ProfileGDS5420 / 204164_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 53% 32% 35% 49% 45% 25% 36% 44% 52% 44% 44% 37% 47% 42% 39% 44% 45% 50% 47% 48% 40% 51% 44% 34% 46% 45% 46% 40% 39% 40% 55% 38% 53% 47% 37% 37% 41% 44% 56% 36% 43% 49% 47% 52% 52% 54% 48% 52% 52% 55% 50% 51% 51% 48% 36% 51% 44% 47% 47% 39% 48% 50% 35% 43% 54% 53% 57% 49% 56% 53% 58% 41% 52% 44% 51% 45% 44% 46% 58% 50% 43% 41% 38% 52% 48% 41% 43% 53% 45% 40% 41% 44% 47% 52% 44% 51% 53% 40% 54% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose205.253
GSM1296119B_lesional_pre-dose59.8232
GSM1296076C_lesional_pre-dose62.5435
GSM1296092D_lesional_pre-dose142.3549
GSM1296103E_lesional_pre-dose126.1545
GSM1296078F_lesional_pre-dose33.8825
GSM1296107G_lesional_pre-dose81.3936
GSM1296109H_lesional_pre-dose133.5144
GSM1296080I_lesional_pre-dose185.7352
GSM1296090J_lesional_pre-dose111.5344
GSM1296074K_lesional_pre-dose97.4544
GSM1296111L_lesional_pre-dose86.4137
GSM1296099M_lesional_pre-dose145.0347
GSM1296086O_lesional_pre-dose96.2342
GSM1296117P_lesional_pre-dose97.739
GSM1296113Q_lesional_pre-dose140.9844
GSM1296096R_lesional_pre-dose120.2945
GSM1296105S_lesional_pre-dose179.0350
GSM1296098T_lesional_pre-dose152.1647
GSM1296101U_lesional_pre-dose158.0748
GSM1296121V_lesional_pre-dose99.9640
GSM1296088W_lesional_pre-dose180.2451
GSM1296082X_lesional_pre-dose105.0544
GSM1296115Y_lesional_pre-dose69.7734
GSM1296084Z_lesional_pre-dose137.0246
GSM1296072B_lesional_day8135.2145
GSM1296069L_lesional_day8152.9246
GSM1296071P_lesional_day8108.9840
GSM1296070Y_lesional_day8105.5939
GSM1296073V_lesional_day896.7540
GSM1296034A_lesional_day15249.1855
GSM1296041G_lesional_day1590.7538
GSM1296035R_lesional_day15199.5853
GSM1296038U_lesional_day15141.8547
GSM1296047B_lesional_day1585.2537
GSM1296039E_lesional_day1571.7337
GSM1296042H_lesional_day15113.4641
GSM1296043L_lesional_day15135.2944
GSM1296037M_lesional_day1526456
GSM1296046P_lesional_day1586.6636
GSM1296044Q_lesional_day15129.9143
GSM1296045Y_lesional_day15184.249
GSM1296025C_lesional_day15140.2347
GSM1296033D_lesional_day15189.352
GSM1296027I_lesional_day15179.0752
GSM1296032J_lesional_day15226.2854
GSM1296024K_lesional_day15144.3148
GSM1296031W_lesional_day15201.852
GSM1296028X_lesional_day15187.852
GSM1296029Z_lesional_day15240.155
GSM1296026F_lesional_day1516050
GSM1296030O_lesional_day15167.7251
GSM1296040S_lesional_day15182.9551
GSM1296036T_lesional_day15166.1748
GSM1296048V_lesional_day1579.3436
GSM1296059A_lesional_day43181.0151
GSM1296066G_lesional_day43136.7844
GSM1296060R_lesional_day43138.7647
GSM1296063U_lesional_day43148.4547
GSM1296064E_lesional_day4381.6639
GSM1296067H_lesional_day43172.6748
GSM1296062M_lesional_day43179.8550
GSM1296068Q_lesional_day4385.1535
GSM1296050C_lesional_day43109.243
GSM1296057D_lesional_day43224.9554
GSM1296052I_lesional_day43197.5753
GSM1296054J_lesional_day43274.2957
GSM1296049K_lesional_day43154.449
GSM1296055W_lesional_day43258.5256
GSM1296053X_lesional_day43211.6653
GSM1296058Z_lesional_day43276.5258
GSM1296051F_lesional_day4395.6241
GSM1296056O_lesional_day43178.852
GSM1296065S_lesional_day4312444
GSM1296061T_lesional_day43185.0451
GSM1296095A_non-lesional_pre-dose119.8345
GSM1296120B_non-lesional_pre-dose136.0444
GSM1296077C_non-lesional_pre-dose126.2146
GSM1296093D_non-lesional_pre-dose288.8658
GSM1296104E_non-lesional_pre-dose172.150
GSM1296079F_non-lesional_pre-dose104.9243
GSM1296108G_non-lesional_pre-dose105.1541
GSM1296110H_non-lesional_pre-dose100.0238
GSM1296081I_non-lesional_pre-dose183.5852
GSM1296091J_non-lesional_pre-dose147.8848
GSM1296075K_non-lesional_pre-dose93.9241
GSM1296112L_non-lesional_pre-dose138.7243
GSM1296100M_non-lesional_pre-dose218.1953
GSM1296087O_non-lesional_pre-dose108.6345
GSM1296118P_non-lesional_pre-dose108.140
GSM1296114Q_non-lesional_pre-dose112.8141
GSM1296097R_non-lesional_pre-dose116.4344
GSM1296106S_non-lesional_pre-dose150.4647
GSM1296102U_non-lesional_pre-dose206.4252
GSM1296122V_non-lesional_pre-dose132.444
GSM1296089W_non-lesional_pre-dose200.4451
GSM1296083X_non-lesional_pre-dose205.7653
GSM1296116Y_non-lesional_pre-dose116.7340
GSM1296085Z_non-lesional_pre-dose224.8254