ProfileGDS5420 / 205715_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 38% 63% 55% 47% 42% 54% 55% 35% 38% 55% 49% 55% 54% 45% 48% 51% 50% 50% 35% 45% 49% 50% 49% 55% 46% 61% 63% 57% 60% 58% 32% 56% 48% 57% 57% 46% 56% 60% 53% 55% 59% 65% 48% 38% 45% 46% 41% 58% 49% 48% 53% 47% 47% 30% 59% 43% 56% 53% 60% 52% 58% 42% 63% 63% 57% 49% 40% 44% 67% 49% 56% 55% 56% 60% 39% 56% 60% 57% 35% 50% 54% 63% 57% 42% 50% 53% 59% 44% 55% 52% 56% 58% 56% 50% 59% 60% 51% 54% 45% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose76.6438
GSM1296119B_lesional_pre-dose373.3563
GSM1296076C_lesional_pre-dose214.2455
GSM1296092D_lesional_pre-dose124.2847
GSM1296103E_lesional_pre-dose98.8642
GSM1296078F_lesional_pre-dose196.0654
GSM1296107G_lesional_pre-dose237.5455
GSM1296109H_lesional_pre-dose75.435
GSM1296080I_lesional_pre-dose70.8838
GSM1296090J_lesional_pre-dose213.7555
GSM1296074K_lesional_pre-dose141.1549
GSM1296111L_lesional_pre-dose249.955
GSM1296099M_lesional_pre-dose222.454
GSM1296086O_lesional_pre-dose115.4145
GSM1296117P_lesional_pre-dose167.7448
GSM1296113Q_lesional_pre-dose209.6251
GSM1296096R_lesional_pre-dose170.0350
GSM1296105S_lesional_pre-dose182.6550
GSM1296098T_lesional_pre-dose73.9835
GSM1296101U_lesional_pre-dose132.4445
GSM1296121V_lesional_pre-dose167.649
GSM1296088W_lesional_pre-dose161.5250
GSM1296082X_lesional_pre-dose149.4649
GSM1296115Y_lesional_pre-dose239.6755
GSM1296084Z_lesional_pre-dose134.1946
GSM1296072B_lesional_day8336.761
GSM1296069L_lesional_day8393.1963
GSM1296071P_lesional_day8289.2957
GSM1296070Y_lesional_day8334.2760
GSM1296073V_lesional_day8275.4958
GSM1296034A_lesional_day1559.8632
GSM1296041G_lesional_day15248.4356
GSM1296035R_lesional_day15145.7848
GSM1296038U_lesional_day15262.1657
GSM1296047B_lesional_day15273.2857
GSM1296039E_lesional_day15131.9146
GSM1296042H_lesional_day15260.7956
GSM1296043L_lesional_day15342.4460
GSM1296037M_lesional_day15222.7353
GSM1296046P_lesional_day15260.3655
GSM1296044Q_lesional_day15325.3759
GSM1296045Y_lesional_day15433.2565
GSM1296025C_lesional_day15147.1648
GSM1296033D_lesional_day1577.6438
GSM1296027I_lesional_day15109.5745
GSM1296032J_lesional_day15133.7346
GSM1296024K_lesional_day1593.7441
GSM1296031W_lesional_day15288.958
GSM1296028X_lesional_day15159.3449
GSM1296029Z_lesional_day15153.948
GSM1296026F_lesional_day15198.2853
GSM1296030O_lesional_day15124.9547
GSM1296040S_lesional_day15149.0847
GSM1296036T_lesional_day1553.3130
GSM1296048V_lesional_day15304.1559
GSM1296059A_lesional_day43106.3943
GSM1296066G_lesional_day43266.456
GSM1296060R_lesional_day43215.1953
GSM1296063U_lesional_day43321.1560
GSM1296064E_lesional_day43184.6552
GSM1296067H_lesional_day43306.7858
GSM1296062M_lesional_day43102.8942
GSM1296068Q_lesional_day43412.7763
GSM1296050C_lesional_day43377.1363
GSM1296057D_lesional_day43264.8357
GSM1296052I_lesional_day43152.5649
GSM1296054J_lesional_day4394.6740
GSM1296049K_lesional_day43119.1844
GSM1296055W_lesional_day43485.2767
GSM1296053X_lesional_day43161.0849
GSM1296058Z_lesional_day43252.3256
GSM1296051F_lesional_day43224.9655
GSM1296056O_lesional_day43230.1756
GSM1296065S_lesional_day43319.0760
GSM1296061T_lesional_day4388.5639
GSM1296095A_non-lesional_pre-dose240.8956
GSM1296120B_non-lesional_pre-dose319.7860
GSM1296077C_non-lesional_pre-dose261.757
GSM1296093D_non-lesional_pre-dose69.3735
GSM1296104E_non-lesional_pre-dose178.1150
GSM1296079F_non-lesional_pre-dose208.8254
GSM1296108G_non-lesional_pre-dose396.0863
GSM1296110H_non-lesional_pre-dose298.0157
GSM1296081I_non-lesional_pre-dose96.0642
GSM1296091J_non-lesional_pre-dose166.7350
GSM1296075K_non-lesional_pre-dose188.0453
GSM1296112L_non-lesional_pre-dose318.8559
GSM1296100M_non-lesional_pre-dose123.7944
GSM1296087O_non-lesional_pre-dose209.4355
GSM1296118P_non-lesional_pre-dose221.252
GSM1296114Q_non-lesional_pre-dose271.5256
GSM1296097R_non-lesional_pre-dose289.0458
GSM1296106S_non-lesional_pre-dose263.8656
GSM1296102U_non-lesional_pre-dose192.4750
GSM1296122V_non-lesional_pre-dose311.2559
GSM1296089W_non-lesional_pre-dose332.1760
GSM1296083X_non-lesional_pre-dose181.6751
GSM1296116Y_non-lesional_pre-dose248.8454
GSM1296085Z_non-lesional_pre-dose124.7145