ProfileGDS5420 / 205280_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 16% 44% 29% 31% 15% 33% 35% 15% 12% 39% 24% 37% 24% 20% 23% 34% 29% 34% 4% 22% 28% 23% 24% 34% 19% 41% 37% 46% 43% 38% 20% 35% 27% 36% 39% 11% 42% 41% 50% 46% 47% 48% 28% 36% 39% 41% 39% 35% 40% 32% 35% 30% 16% 22% 46% 17% 36% 17% 49% 37% 30% 30% 55% 45% 42% 39% 31% 31% 50% 17% 49% 41% 26% 47% 4% 38% 47% 45% 21% 43% 43% 38% 37% 44% 39% 48% 47% 37% 20% 44% 41% 37% 40% 35% 47% 46% 38% 38% 38% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose17.4716
GSM1296119B_lesional_pre-dose125.2944
GSM1296076C_lesional_pre-dose44.1429
GSM1296092D_lesional_pre-dose42.8631
GSM1296103E_lesional_pre-dose14.7215
GSM1296078F_lesional_pre-dose56.1433
GSM1296107G_lesional_pre-dose72.9235
GSM1296109H_lesional_pre-dose19.0515
GSM1296080I_lesional_pre-dose11.8412
GSM1296090J_lesional_pre-dose80.9739
GSM1296074K_lesional_pre-dose28.3524
GSM1296111L_lesional_pre-dose87.0737
GSM1296099M_lesional_pre-dose31.3924
GSM1296086O_lesional_pre-dose21.7620
GSM1296117P_lesional_pre-dose36.3623
GSM1296113Q_lesional_pre-dose79.8634
GSM1296096R_lesional_pre-dose40.5329
GSM1296105S_lesional_pre-dose67.0734
GSM1296098T_lesional_pre-dose6.154
GSM1296101U_lesional_pre-dose27.8522
GSM1296121V_lesional_pre-dose44.2228
GSM1296088W_lesional_pre-dose27.8823
GSM1296082X_lesional_pre-dose28.0824
GSM1296115Y_lesional_pre-dose70.4634
GSM1296084Z_lesional_pre-dose24.5319
GSM1296072B_lesional_day8109.9241
GSM1296069L_lesional_day892.4837
GSM1296071P_lesional_day8158.6846
GSM1296070Y_lesional_day8129.8143
GSM1296073V_lesional_day88538
GSM1296034A_lesional_day1526.1720
GSM1296041G_lesional_day1573.4435
GSM1296035R_lesional_day1533.927
GSM1296038U_lesional_day1570.9836
GSM1296047B_lesional_day1599.9839
GSM1296039E_lesional_day1512.7111
GSM1296042H_lesional_day15116.5342
GSM1296043L_lesional_day15116.2341
GSM1296037M_lesional_day15182.4250
GSM1296046P_lesional_day15155.6346
GSM1296044Q_lesional_day15163.7947
GSM1296045Y_lesional_day15173.1148
GSM1296025C_lesional_day1541.1828
GSM1296033D_lesional_day1566.2336
GSM1296027I_lesional_day1570.4439
GSM1296032J_lesional_day1594.6941
GSM1296024K_lesional_day1577.9839
GSM1296031W_lesional_day1570.9535
GSM1296028X_lesional_day1588.5840
GSM1296029Z_lesional_day1550.5332
GSM1296026F_lesional_day1564.9735
GSM1296030O_lesional_day1538.5230
GSM1296040S_lesional_day1518.3316
GSM1296036T_lesional_day1529.1322
GSM1296048V_lesional_day15138.5946
GSM1296059A_lesional_day4316.9817
GSM1296066G_lesional_day4381.1736
GSM1296060R_lesional_day4317.7917
GSM1296063U_lesional_day43165.7549
GSM1296064E_lesional_day4370.8837
GSM1296067H_lesional_day4355.3730
GSM1296062M_lesional_day4344.8730
GSM1296068Q_lesional_day43260.1955
GSM1296050C_lesional_day43130.2545
GSM1296057D_lesional_day43104.7542
GSM1296052I_lesional_day4375.2539
GSM1296054J_lesional_day4351.8731
GSM1296049K_lesional_day4351.2331
GSM1296055W_lesional_day43185.9950
GSM1296053X_lesional_day4318.1517
GSM1296058Z_lesional_day43152.5349
GSM1296051F_lesional_day4391.5941
GSM1296056O_lesional_day4332.4226
GSM1296065S_lesional_day43145.8247
GSM1296061T_lesional_day435.24
GSM1296095A_non-lesional_pre-dose76.7738
GSM1296120B_non-lesional_pre-dose157.8447
GSM1296077C_non-lesional_pre-dose116.2645
GSM1296093D_non-lesional_pre-dose27.5121
GSM1296104E_non-lesional_pre-dose110.9743
GSM1296079F_non-lesional_pre-dose105.543
GSM1296108G_non-lesional_pre-dose91.2438
GSM1296110H_non-lesional_pre-dose95.1837
GSM1296081I_non-lesional_pre-dose111.2444
GSM1296091J_non-lesional_pre-dose80.4139
GSM1296075K_non-lesional_pre-dose138.3748
GSM1296112L_non-lesional_pre-dose171.0247
GSM1296100M_non-lesional_pre-dose80.4337
GSM1296087O_non-lesional_pre-dose21.7620
GSM1296118P_non-lesional_pre-dose140.7144
GSM1296114Q_non-lesional_pre-dose117.141
GSM1296097R_non-lesional_pre-dose73.9637
GSM1296106S_non-lesional_pre-dose102.8740
GSM1296102U_non-lesional_pre-dose70.535
GSM1296122V_non-lesional_pre-dose157.9447
GSM1296089W_non-lesional_pre-dose143.8146
GSM1296083X_non-lesional_pre-dose77.9838
GSM1296116Y_non-lesional_pre-dose99.4938
GSM1296085Z_non-lesional_pre-dose79.6538