ProfileGDS5420 / 204361_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 40% 60% 53% 54% 40% 50% 60% 45% 42% 52% 50% 60% 43% 45% 55% 59% 43% 40% 40% 38% 54% 52% 53% 55% 45% 57% 59% 56% 52% 53% 38% 55% 42% 43% 55% 53% 57% 53% 37% 54% 59% 55% 29% 45% 46% 54% 36% 45% 46% 37% 32% 32% 29% 37% 52% 39% 54% 42% 45% 48% 46% 41% 59% 54% 50% 48% 41% 42% 44% 38% 29% 50% 42% 50% 31% 53% 59% 40% 35% 53% 40% 57% 54% 27% 56% 56% 53% 35% 36% 57% 62% 45% 49% 35% 50% 44% 43% 56% 39% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose89.3640
GSM1296119B_lesional_pre-dose312.960
GSM1296076C_lesional_pre-dose185.6353
GSM1296092D_lesional_pre-dose195.1554
GSM1296103E_lesional_pre-dose90.3840
GSM1296078F_lesional_pre-dose156.2250
GSM1296107G_lesional_pre-dose318.2360
GSM1296109H_lesional_pre-dose14245
GSM1296080I_lesional_pre-dose92.7542
GSM1296090J_lesional_pre-dose185.3552
GSM1296074K_lesional_pre-dose14850
GSM1296111L_lesional_pre-dose314.4660
GSM1296099M_lesional_pre-dose115.1943
GSM1296086O_lesional_pre-dose115.4745
GSM1296117P_lesional_pre-dose250.9955
GSM1296113Q_lesional_pre-dose314.8859
GSM1296096R_lesional_pre-dose106.1143
GSM1296105S_lesional_pre-dose95.8940
GSM1296098T_lesional_pre-dose95.3840
GSM1296101U_lesional_pre-dose82.7838
GSM1296121V_lesional_pre-dose230.4354
GSM1296088W_lesional_pre-dose188.5452
GSM1296082X_lesional_pre-dose184.6653
GSM1296115Y_lesional_pre-dose247.655
GSM1296084Z_lesional_pre-dose122.7945
GSM1296072B_lesional_day8273.8857
GSM1296069L_lesional_day8318.9659
GSM1296071P_lesional_day8270.9956
GSM1296070Y_lesional_day8212.5952
GSM1296073V_lesional_day8205.6253
GSM1296034A_lesional_day1588.8738
GSM1296041G_lesional_day15233.0755
GSM1296035R_lesional_day15101.1742
GSM1296038U_lesional_day15106.7143
GSM1296047B_lesional_day15251.755
GSM1296039E_lesional_day15207.6153
GSM1296042H_lesional_day15272.157
GSM1296043L_lesional_day15231.3353
GSM1296037M_lesional_day1582.1437
GSM1296046P_lesional_day15240.4454
GSM1296044Q_lesional_day15315.3859
GSM1296045Y_lesional_day15249.6355
GSM1296025C_lesional_day1544.7929
GSM1296033D_lesional_day15119.5245
GSM1296027I_lesional_day15114.9646
GSM1296032J_lesional_day15220.8854
GSM1296024K_lesional_day1566.1736
GSM1296031W_lesional_day15133.1445
GSM1296028X_lesional_day15134.5846
GSM1296029Z_lesional_day1571.1937
GSM1296026F_lesional_day1554.5332
GSM1296030O_lesional_day1543.8332
GSM1296040S_lesional_day1547.5329
GSM1296036T_lesional_day1580.2737
GSM1296048V_lesional_day15204.952
GSM1296059A_lesional_day4381.4639
GSM1296066G_lesional_day43236.8854
GSM1296060R_lesional_day4399.3642
GSM1296063U_lesional_day43126.3945
GSM1296064E_lesional_day43145.3748
GSM1296067H_lesional_day43156.7946
GSM1296062M_lesional_day4397.5941
GSM1296068Q_lesional_day43318.7559
GSM1296050C_lesional_day43224.1754
GSM1296057D_lesional_day43174.250
GSM1296052I_lesional_day43137.848
GSM1296054J_lesional_day43100.5841
GSM1296049K_lesional_day43101.9142
GSM1296055W_lesional_day43128.6544
GSM1296053X_lesional_day4377.7438
GSM1296058Z_lesional_day4339.1629
GSM1296051F_lesional_day43157.650
GSM1296056O_lesional_day4393.6442
GSM1296065S_lesional_day43174.950
GSM1296061T_lesional_day4354.8431
GSM1296095A_non-lesional_pre-dose206.9653
GSM1296120B_non-lesional_pre-dose312.5459
GSM1296077C_non-lesional_pre-dose83.7940
GSM1296093D_non-lesional_pre-dose70.7135
GSM1296104E_non-lesional_pre-dose214.8753
GSM1296079F_non-lesional_pre-dose87.0940
GSM1296108G_non-lesional_pre-dose270.6957
GSM1296110H_non-lesional_pre-dose251.4354
GSM1296081I_non-lesional_pre-dose33.9127
GSM1296091J_non-lesional_pre-dose235.1856
GSM1296075K_non-lesional_pre-dose225.9756
GSM1296112L_non-lesional_pre-dose239.5653
GSM1296100M_non-lesional_pre-dose69.3935
GSM1296087O_non-lesional_pre-dose61.0936
GSM1296118P_non-lesional_pre-dose285.557
GSM1296114Q_non-lesional_pre-dose369.0562
GSM1296097R_non-lesional_pre-dose129.9845
GSM1296106S_non-lesional_pre-dose170.6849
GSM1296102U_non-lesional_pre-dose71.335
GSM1296122V_non-lesional_pre-dose186.0950
GSM1296089W_non-lesional_pre-dose128.2344
GSM1296083X_non-lesional_pre-dose111.3343
GSM1296116Y_non-lesional_pre-dose271.9156
GSM1296085Z_non-lesional_pre-dose84.1939