_non-lesional_pre-dose3400.0996
GSM1296085Z_non-lesional_pre-dose1643.9687